Prof. BERNABO' Nicola
Prof. BERNABO' Nicola

Email: nbernabo@unite.it

Telefono: 0861-266836

Facoltà di appartenenza: BIOSCIENZE E TECNOLOGIE AGRO-ALIMENTARI E AMBIENTALI


 
 
 
 

Curriculum accademico

 

Prof. Nicola Bernabò

 


FORMAZIONE

2004: Dottorato di Ricerca in "Endocrinologia degli Animali Domestici", Università di Bologna

2002: Master Universitario di primo livello in "Biotecnologie della Riproduzione", Università di Teramo

1999: Laurea in Meidicina Veterinaria, 110 e lode, Università of Pisa



ESPERIENZA PROFESSIONALE

 

2016- presente: Professore Associato (SSD-VET/02), Fisiologia Veterinaria, Facoltà di Bioscienze e Tecnologie Agro-Alimentari ed Ambientali, Università di Teramo.   

2008-2016:: Ricercatore Universitario (SSD-VET/02), Fisiologia Veterinaria, Facoltà di Medicina Veterinaria, Università di Teramo.

2008: Contrattista di Ricerca presso il Dipartimento di Scienze Biomediche Comparate, Università di Teramo, nell'ambito del progetto "VESTI L'AMBIENTE" per l'embryo-transfer nella specie ovina.

2007-2008: Ospite presso il Dipartimento di Medicina Sperimentale, Università di Milano-Bicocca, Milano, Laboratorio di Biochimica (Prof. P. Palestini) per l'estrazione e la caratterizzazione di microdomini lipidi nel seme di suino a differenti stati funzionali.

2007-2008 Professore a contratto di "Fisiologia dei gameti, maturazione e trasporto" CLS in Biotecnologie della Riproduzione, Università di Teramo.

2006-2007 Professore a contratto di "Spermatogenesi dei mammiferi" (Andrologia I), CLS in Biotecnologie della Riproduzione, Università di Teramo.

2004-2008: Assegnista di Ricerca, Sezione di Fisiologia Veterinaria, Dipartimento di Scienze Biomediche Comparate, Università di Teramo.

2004-2005: Svilppo, in collaborazione con la Prof.ssa P. Lucidi di un database relativo al comportamento equino (Cavalgiocare®).

2003 Collaborazione con Semenitaly s.p.a. (Modena, Italy) per lo sviluppo dell'extender CREA©.

2002: Svilppo, in collaborazione con la Prof.ssa P. Lucidi, di un test per la valutazione comportamntale del cane (Ethotest 2002©).

PREMI

1999: Premio "Benvenuto in SIVAR" per la tesi di laurea "Valutazione dell'attività acrosinica del seme di animali di interesse veterinario".

2008: Premio SISVet (Società Italiana delle Scienze Veterinarie) per la miglior comunicazione nel settore "Fisiologia Veterinaria"

ATTIVTA' DI RICERCA

L'attività di ricerca del Dr. Bernabò è focalizzata sulla Biologia della Riproduzione dei Mammiferi. In particolare su:

- l'effetto dell'esposizione a campi elettormagnetici a frequenza estremamente bassa (ELF-EMF) su funzione e morfologia degli spermatozoi;

- ruolo del sistema endocannabinoide durante capacitazione e reazione acrosomiale;

- identificazione dei meccanismi di trasduzione del segnale e rimodellamento del citoscheletro degli spermatozoi durante la capacitazione;

- sviluppo di modelli computazionali per rappresentare la capacitazione e la reazione acrosomiale;

- sviluppo di strategie volte a migliorare la qualità del seme suino refrigerato e congelato;

- studio della correlazione tra sviluppo follicolare e fenomeni angiogenetici nei mammiferi domestici.

Tutta l'attività scientifica è stata condotta sul modello ovivo e suino utilizzando le seguenti metodiche: immunoistochimica, immunicitochimica, microscopia confocale, spettrofluorimetria, citofluorimetria, RIA, ELISA, tecniche di modellizzazione computazionale.

MEMBRO DELLE SEGUENTI SOCIETA' SCIENTIFICHE

  • Società Italiana delle Scienze Veterinarie
  • Society for the Study of Reproduction (SSR)
  • European Society for Domestic Animal Reproduction (ESDAR) 


COLLABORAZIONI SCIENTIFICHE

  • Dipartimento di Scienze della Salute, Università di l'Aquila (Prof. Cecconi)

 

  • Departimento di Medicina Interna, Università di l'Aquila (Prof Francavilla)

 

  • Departimento di Medicina Sperimentale, Università di Milano-Bicocca (Prof. Palestini)

 




Curriculum english version

 

Prof. Nicola Bernabò, Associate Professor, Veterinary Physiology, Faculty of Bioscience and Agro-Food and Environmental Technology

 

EDUCATION AND PROFESSIONAL ACTIVITY

 

 

Dr. Bernabò organized and was invited to give several seminars for students and graduates in Veterinary Medicine, Biotechnology and Biotechnology of Reproduction on the following topics: biomedical statistics, systems biology, effects of electromagnetic fields on human and animal health, reproduction, animal physiology.

 

Dr. Bernabò was a supervisor (relatore) or a co-supervisor (corelatore) of several degree thesis, in Veterinary Medicine, Biotechnology and Biotechnology of Reproduction, concerning the physiology of reproduction, the effect of electromagnetic fields on cells and gametes, and the computational modeling of the spermatozoa signal transduction pathways. He also was as a co-tutor for two students of the Doctorate Course in "Molecular and Cellular Biotechnology."

 

2009-Present: is a member of the Academic Board of the Doctorate Course in "Cellular and Molecular Biotechnology", University of Teramo.

 

2009: course "Networks in Biology: Analysis, Modeling and Reverse Engineering" held in Bologna on 22 to 25 September 2009, organized by European Genetics Foundation, European Society of Human Genetics and European Molecular Biology Organization (EMBO). Director Dr. Diego di Bernardo (TIGEM).

 

2008: course "Peer Review in Theory and in Practice. Training course for scientific officers of European research funding organizations" held in Bologna on 8 to10 November 2008, organized by European Genetic Foundation and Telethon. Directors: Prof. Giovanni Romeo (University of Bologna) and Dr. Lucia Monaco (Telethon).

 

2008-present: University Researcher in Veterinary Physiology (SSD/VET02).

 

2008: contract for Research Activity with the Department of Biomedical Comparative Sciences, University of Teramo, for the "Vesti l'Ambiente" project.

 

2004-2008: Postoctoral fellowship, Veterinary Physiology Section, Department of Biomedical Comparative Sciences, University of Teramo. Project title "Development of innovative strategies for the cryopreservation of boar semen". 

 

2002: Collaboration with Semenitaly s.p.a. (Modena Italy), for the realization of boar semen extender CREA®.

 

2002: I° level Univeristy Master in "Biotechnology of Reproduction", University of Teramo (vote: 70/70). Title of the thesis: "Strategies for improving the quality of the refrigerated boar semen"

 

2001-2004: PhD in Endocrinology of Domestics Animal, University of Bologna. Title of the thesis: "The role of the cytoskeleton in the acquisition of fertilizing power of the boar sperm".

 

2000: Three years Diploma in  "Veterinary Acupuncture", Scuola di Agopuntira Tradizionale della Città di Firenze (vote: 30/30)

 

1999: Degree in Veterinay Medicine (vote: 110 cum laude), University of Pisa. Title of the thesis: "Determination of acrosin activity in semen of animals of veterinary interest".

 

 

SCIENTIFIC SOCIETIES MEMBRESHIP 

  • Società Italiana delle Scienze Veterinarie (SISVet)
  • Society for the Study of Reproduction (SSR)
  • European Society for Domestic Animal Reproduction (ESDAR) 

 

RESEARCH INTEREST

   

Main research interests   

 

 1.      Computational modellization of signal transduction pathways involved in sperm capacitation and acrosome reaction.

Mammalian spermatozoa, immediately after the ejaculation are unable to fertilize the oocyte. To reach their fertilizing ability the male gametes must complete a process of functional maturation, the capacitation, within the female genital tract. Only once the capacitation is completed the spermatozoa can respond to the oocyte interaction with the exocytosis of acrosome content, acrosome reaction (AR). These post-ejaculatory events are under the attention of Researchers from more than fifty years but their basic knowledge is still unsatisfactory. This failure could be due not to the insufficiency of available data, but to the inability to manage them in a descriptive model. Thus, we decided to adopt a computational modeling-based strategy to represent these events, taking into account their complexity. In particular we adopted a biological networks-based approach and we developed and in vitro validated a computational model representing the signal transduction pathways involved in sperm capacitation and acrosome reaction. At present we are studying the possibility to perform a dynamical modelization, by using the Random Boolean Networks (RBN). In this context we  have undertaken a collaboration dr. Marco Verdecchia (see Scientific Collaborations). Overall we have produced the following papers on international Journals (Bernabò N, Mattioli M, Barboni B. The spermatozoa caught in the net: the biological networks to study the male gametes post-ejaculatory life. BMC Systems Biology 2010, 4:87; N. Bernabò, P. Berardinelli, A. Mauro, V. Russo, P. Lucidi, M. Mattioli, B. Barboni. "The role of actin in capacitation-related signaling: an in silico and in vitro study." BMC Syst Biol. 2011 Mar 30;5(1):47; N. Bernabò, I. Saponaro, M. Mattioli and B. Barboni.   "Signaling Strategy in Spermatozoa Activation of Sea Urchin, C. elegans and Human: Three Different Players for the Same Melody." J Bioengineer & Biomedical Sci 2012, S3 INVITED PAPER) and a book chapter (N. Bernabò, M. Mattioli and B. Barboni: "A Systems Biology Approach to Understanding Male Infertility". In: Male Infertility,  Edited by Anu Bashamboo and Kenneth David McElreavey, Published by  InTech, April 20, 2012 ISBN 978-953-51-0562-6), as well as presentations at national meetings.

 

2.      Effect of electromagnetic fields on reproduction.

Modern society implies the continuous exposure of general population to electromagnetic radiation, whose effects on human health, in particular reproduction, are still unknown. In this context we evaluated the effect of the exposure to extremely low frequency electromagnetic fields (ELF-EMF) on male gametes and on female genital tract, defining a threshold limit and a dose-dependent relationship between field exposure and cell damage. Overall we have produced the following papers on international Journals (N. Bernabò, E. Tettamanti, M. G. Pistilli, D. Nardinocchi, P. Berardinelli, M. Mattioli, B. Barboni  "Effects of 50 Hz extremely low frequency electromagnetic field on the morphology and function of boar spermatozoa capacitated in vitro" Theriogenology. 2007 Mar 1;67(4):801; N. Bernabò, E. Tettamanti, V. Russo, A. Martelli, M. Turriani, M. Mattoli, B. Barboni. "Extremely low frequency electromagnetic field exposure affects fertilization outcome in swine animal model." Theriogenology 73(9):1293-305 2010), as well as presentations at national meetings  

 

  3.      Involvement of endocannabioid system in modulation of sperm capacitation and acrosome reaction. Several indications converge in suggesting that endocannabinoid system (ECS) acs as a key factor in modulating male gametes function. We have characterized ECS in boar spermatozoa and we have investigated the signaling systems involved in its metabolism. Overall we have produced the following papers on international Journals (M. Maccarrone, B Barboni, A Paradisi, N Bernabò, V Gasperi, M G Pistilli, F Fezza, P Lucidi , M Mattioli: "Characterization of the Endocannabinoid System in Boar Spermatozoa and Implications for Sperm Capacitation and Acrosome Reaction".  J Cell Sci. 2005 Oct 1;118(Pt 19):4393-404; N. Bernabò, M. G. Pistilli, M. Mattioli, B. Barboni. "Role of TRPV1 channels in boar spermatozoa acquisition of fertilizing ability." 323(2): 224-31 Mol Cell Endocr (2010); L. Botto, N. Bernabò, P. Palestini P,  B. Barboni   "Bicarbonate induces the membranes reorganization and the CB1R and TRPV1 endocannabionid receptors migration in lipid microdomains in capacitating boar spermatozoa." J Membr Biol. 2010 Dec;238(1-3):33-41; Barboni B, Bernabo` N, Palestini P, Botto L, Pistilli MG, et al. (2011) "Type-1 Cannabinoid Receptors Reduce Membrane Fluidity of Capacitated Boar Sperm by Impairing Their Activation by Bicarbonate." PLoS ONE 6(8): e23038. doi:10.1371/journal.pone.0023038; N. Bernabò, P. Palestini, M. Chiarini, M. Maccarrone, M. Mattioli, B. Barboni: "Endocannabinoid-binding CB1 and TRPV1 receptors as modulators of sperm capacitation". Communicative Integrative Biology, Volume 5, Issue 1 (January/February) 2012. INVITED PAPER) as well as presentations at national meetings.

 

Other research interests

 

4.      Female reproduction. At preset the major interest of Dr. Bernabò in female reproduction is the study of dynamics of ovarian angiogenesis. In particular he contributed to the adoption of advanced statistical techniques (i.e. cluster analysis) and to the study of ovarian hemodynamic. Some recent papers on this topic are: Martelli A, Berardinelli P, Russo V, Bernabò N, Gioia L, Mattioli M, Barboni B, "Spatio-temporal analysis of VEGF expression and blood vessels remodelling after LH surge in pig ovarian follicles" J Mol Endocrinol. Feb;36(1):107-19 2006; Martelli A, Bernabò N, Berardinelli P, Russo V, Rinaldi C, Di Giacinto O, Mauro A, Barboni B. Vascular supply as a discriminating factor for pig preantral follicle selection. Reproduction 137 45-58 2009; Martelli A., Palmerini M.G., Russo V., Rinaldi C., Bernabò N., Di Giacinto O., Berardinelli P., Nottola S.A., Macchiarelli G., Barboni B. "Blood vessel remodelling in pig ovarian follicles during the periovulatory period: an immunohistochemistry and SEM-corrosion casting study" Reproductive Biology and Endocrinology 7, 72 2009).   

 

 5.      Amniotic stem cells in regenerative medicine. Dr. Bernabò contributed to the research activity carried on the use of stem cells in regenerative medicine  by the Physiology group. In particular he undertaken a collaboration with the Laboratory of Macromolecules, Department of  Chemistry and Industrial Chemistry, University of Pisa, coordinated by Prof. Francesco Ciardelli, with the aim to study the biomechanical proprieties of control and transplanted ovine tendon, as documented by the following international publications (Colosimo A, Curini V, Russo V, Mauro A, Bernabò N, Marchisio M, Alfonsi M,Muttini A, Mattioli M, Barboni B. "Characterization, GFP gene nucleofection and allotransplantation in injured tendons of ovine amniotic fluid-derived stem cells". Cell Transplant. 2012 Apr 10. PubMed PMID: 22507078; Barboni B, Russo V, Curini V, Mauro A, Martelli A, Muttini A, Bernabò N, Valbonetti L, Marchisio M, Digiacinto O, Berardinelli P, Mattioli M. "Achilles tendon regeneration can be improved by amniotic cells allotrasnplantation". Cell Transplant. 2012 Apr 10. PubMed PMID: 22507232).  

 

 EXTERNAL SCIENTIFIC COLLABORATIONS   

 

2011-present: collaboration with dr. Verdecchia, Responsible for the hydrological modeling of CETEMPS (Centro di Eccellenza di Telerilevamento e Modellistica numerica per la Previsione di eventi Severi), Department of Physics, University of L'Aquila, for the development of a software able to modelize the calcium clearance during human and boar sperm capacitation (SpeBiNet) based on biological networks theory and for computational simulation of dynamic complex events that characterize the biology of male gametes by Random Boolean Networks (RBN).   2011-present: collaboration with prof. Lubas, Head of the Laboratory of Clinical Biochemistry and Haematology,  Faculty of Veterinary Medicine, University of Pisa, for the application of advanced statistical models to the study of microcytosis in dog.  

2007- present: Dr. Bernabò has spent several periods of time (over 8 months in total) at the Laboratory of Biochemistry, Department of Experimental Medicine, University of Milano-Bicocca, coordinated by Prof. Paola Palestini, for the isolation and biochemical characterization of membrane microdomains from sperm membrane and for the measurement of the chemical-physical characteristics of the membranes of spermatozoa in different functional state.

 

EDITORIAL ACTIVITY

 

Dr. Bernabò was invited reviewer for important Journals in the field of reproduction (International Journal of Andrology, Reproduction, Molecular Reproduction and Development).

 

2012-present: Member of Editorial Board of "ISRN Physiology" peer-reviewed, open access journal that publishes original research articles, review articles, and clinical studies in all areas of physiology.

 

2011-present:  Physiology Faculty Member for "WebMedCentral, an open access biomedical publisher" with editorial responsibilities.

 

AWARDS

 

2012: the idea of ​​"The virtual spermatozoon: computational model able to simulate the behavior of spermatozoa." has been reported in the fourth edition of the international competition of ideas "K-idea: intuizioni, idee, invenzioni," organized by "Kilometro Rosso. Parco scientifico tecnologico ", Bergamo, Italy, in collaboration with Brembo, Jacobacci & Partners, MultiPhysiX LAB, Whirpool and Umania.

 

2008: SISVet (Società Italiana delle Scienze Veterinarie) Award for the best communication in "Veterinary physiology", LXII meeting of SISVeT, S. Benedetto del Tronto, 23-25 sett. 2008.

 

2000: Award "Benvenuto in SIVAR" SIVAR (Società Italiana Veterinari per Animali da Reddito) for the degree thesis.

Pubblicazioni

 

 

List of papers of Nicola BERNABO’ published in international peer-reviewed Journals (Scopus

EXPORT DATE:23 Jan 2017):

 

  1. BERNABO’, N., Greco, L., Mattioli, M., Barboni, B. A scientometric analysis of reproductive medicine (2016) Scientometrics, 109 (1), pp. 103-120.

 

  1. BERNABO’, N., Agostino, R.D., Ordinelli, A., Mattioli, M., Barboni, B. The maturation of murine spermatozoa membranes within the epididymis, a computational biology perspective (2016) Systems Biology in Reproductive Medicine, 62 (5), pp. 299-308.

 

  1. BERNABO’, N., Ciccarelli, R., Mattioli, M., Barboni, B. Effect of non-ionizing electromagnetic fields of anthropic origin on male fertility (2016) Current Chemical Biology, 10 (1), pp. 18-31.

 

  1. BERNABO’, N., Ordinelli, A., Ramal Sanchez, M., Mattioli, M., Barboni, B. Networks Models of Actin Dynamics during Spermatozoa Postejaculatory Life: A Comparison among Human-Made and Text Mining-Based Models  (2016) BioMed Research International, 2016, art. no. 9795409.

 

  1. BERNABO’, N., Mattioli, M., Barboni, B. Signal transduction in the activation of spermatozoa compared to other signalling pathways: A biological networks study

(2015) International Journal of Data Mining and Bioinformatics, 12 (1), pp. 59-69.

 

  1. BERNABO’, N., Greco, L., Ordinelli, A., Mattioli, M., Barboni, B. Capacitation-Related Lipid Remodeling of Mammalian Spermatozoa Membrane Determines the Final Fate of Male Gametes: A Computational Biology Study (2015) OMICS A Journal of Integrative Biology, 19 (11), pp. 712-721.

 

  1. BERNABO’, N., Barboni, B., Maccarrone, M. The biological networks in studying cell signal transduction complexity: The examples of sperm capacitation and of endocannabinoid system (2014) Computational and Structural Biotechnology Journal, 11 (18), pp. 11-21.

 

  1. Mauro, A., Martelli, A., Berardinelli, P., Russo, V., BERNABO’, N., Di Giacinto, O., Mattioli, M., Barboni, B. Effect of antiprogesterone RU486 on VEGF expression and blood vessel remodeling on ovarian follicles before ovulation (2014) PLoS ONE, 9 (4), art. no. e95910.

 

  1. BERNABO’, N., Saponaro, I., Tettamanti, E., Mattioli, M., Barboni, B. Acute exposure to a 2mT static magnetic field affects ionic homeostasis of in vitro grown porcine granulosa cells (2014) Bioelectromagnetics, 35 (3), pp. 231-234.

 

  1. Gavazza, A., Ricci, M., Brettoni, M., Gugliucci, B., Pasquini, A., Rispoli, D., BERNABO’, N., Lubas, G. Retrospective and prospective investigations about "quatrefoil" erythrocytes in canine blood smears 2014) Veterinary Medicine International, 2014.

 

  1. BERNABO’, N., Ordinelli, A., Di Agostino, R., Mattioli, M., Barboni, B. Network analyses of sperm-egg recognition and binding: Ready to rethink fertility mechanisms? (2014) OMICS A Journal of Integrative Biology, 18 (12), pp. 740-753.

 

  1. BERNABO’, N., Palestini, P., Botto, L., Mattioli, M., Barboni, B. Membrane dynamics occurring during capacitation of mammalian spermatozoa (2014) Spermatozoa: Biology, Motility and Function and Chromosomal Abnormalities, pp. 99-122.

 

  1. BERNABO’, N., Mattioli, M., Barboni, B. Computational modeling in male reproduction (2013) Advances in Computational Modeling Research: Theory, Developments and Applications, pp. 33-58.

 

  1. BERNABO’, N., Mattioli, M., Barboni, B. Signal transduction pathways: When network topology can explain cell function (2013) Network Topologies: Types, Performance Impact and Advantages/Disadvantages, pp. 79-101.

 

  1. BERNABO’, N., Barboni, B., Maccarrone, M. Systems biology analysis of the endocannabinoid system reveals a scale-free network with distinct roles for anandamide and 2-arachidonoylglycerol (2013) OMICS A Journal of Integrative Biology, 17 (12), pp. 646-654.

 

  1. Gioia, L., Saponaro, I., BERNABO’, N., Tettamanti, E., Mattioli, M., Barboni, B.Chronic exposure to a 2 mT static magnetic field affects the morphology, the metabolism and the function of in vitro cultured swine granulosa cells 2013) Electromagnetic Biology and Medicine, 32 (4), pp. 536-550.

 

  1. Tosi, U., BERNABO’, N., Verni, F., Valbonetti, L., Muttini, A., Mattioli, M., Barboni, B. Postpartum reproductive activities and gestation length in Martina Franca jennies, an endangered Italian donkey breed (2013) Theriogenology, 80 (2), pp. 120-124.

 

  1. Marruchella, G., BERNABO’, N., Valbonetti, L. Quantitative assessment of bronchiolar smooth muscle in healthy and diseased porcine lungs 2013) Research in Veterinary Science, 94 (3), pp. 641-643.

 

  1. Russo, V., BERNABO’, N., Di Giacinto, O., Martelli, A., Mauro, A., Berardinelli, P., Curini, V., Nardinocchi, D., Mattioli, M., Barboni, B. H3K9 Trimethylation Precedes DNA Methylation during Sheep Oogenesis: HDAC1, SUV39H1, G9a, HP1, and Dnmts Are Involved in These Epigenetic Events (2013) Journal of Histochemistry and Cytochemistry, 61 (1), pp. 75-89.

 

  1. Colosimo, A., Curini, V., Russo, V., Mauro, A., BERNABO’, N., Marchisio, M., Alfonsi, M., Muttini, A., Mattioli, M., Barboni, B. Characterization, GFP gene nucleofection, and allotransplantation in injured tendons of ovine amniotic fluid-derived stem cells (2013) Cell Transplantation, 22 (1), pp. 99-117.

 

  1. Lucidi, P., Bacco, G., Sticco, M., Mazzoleni, G., Benvenuti, M., BERNABO’, N., Trentini, R. Assessment of motor laterality in foals and young horses (Equus caballus) through an analysis of derailment at trot (2013) Physiology and Behavior, 109 (1), pp. 8-13.

 

  1. Saponaro, I., BERNABO’, N., Mattioli, M. Signaling in sperm activation: A common strategy for different organisms (2013) Trends in Veterinary Sciences: Current Aspects in Veterinary Morphophysiology, Biochemistry, Animal Production, Food Hygiene and Clinical Sciences, pp. 41-44.

 

  1. Colosimo, A., Russo, V., Mauro, A., Curini, V., Marchisio, M., BERNABO’, N., Alfonsi, M., Mattioli, M., Barboni, B. Prolonged in vitro expansion partially affects phenotypic features and osteogenic potential of ovine amniotic fluid-derived mesenchymal stromal cells (2013) Cytotherapy, 15 (8), pp. 930-950.

 

  1. Barboni, B., Russo, V., Curini, V., Mauro, A., Martelli, A., Muttini, A., BERNABO’, N., Valbonetti, L., Marchisio, M., Giacinto, O.D., Berardinelli, P., Mattioli, M. Achilles tendon regeneration can be improved by amniotic epithelial cell allotransplantation (2012) Cell Transplantation, 21 (11), pp. 2377-2395.

 

  1. Oddi, S., BERNABO’, N., Di Tommaso, M., Angelucci, C.B., Bisicchia, E., Mattioli, M., Maccarrone, M. DNA uptake in swine sperm: Effect of plasmid topology and methyl-beta-cyclodextrin-mediated cholesterol depletion (2012) Molecular Reproduction and Development, 79 (12), pp. 853-860.

 

  1. Saponaro, I., BERNABO’, N., Todisco, G., Lucidi, P., Berardinelli, P. Role of actin in spermatozoa function through biological network theory (2012) Veterinary Science: Current Aspects in Biology, Animal Pathology, Clinic and Food Hygiene, 9783642232718, pp. 33-37.

 

  1. Gavazza, A., Rispoli, D., BERNABO’, N., Lubas, G. Retrospective and observational investigation of canine microcytosis in relationship to sex, breed, diseases, and other complete blood count parameters (2012) Comparative Clinical Pathology, 21 (5), pp. 545-553.

 

  1. BERNABO’, N., Palestini, P., Chiarini, M., Maccarrone, M., Mattioli, M., Barboni, B. Endocannabinoid-binding CB1 and TRPV1 receptors as modulators of sperm capacitation (2012) Communicative and Integrative Biology, 5 (1), pp. 68-70.

 

  1. Barboni, B., BERNABO’, N., Palestini, P., Botto, L., Pistilli, M.G., Charini, M., Tettamanti, E., Battista, N., Maccarrone, M., Mattioli, M. Type-1 Cannabinoid receptors reduce membrane fluidity of capacitated boar sperm by impairing their activation by bicarbonate (2011) PLoS ONE, 6 (8), art. no. e23038.

 

  1. BERNABO’, N., Berardinelli, P., Mauro, A., Russo, V., Lucidi, P., Mattioli, M., Barboni, B. The role of actin in capacitation-related signaling: An in silico and in vitro study (2011) BMC Systems Biology, 5, art. no. 47.

 

  1. Botto, L., BERNABO’, N., Palestini, P., Barboni, B. Bicarbonate induces membrane reorganization and CBR1 and TRPV1 endocannabinoid receptor migration in lipid microdomains in capacitating boar spermatozoa (2010) Journal of Membrane Biology, 238 (1-3), pp. 33-41.

 

  1. BERNABO’, N., Pistilli, M.G., Mattioli, M., Barboni, B. Role of TRPV1 channels in boar spermatozoa acquisition of fertilizing ability (2010) Molecular and Cellular Endocrinology, 323 (2), pp. 224-231.

 

  1. BERNABO’, N., Mattioli, M., Barboni, B. The spermatozoa caught in the net: The biological networks to study the male gametes post-ejaculatory life

(2010) BMC Systems Biology, 4, art. no. 87 .

 

  1. BERNABO’, N., Tettamanti, E., Russo, V., Martelli, A., Turriani, M., Mattoli, M., Barboni, B. Extremely low frequency electromagnetic field exposure affects fertilization outcome in swine animal model (2010) Theriogenology, 73 (9), pp. 1293-1305.

 

  1. BERNABO’, N., Pistilli, M.G., Falasca, G., Curini, V., Garofalo, M.L.A., Turriani, M., Mattioli, M., Barboni, B. Role of TRPV1 channels during the acquisition of fertilizing ability in boar spermatozoa (2010) Veterinary Research Communications, 34 (SUPPL.1).

 

  1. Martelli, A., Palmerini, M.G., Russo, V., Rinaldi, C., BERNABO’, N., Di Giacinto, O., Berardinelli, P., Nottola, S.A., Macchiarelli, G., Barboni, B. Blood vessel remodeling in pig ovarian follicles during the periovulatory period: an immunohistochemistry and SEM-corrosion casting study. (2009) Reproductive biology and endocrinology : RB&E, 7, p. 72.

 

  1. BERNABO’, N., Palestini, P., Botto, L., Pistilli, M.G., Falasca, G., Gloria, A., Mattioli, M., Barboni, B. Lipidic microdomain reorganization during the in vitro capacitation of boar spermatozoa (2009) Veterinary Research Communications, 33 (SUPPL. 1).

 

  1. Martelli, A., BERNABO’, N., Berardinelli, P., Russo, V., Rinaldi, C., Di Giacinto, O., Mauro, A., Barboni, B. Vascular supply as a discriminating factor for pig preantral follicle selection (2009) Reproduction, 137 (1), pp. 45-58.

 

  1. BERNABO’, N., Pistilli, M.G., Gloria, A., Pancrazio, C., Falasca, G., Barboni, B., Mattioli, M. Factors affecting TRPV1 receptor immunolocalization in boar spermatozoa capacitated in vitro (2008) Veterinary Research Communications, 32 (SUPPL. 1),

 

  1. Martelli, A., Russo, V., Mauro, A., Nardinocchi, D., Rinaldi, C., BERNABO’, N., Berardinelli, P., Mattioli, M. Role of VEGF in pig preantral follicles (2008) Veterinary Research Communications, 32 (SUPPL. 1).

 

  1. Cecconi, S., Mauro, A., Capacchietti, G., Berardinelli, P., BERNABO’, N., Di Vincenzo, A.R., Mattioli, M., Barboni, B. Meiotic maturation of incompetent prepubertal sheep oocytes is induced by paracrine factor(s) released by gonadotropin-stimulated oocyte-cumulus cell complexes and involves mitogen-activated protein kinase activation (2008) Endocrinology, 149 (1), pp. 100-107.

 

  1. Pistilli, M.G., BERNABO’, N., Gloria, A., Mattioli, M., Barboni, B. Effect of CB1 receptors on boar sperm plasma membrane (2007) Veterinary Research Communications, 31 (SUPPL. 1), pp. 189-191.

 

  1. Russo, V., Martelli, A., Berardinelli, P., Di Giacinto, O., BERNABO’, N., Fantasia, D., Mattioli, M., Barboni, B. Modifications in chromatin morphology and organization during sheep oogenesis (2007) Microscopy Research and Technique, 70 (8), pp. 733-744.

 

  1. BERNABO’, N., Tettamanti, E., Pistilli, M.G., Nardinocchi, D., Berardinelli, P., Mattioli, M., Barboni, B. Effects of 50 Hz extremely low frequency magnetic field on the morphology and function of boar spermatozoa capacitated in vitro (2007) Theriogenology, 67 (4), pp. 801-815.

 

  1. Pistilli, M.G., BERNABO’, N., Lucidi, P., Di Giacinto, O., Di Pancrazio, C., Paradisi, A., Maccarrone, M., Barboni, B. Role of the endogenous cannabinoid system on function of boar spermatozoa (2006) Veterinary Research Communications, 30 (SUPPL. 1), pp. 195-198.

 

  1. Barboni, B., Martelli, A., Berardinelli, P., Russo, V., Turriani, M., BERNABO’, N., Lucidi, P., Mattioli, M. Ovarian follicle vascularization in fasted pig (2006) Theriogenology, 66 (2), p. 496.

 

  1. Martelli, A., Berardinelli, P., Russo, V., Mauro, A., BERNABO’, N., Gioia, L., Mattioli, M., Barboni, B. Spatio-temporal analysis of vascular endothelial growth factor expression and blood vessel remodelling in pig ovarian follicles during the periovulatory period (2006) Journal of Molecular Endocrinology, 36 (1), pp. 107-119.

 

  1. Lucidi, P., BERNABO’, N., Panunzi, M., Villa, P.D., Mattioli, M. Ethotest: A new model to identify (shelter) dogs' skills as service animals or adoptable pets (2005) Applied Animal Behaviour Science, 95 (1-2), pp. 103-122.

 

  1. Maccarrone, M., Barboni, B., Paradisi, A., BERNABO’, N., Gasperi, V., Pistilli, M.G., Fezza, F., Lucidi, P., Mattioli, M. Characterization of the endocannabinoid system in boar spermatozoa and implications for sperm capacitation and acrosome reaction (2005) Journal of Cell Science, 118 (19), pp. 4393-4404.

 

  1. Barboni, B., Lucidi, P., BERNABO’, N., Pistilli, M.G. Signalling compartmentalization involved in the boar sperm acrosome reaction (2004) Veterinary Research Communications, 28 (SUPPL. 1), pp. 157-160.

 

  1. Ptak, G., Tischner, M., BERNABO’, N., Loi, P. Donor-dependent developmental competence of oocytes from lambs subjected to repeated hormonal stimulation

(2003) Biology of Reproduction, 69 (1), pp. 278-285.

 

  1. Barboni, B., Mattioli, M., Gioia, L., Turriani, M., Capacchietti, G., Berardinelli, P., BERNABO’, N. Preovulatory rise of NGF in ovine follicular fluid: Possible involvement in the control of oocyte maturation (2002) Microscopy Research and Technique, 59 (6), pp. 516-521.

 

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