Prof. MACCARRONE Mauro
Prof. MACCARRONE Mauro

Email: mmaccarrone@unite.it

Telefono: 0861-266875

Facoltà di appartenenza: BIOSCIENZE E TECNOLOGIE AGRO-ALIMENTARI E AMBIENTALI


 
 
 
 

Curriculum accademico

 
E' risultato vincitore delle seguenti borse di studio:
NATO competitive fellowship (1986); ELGRA (European Low Gravity Research Association) fellowship (1988); borsa di studio del Centro Ettore Majorana, Erice (1989); EMBL fellowship (1992); FEBS short term fellowship (1995). Nel 1986 vince il Concorso nazionale "Un Esperimento nello Spazio" (organizzato da Agenzia Spaziale Italiana, Alenia e Centro Ricerche FIAT).

E' membro del comitato editoriale delle riviste Lipids in Health and Disease, Anti-Allergy and Anti-Inflammatory Agents in Medicinal Chemistry, Current Neurovascular Research, The Open Neuroscience Journal, Current Medicinal Chemistry, Cardiovascular Psychiatry and Neurology, Cannabinoids.

E' referee di numerose riviste internazionali (tra cui JAMA, PNAS, Journal of Biological Chemistry, FASEB Journal, Biological Psychiatry, Cell Death and Differentiation, Journal of Molecular Biology, Endocrinology, Thrombosis and Haemostasis, Journal of Neurochemistry, Biochemical Journal, Molecular Human Reproduction, British Journal of Pharmacology, European Journal of Biochemistry), oltre che delle associazioni The Israel Science Foundation, The Science Foundation Ireland, TheGerman Research Foundation (DFG), The Austrian Science Fund (FWF) e The Wellcome Trust.

E' membro delle seguenti Associazioni scientifiche: 1) European Low Gravity Research Association (ELGRA, dal 1989); 2) Società Italiana di Biochimica (SIB, dal 1991); 3) Reale Società Olandese di Chimica (KNCV, dal 1992 al 1995); 4) New York Academy of Sciences (NYAS, dal 1994 al 1995); 5) International Cannabinoid Research Society (ICRS, dal 1999); 6) American Society for Biochemistry and Molecular Biology (dal 2003); 7) Federation of American Societies for Experimental Biology (dal 2003); 8) American Association for the Advancement of Science (dal 2004); 9) American Chemical Society (dal 2007); 10) Society for Neuroscience (nel 2009).

Nel 2000 ha pubblicato il libro "Biochimica del rene e delle vie urinarie" (pp. 470), per i tipi della Edizioni Mediche Scientifiche Internazionali (EMSI, Roma), nel 2006 ha contribuito al libro Biochimica degli Alimenti e della Nutrizione (pp. 285, Piccin Editore, Padova) e nel 2009 ha pubblicato il libro Gli Endocannabinoidi: Nuovi Mediatori Lipidici di Rilevanza Biomedica (pp. 222, Piccin Editore, Padova). È titolare del brevetto europeo "Early diagnosis of miscarriage in human beings" (n. EP1272659B1, del 5 Luglio 2006), del brevetto internazionale "Design and synthesis of biotinylated probes for N-acyl-ethanolamines" (n. PCT/EP2006/061988, del 2 Maggio 2006) e del brevetto italiano "Metodo per la diagnosi in vitro della malattia di Huntington" (n. RM2007A000259, dell'8 Maggio 2007), per i quali è stato iscritto come inventore presso l'European Patent Office. È titolare di due brevetti internazionali su farmaci diretti verso il sistema endocannabinoide, i cui dettagli sono ancora riservati.

Nel 2003 è stato insignito del premio internazionale per la ricerca scientifica "4th Royan International Research Award for Reproductive Biomedicine" dal Royan Institute di Teheran (Iran), sotto l'egida dell'ESHRE (European Society for Human Reproduction and Embryology).


Nel 2007 è stato insignito del premio internazionale per la ricerca scientifica "2007 IACM Award for Basic Research" dalla International Association for Cannabis as Medicine.


Nel 2008 è stato Founding member of the "European Cannabinoid Research Alliance (ECRA)", una rete di eccellenza dei ricercatori europei sugli (endo)cannabinoidi.


Nel 2008 ha ricevuto il "BIO#4 Mission Team Achievement Award" dalla European Space Agency, per l'esperimento ROALD ospitato a bordo della International Space Station.

Nel 2009 è stato eletto President-Elect (2010) e poi President (2011) della "International Cannabinoid Research Society (ICRS)".


Interessi scientifici
I risultati ottenuti sono stati pubblicati su riviste internazionali in più di 240 lavori in extenso (I.F. totale > 1000, citazioni > 4430, h-index = 39), incluse più di 30review e più di 40invited papers, oltre a più di 150 comunicazioni a Congresso.

Curriculum english version

 
Awarded the following fellowships:
NATO competitive fellowship (1986); ELGRA (European Low Gravity Research Association) fellowship (1988); Ettore Majorana Center (Erice) fellowship (1989); EMBL fellowship (1992); FEBS short term fellowship (1995). In 1986 won the national contest "An Experiment in Space" (organized by Italian Space Agency (ASI), Alenia and FIAT Research Center).

Member of the editorial board of the journals Lipids in Health and Disease; Anti-Allergy and Anti-Inflammatory Agents in Medicinal Chemistry; Current Neurovascular Research; The Open Neuroscience Journal; Current Medicinal Chemistry; Cardiovascular Psychiatry and Neurology; Cannabinoids.


Referee for several journals of science (including JAMA, PNAS, Journal of Biological Chemistry, FASEB Journal, Biological Psychiatry, Cell Death and Differentiation, Journal of Molecular Biology, Endocrinology, Thrombosis and Haemostasis, Journal of Neurochemistry, Biochemical Journal, Molecular Human Reproduction, British Journal of Pharmacology, European Journal of Biochemistry), for The Israel Science Foundation, The Science Foundation Ireland, the German Research Foundation (DFG), the Austrian Science Fund (FWF) and The Wellcome Trust.

Holder of the European patent "Early diagnosis of miscarriage in human beings" (n. EP1272659B1, 5 July 2006), of the international patent "Design and synthesis of biotinylated probes for N-acyl-ethanolamines" (n. PCT/EP2006/061988, 2 May 2006), and of the Italian patent "Metodo per la diagnosi in vitro della malattia di Huntington" (n. RM2007A000259, 8 May 2007). Holder of two more international patents on endocannabinoid-oriented drugs, that cannot yet be disclosed.

Awarded the "4th Royan International Research Award for Reproductive Biomedicine" (2003) by the Royan Institute of Tehran (Iran), under the patronage of the ESHRE (European Society for Human Reproduction and Embryology). Awarded the "2007 IACM Award for Basic Research" by the International Association for Cannabis as Medicine. Awarded the "BIO#4 Mission Team Achievement Award" by the European Space Agency, for the ROALD experiment flown on the International Space Station (2008).

Founding member of the "European Cannabinoid Research Alliance (ECRA)", a leading network of (endo)cannabinoid researchers in Europe (2008).

President-Elect (2010) and then President (2011) of the "International Cannabinoid Research Society (ICRS)".


Scientific interests
Published more than 240 full papers (total I.F. > 1000, citations > 4430, h-index = 39), including more than 30review articles and more than 40 invited papers in international refereed journals, besides more than 150 Congress communications.

Pubblicazioni

 

Lavori idell'ultimo quinquennio presenti su SCOPUS

Oddi, S., Stepniewski, T.M., Totaro, A., Selent, J., Scipioni, L., Dufrusine, B., Fezza, F., Dainese, E., Maccarrone, M.

Palmitoylation of cysteine 415 of CB1 receptor affects ligand-stimulated internalization and selective interaction with membrane cholesterol and caveolin 1

(2017) Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1862 (5), pp. 523-532.

 

Tiribuzi, R., Crispoltoni, L., Chiurchiù, V., Casella, A., Montecchiani, C., Del Pino, A.M., Maccarrone, M., Palmerini, C.A., Caltagirone, C., Kawarai, T., Orlacchio, A., Orlacchio, A.

Trans-crocetin improves amyloid-β degradation in monocytes from Alzheimer's Disease patients

(2017) Journal of the Neurological Sciences, 372, pp. 408-412.

 

Zoratto, F., Romano, E., Pascale, E., Pucci, M., Falconi, A., Dell'Osso, B., Maccarrone, M., Laviola, G., D'Addario, C., Adriani, W.

Down-regulation of serotonin and dopamine transporter genes in individual rats expressing a gambling-prone profile: A possible role for epigenetic mechanisms

(2017) Neuroscience, 340, pp. 101-116.

 

 Soethoudt, M., Grether, U., Fingerle, J., Grim, T.W., Fezza, F., De Petrocellis, L., Ullmer, C., Rothenhäusler, B., Perret, C., Van Gils, N., Finlay, D., Macdonald, C., Chicca, A., Gens, M.D., Stuart, J., De Vries, H., Mastrangelo, N., Xia, L., Alachouzos, G., Baggelaar, M.P., Martella, A., Mock, E.D., Deng, H., Heitman, L.H., Connor, M., Di Marzo, V., Gertsch, J., Lichtman, A.H., Maccarrone, M., Pacher, P., Glass, M., Van Der Stelt, M.

Cannabinoid CB 2 receptor ligand profiling reveals biased signalling and off-target activity

(2017) Nature Communications, 8, art. no. 13958, .

 

Barbonetti, A., Bisogno, T., Battista, N., Piscitelli, F., Micillo, A., Francavilla, S., Maccarrone, M., Francavilla, F.

2-arachidonoylglycerol levels are increased in leukocytospermia and correlate with seminal macrophages

(2017) Andrology, 5 (1), pp. 87-94.

 

Zamberletti, E., Piscitelli, F., De Castro, V., Murru, E., Gabaglio, M., Colucci, P., Fanali, C., Prini, P., Bisogno, T., Maccarrone, M., Campolongo, P., Banni, S., Rubino, T., Parolaro, D.

Lifelong imbalanced LA/ALA intake impairs emotional and cognitive behavior via changes in brain endocannabinoid system

(2017) Journal of Lipid Research, 58 (2), pp. 301-316.

 

Chiurchiù, V., Rapino, C., Talamonti, E., Leuti, A., Lanuti, M., Gueniche, A., Jourdain, R., Breton, L., Maccarrone, M.

Anandamide suppresses proinflammatory T cell responses in vitro through type-1 cannabinoid receptor-mediated mTOR Inhibition in human keratinocytes

(2016) Journal of Immunology, 197 (9), pp. 3545-3553.

 

Maccarone, R., Rapino, C., Zerti, D., Di Tommaso, M., Battista, N., Di Marco, S., Bisti, S., Maccarrone, M.

Modulation of Type-1 and Type-2 cannabinoid receptors by saffron in a rat model of retinal neurodegeneration

(2016) PLoS ONE, 11 (11), art. no. e0166827, .

 

Pucci, M., Micioni Di Bonaventura, M.V., Giusepponi, M.E., Romano, A., Filaferro, M., Maccarrone, M., Ciccocioppo, R., Cifani, C., D'Addario, C.

Epigenetic regulation of nociceptin/orphanin FQ and corticotropin-releasing factor system genes in frustration stress-induced binge-like palatable food consumption

(2016) Addiction Biology, 21 (6), pp. 1168-1185.

 

Chiurchiù, V., Leuti, A., Cencioni, M.T., Albanese, M., De Bardi, M., Bisogno, T., Centonze, D., Battistini, L., Maccarrone, M.

Modulation of monocytes by bioactive lipid anandamide in multiple sclerosis involves distinct Toll-like receptors

(2016) Pharmacological Research, 113, pp. 313-319.

 

D'Addario, C., Micale, V., Di Bartolomeo, M., Stark, T., Pucci, M., Sulcova, A., Palazzo, M., Babinska, Z., Cremaschi, L., Drago, F., Carlo Altamura, A., Maccarrone, M., Dell'Osso, B.

A preliminary study of endocannabinoid system regulation in psychosis: Distinct alterations of CNR1 promoter DNA methylation in patients with schizophrenia

(2016) Schizophrenia Research, . Article in Press.

 

Gentile, A., Fresegna, D., Musella, A., Sepman, H., Bullitta, S., De Vito, F., Fantozzi, R., Usiello, A., Maccarrone, M., Mercuri, N.B., Lutz, B., Mandolesi, G., Centonze, D.

Interaction between interleukin-1β and type-1 cannabinoid receptor is involved in anxiety-like behavior in experimental autoimmune encephalomyelitis

(2016) Journal of Neuroinflammation, 13 (1), art. no. 231, . 

 

Bisogno, T., Oddi, S., Piccoli, A., Fazio, D., Maccarrone, M.

Type-2 cannabinoid receptors in neurodegeneration

(2016) Pharmacological Research, 111, pp. 721-730. .

 

 Chiurchiù, V., Leuti, A., Dalli, J., Jacobsson, A., Battistini, L., MaCcarrone, M., Serhan, C.N.

Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses

(2016) Science Translational Medicine, 8 (353), art. no. 353ra111, . 

 

Chiurchiù, V., Maccarrone, M.

Bioactive lipids as modulators of immunity, inflammation and emotions

(2016) Current Opinion in Pharmacology, 29, pp. 54-62.

 

Fuso, A., Iyer, A.M., van Scheppingen, J., Maccarrone, M., Scholl, T., Hainfellner, J.A., Feucht, M., Jansen, F.E., Spliet, W.G., Krsek, P., Zamecnik, J., Mühlebner, A., Aronica, E.

Promoter-Specific Hypomethylation Correlates with IL-1β Overexpression in Tuberous Sclerosis Complex (TSC)

(2016) Journal of Molecular Neuroscience, 59 (4), pp. 464-470. Cited 1 time.

 

Bilgin, M., Born, P., Fezza, F., Heimes, M., Mastrangelo, N., Wagner, N., Schultz, C., Maccarrone, M., Eaton, S., Nadler, A., Wilm, M., Shevchenko, A.

Lipid Discovery by Combinatorial Screening and Untargeted LC-MS/MS

(2016) Scientific Reports, 6, art. no. 27920,

 

 Catanzaro, G., Pucci, M., Viscomi, M.T., Lanuti, M., Feole, M., Angeletti, S., Grasselli, G., Mandolesi, G., Bari, M., Centonze, D., D'Addario, C., Maccarrone, M.

Epigenetic modifications of Dexras 1 along the nNOS pathway in an animal model of multiple sclerosis

(2016) Journal of Neuroimmunology, 294, pp. 32-40.

 

Verrotti, A., Castagnino, M., Maccarrone, M., Fezza, F.

Plant-Derived and Endogenous Cannabinoids in Epilepsy

(2016) Clinical Drug Investigation, 36 (5), pp. 331-340..

 

Ferri, E., Arosio, B., D'Addario, C., Galimberti, D., Gussago, C., Pucci, M., Casati, M., Fenoglio, C., Abbate, C., Rossi, P.D., Scarpini, E., MacCarrone, M., Mari, D.

Gene promoter methylation and expression of Pin1 differ between patients with frontotemporal dementia and Alzheimer's disease

(2016) Journal of the Neurological Sciences, 362, pp. 283-286..

 

Madeo, G., Schirinzi, T., Maltese, M., Martella, G., Rapino, C., Fezza, F., Mastrangelo, N., Bonsi, P., MacCarrone, M., Pisani, A.

Dopamine-dependent CB1receptor dysfunction at corticostriatal synapses in homozygous PINK1 knockout mice

(2016) Neuropharmacology, 101, pp. 460-470

 

Mukhopadhyay, P., Baggelaar, M., Erdelyi, K., Cao, Z., Cinar, R., Fezza, F., Ignatowska-Janlowska, B., Wilkerson, J., Van Gils, N., Hansen, T., Ruben, M., Soethoudt, M., Heitman, L., Kunos, G., Maccarrone, M., Lichtman, A., Pacher, P., Van Der Stelt, M.

The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity

(2016) British Journal of Pharmacology, 173 (3), pp. 446-458.

 

Businaro, R., Corsi, M., Azzara, G., Di Raimo, T., Laviola, G., Romano, E., Ricci, L., Maccarrone, M., Aronica, E., Fuso, A., Ricci, S.

Interleukin-18 modulation in autism spectrum disorders

(2016) Journal of Neuroinflammation, 13 (1), art. no. 2, .

 

Maccarrone, M.

Need for methods to investigate endocannabinoid signaling

(2016) Methods in Molecular Biology, 1412, pp. 1-8.

 

 

Bari, M., Feole, M., Maccarrone, M.

Assay of FAAH activity

(2016) Methods in Molecular Biology, 1412, pp. 131-136.

 

Fezza, F., Mastrangelo, N., Maccarrone, M.

Assay of NAPE-PLD activity

(2016) Methods in Molecular Biology, 1412, pp. 123-130.

 

Chiurchiù, V., Orlacchio, A., Maccarrone, M.

Is modulation of oxidative stress an answer? the state of the art of redox therapeutic actions in neurodegenerative diseases

(2016) Oxidative Medicine and Cellular Longevity, 2016, art. no. 7909380, .

 

Oddi, S., Totaro, A., Maccarrone, M.

Visualization of endocannabinoids in the cell

(2016) Methods in Molecular Biology, 1412, pp. 277-282.

 

Gabrielli, M., Battista, N., Riganti, L., Prada, I., Antonucci, F., Cantone, L., Lombardi, M., Matteoli, M., Maccarrone, M., Verderio, C.

Active endocannabinoids are secreted on the surface of microglial microvesicles

(2015) SpringerPlus, 4, art. no. L29, pp. 1-32.

 

Chakrabarti, B., Persico, A., Battista, N., Maccarrone, M.

Endocannabinoid Signaling in Autism

(2015) Neurotherapeutics, 12 (4), pp. 837-847.

 

Battista, N., Bari, M., Maccarrone, M.

Endocannabinoids and reproductive events in health and disease

(2015) Handbook of Experimental Pharmacology, 231, pp. 341-365.

 

Battista, N., Bari, M., Maccarrone, M.

Endocannabinoids and reproductive events in health and disease

(2015) Endocannabinoids, pp. 341-365.

 

Marco, E.M., Rapino, C., Caprioli, A., Borsini, F., Laviola, G., Maccarrone, M., Lodola, A.

Potential therapeutic value of a novel FAAH inhibitor for the treatment of anxiety

(2015) PLoS ONE, 10 (9), art. no. e0137034, .

 

Gasperi, V., Evangelista, D., Oddi, S., Florenzano, F., Chiurchiù, V., Avigliano, L., Catani, M.V., Maccarrone, M.

Regulation of inflammation and proliferation of human bladder carcinoma cells by type-1 and type-2 cannabinoid receptors

(2015) Life Sciences, 138, pp. 41-51

 

Ribeiro, A., Pontis, S., Mengatto, L., Armirotti, A., Chiurchiù, V., Capurro, V., Fiasella, A., Nuzzi, A., Romeo, E., Moreno-Sanz, G., Maccarrone, M., Reggiani, A., Tarzia, G., Mor, M., Bertozzi, F., Bandiera, T., Piomelli, D.

A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation

(2015) ACS Chemical Biology, 10 (8), pp. 1838-1846.

 

Lanuti, M., Talamonti, E., Maccarrone, M., Chiurchiu, V.

Erratum: Activation of GPR55 receptors exacerbates oxLDL-induced lipid accumulation and inflammatory responses, while reducing cholesterol efflux from human macrophages (PLoS ONE 10 5 (e0126839) (DOI:10.1371/journal.pone.0126839))

(2015) PLoS ONE, 10 (6), art. no. e0131850, .

 

 

Lanuti, M., Talamonti, E., Maccarrone, M., Chiurchiú, V.

Activation of GPR55 receptors exacerbates oxLDL-induced lipid accumulation and inflammatory responses, while reducing cholesterol efflux from human macrophages

(2015) PLoS ONE, 10 (5), art. no. e0126839, .

 

Gasperi, V., Evangelista, D., Savini, I., Del Principe, D., Avigliano, L., Maccarrone, M., Catani, M.V.

Downstream effects of endocannabinoid on blood cells: Implications for health and disease

(2015) Cellular and Molecular Life Sciences, 72 (17), pp. 3235-3252.

 

Mancino, S., Burokas, A., Gutiérrez-Cuesta, J., Gutiérrez-Martos, M., Martín-García, E., Pucci, M., Falconi, A., D'Addario, C., Maccarrone, M., Maldonado, R.

Epigenetic and proteomic expression changes promoted by eating addictive-like behavior

(2015) Neuropsychopharmacology, 40 (12), pp. 2788-2800.

 

Maccarrone, M., Bab, I., Bíró, T., Cabral, G.A., Dey, S.K., Di Marzo, V., Konje, J.C., Kunos, G., Mechoulam, R., Pacher, P., Sharkey, K.A., Zimmer, A.

Endocannabinoid signaling at the periphery: 50 years after THC

(2015) Trends in Pharmacological Sciences, 36 (5), art. no. 1213, pp. 277-296.

 

Chiurchiu, V., Battistini, L., Maccarrone, M.

Endocannabinoid signalling in innate and adaptive immunity

(2015) Immunology, 144 (3), pp. 352-364.

 

Gabrielli, M., Battista, N., Riganti, L., Prada, I., Antonucci, F., Cantone, L., Matteoli, M., Maccarrone, M., Verderio, C.

Active endocannabinoids are secreted on extracellular membrane vesicles

(2015) EMBO Reports, 16 (2), pp. 213-220.

 

Chiurchiù, V., Leuti, A., Maccarrone, M.

Cannabinoid Signaling and Neuroinflammatory Diseases: A Melting pot for the Regulation of Brain Immune Responses

(2015) Journal of Neuroimmune Pharmacology, 10 (2), pp. 268-280.

 

Maccarrone, M.

Endocannabinoid signaling in female reproductive events: A potential therapeutic target?

(2015) Expert Opinion on Therapeutic Targets, 19 (11), pp. 1423-1427.

 

Chiurchiù, V., Lanuti, M., De Bardi, M., Battistini, L., Maccarrone, M.

The differential characterization of GPR55 receptor in human peripheral blood reveals a distinctive expression in monocytes and NK cells and a proinflammatory role in these innate cells

(2015) International Immunology, 27 (3), pp. 153-160.

 

Cifani, C., Micioni Di Bonaventura, M.V., Pucci, M., Giusepponi, M.E., Romano, A., Di Francesco, A., Maccarrone, M., D'Addario, C.

Regulation of hypothalamic neuropeptides gene expression in diet induced obesity resistant rats: Possible targets for obesity prediction?

(2015) Frontiers in Neuroscience, 9 (MAY), art. no. 187, .

 

Di Francesco, A., Arosio, B., Falconi, A., Micioni Di Bonaventura, M.V., Karimi, M., Mari, D., Casati, M., Maccarrone, M., D'Addario, C.

Global changes in DNA methylation in Alzheimer's disease peripheral blood mononuclear cells

(2015) Brain, Behavior, and Immunity, 45, pp. 139-144.

 

Pacioni, G., Rapino, C., Zarivi, O., Falconi, A., Leonardi, M., Battista, N., Colafarina, S., Sergi, M., Bonfigli, A., Miranda, M., Barsacchi, D., Maccarrone, M.

Truffles contain endocannabinoid metabolic enzymes and anandamide

(2015) Phytochemistry, 110, pp. 104-110.

 

di Francesco, A., Falconi, A., di Germanio, C., Micioni Di Bonaventura, M.V., Costa, A., Caramuta, S., Del Carlo, M., Compagnone, D., Dainese, E., Cifani, C., Maccarrone, M., D'Addario, C.

Extravirgin olive oil up-regulates CB1; tumor suppressor gene in human colon cancer cells and in rat colon via epigenetic mechanisms

(2015) Journal of Nutritional Biochemistry, 26 (3), pp. 250-258.

 

Gasperi, V., Avigliano, L., Evangelista, D., Oddi, S., Chiurchiù, V., Lanuti, M., Maccarrone, M., Catani, M.V.

2-Arachidonoylglycerol enhances platelet formation from human megakaryoblasts

(2014) Cell Cycle, 13 (24), pp. 3938-3947

 

Fezza, F., Bari, M., Florio, R., Talamonti, E., Feole, M., Maccarrone, M.

Endocannabinoids, related compounds and their metabolic routes

(2014) Molecules, 19 (11), pp. 17078-17106.

 

Fezza, F., Maccarrone, M.

Endocannabinoid biochemistry: What do we know after 50 years?

(2014) Cannabinoids, pp. 53-94.

 

Bernabò, N., Barboni, B., Maccarrone, M.

The biological networks in studying cell signal transduction complexity: The examples of sperm capacitation and of endocannabinoid system

(2014) Computational and Structural Biotechnology Journal, 11 (18), pp. 11-21.

 

Musella, A., Sepman, H., Mandolesi, G., Gentile, A., Fresegna, D., Haji, N., Conrad, A., Lutz, B., Maccarrone, M., Centonze, D.

Pre- and postsynaptic type-1 cannabinoid receptors control the alterations of glutamate transmission in experimental autoimmune encephalomyelitis

(2014) Neuropharmacology, 79, pp. 567-572.

 

Chiurchiù, V., Maccarrone, M., Orlacchio, A.

The role of reticulons in neurodegenerative diseases

(2014) NeuroMolecular Medicine, 16 (1), pp. 3-15.

 

Chiurchiù, V., Lanuti, M., Catanzaro, G., Fezza, F., Rapino, C., Maccarrone, M.

Detailed characterization of the endocannabinoid system in human macrophages and foam cells, and anti-inflammatory role of type-2 cannabinoid receptor

(2014) Atherosclerosis, 233 (1), pp. 55-63

 

Dainese, E., De Fabritiis, G., Sabatucci, A., Oddi, S., Angelucci, C.B., Di Pancrazio, C., Giorgino, T., Stanley, N., Del Carlo, M., Cravatt, B.F., Maccarrone, M.

Membrane lipids are key modulators of the endocannabinoid-hydrolase FAAH

(2014) Biochemical Journal, 457 (3), pp. 463-472.

 

Maccarrone, M.

Activation of platelets by endocannabinoids: Distinct agonists or arachidonate reservoirs?

(2014) Platelets, 25 (6), pp. 463-464.

 

Bisogno, T., Maccarrone, M.

Endocannabinoid signaling and its regulation by nutrients

(2014) BioFactors, 40 (4), pp. 373-380.

 

Rapino, C., Battista, N., Bari, M., Maccarrone, M.

Endocannabinoids as biomarkers of human reproduction

(2014) Human Reproduction Update, 20 (4), art. no. dmu004, pp. 501-516.

 

Cecconi, S., Rossi, G., Castellucci, A., D'Andrea, G., Maccarrone, M.

Endocannabinoid signaling in mammalian ovary in the memory of Riccardo Del Gratta (1966-2013).

(2014) European Journal of Obstetrics Gynecology and Reproductive Biology, 178, pp. 6-11.

 

Maccarrone, M., Guzmán, M., MacKie, K., Doherty, P., Harkany, T.

Programming of neural cells by (endo)cannabinoids: From physiological rules to emerging therapies

(2014) Nature Reviews Neuroscience, 15 (12), pp. 786-801.

 

Barbonetti, A., Vassallo, M.R.C., Costanzo, M., Battista, N., Maccarrone, M., Francavilla, S., Francavilla, F.

Involvement of cannabinoid receptor-1 activation in mitochondrial depolarizing effect of lipopolysaccharide in human spermatozoa

(2014) Andrology, 2 (4), pp. 502-509.

 

Fonseca, B.M., Battista, N., Correia-da-Silva, G., Rapino, C., Maccarrone, M., Teixeira, N.A.

Activity of anandamide (AEA) metabolic enzymes in rat placental bed

(2014) Reproductive Toxicology, 49, pp. 74-77.

 

Dainese, E., Sabatucci, A., Pintus, F., Medda, R., Angelucci, C.B., Floris, G., Maccarrone, M.

Domain mobility as probed by small-angle X-ray scattering may account for substrate access to the active site of two copper-dependent amine oxidases

(2014) Acta Crystallographica Section D: Biological Crystallography, 70 (8), pp. 2101-2110.

 

Battista, N., Sergi, M., Montesano, C., Napoletano, S., Compagnone, D., Maccarrone, M.

Analytical approaches for the determination of phytocannabinoids and endocannabinoids in human matrices

(2014) Drug Testing and Analysis, 6 (1-2), pp. 7-16.

 

Tantimonaco, M., Ceci, R., Sabatini, S., Catani, M.V., Rossi, A., Gasperi, V., Maccarrone, M.

Physical activity and the endocannabinoid system: An overview

(2014) Cellular and Molecular Life Sciences, 71 (14), pp. 2681-2698.

 

Arosio, B., D'Addario, C., Gussago, C., Casati, M., Tedone, E., Ferri, E., Nicolini, P., Rossi, P.D., Maccarrone, M., Mari, D.

Peripheral blood mononuclear cells as a laboratory to study dementia in the elderly

(2014) BioMed Research International, 2014, art. no. 169203, .

 

den Boon, F.S., Chameau, P., Houthuijs, K., Bolijn, S., Mastrangelo, N., Kruse, C.G., Maccarrone, M., Wadman, W.J., Werkman, T.R.

Endocannabinoids produced upon action potential firing evoke a Cl− current via type-2 cannabinoid receptors in the medial prefrontal cortex

(2014) Pflugers Archiv European Journal of Physiology, 466 (12), pp. 2257-2268.

 

Fezza, F., Marrone, M.C., Avvisati, R., Di Tommaso, M., Lanuti, M., Rapino, C., Mercuri, N.B., Maccarrone, M., Marinelli, S.

Distinct modulation of the endocannabinoid system upon kainic acid-induced in vivo seizures and in vitro epileptiform bursting

(2014) Molecular and Cellular Neuroscience, 62, pp. 1-9.

 

Nader, J., Rapino, C., Gennequin, B., Chavant, F., Francheteau, M., Makriyannis, A., Duranti, A., Maccarrone, M., Solinas, M., Thiriet, N.

Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors

(2014) Neuropharmacology, 87, pp. 214-221.

 

Gasperi, V., Rapino, C., Battista, N., Bari, M., Mastrangelo, N., Angeletti, S., Dainese, E., Maccarrone, M.

A Functional Interplay between 5-Lipoxygenase and μ -Calpain Affects Survival and Cytokine Profile of Human Jurkat T Lymphocyte Exposed to Simulated Microgravity

(2014) BioMed Research International, 2014, art. no. 782390, .

 

Gasperi, V., Evangelista, D., Chiurchiù, V., Florenzano, F., Savini, I., Oddi, S., Avigliano, L., Catani, M.V., Maccarrone, M.

2-Arachidonoylglycerol modulates human endothelial cell/leukocyte interactions by controlling selectin expression through CB1 and CB2 receptors

(2014) International Journal of Biochemistry and Cell Biology, 51 (1), pp. 79-88.

 

D'Addario, C., Micioni Di Bonaventura, M.V., Pucci, M., Romano, A., Gaetani, S., Ciccocioppo, R., Cifani, C., Maccarrone, M.

Endocannabinoid signaling and food addiction

(2014) Neuroscience and Biobehavioral Reviews, 47 (1), pp. 203-224.

 

Giacominelli-Stuffler, R., Frangipane di Regalbono, A., Traversa, D., Geurden, T., Marcer, F., Di Francesco, A., Angelini, C., di Cesare, A., Storelli, M.M., Maccarrone, M.

The expression and activity of 5-LOX in the large intestine of horses harbouring encysted cyathostomin larvae

(2014) Veterinary Parasitology, 203 (1-2), pp. 96-101.

 

 

Di Venere, A., Nicolai, E., Ivanov, I., Dainese, E., Adel, S., Angelucci, B.C., Kuhn, H., Maccarrone, M., Mei, G.

Probing conformational changes in lipoxygenases upon membrane binding: Fine-tuning by the active site inhibitor ETYA

(2014) Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1841 (1), pp. 1-10.

 

Gasperi, V., Ceci, R., Tantimonaco, M., Talamonti, E., Battista, N., Parisi, A., Florio, R., Sabatini, S., Rossi, A., Maccarrone, M.

The fatty acid amide hydrolase in lymphocytes from sedentary and active subjects

(2014) Medicine and Science in Sports and Exercise, 46 (1), pp. 24-32.

 

Latini, L., Bisicchia, E., Sasso, V., Chiurchiù, V., Cavallucci, V., Molinari, M., Maccarrone, M., Viscomi, M.T.

Cannabinoid CB2 receptor (CB2R) stimulation delays rubrospinal mitochondrial-dependent degeneration and improves functional recovery after spinal cord hemisection by ERK1/2 inactivation

(2014) Cell Death and Disease, 5 (9), art. no. e1404, .

 

Massimi, A., Malaponti, M., Federici, L., Vinciguerra, D., Manca Bitti, M.L., Vottero, A., Ghizzoni, L., Maccarrone, M., Cappa, M., Bernardini, S., Porzio, O.

Functional and structural analysis of four novel mutations of CYP21A2 gene in Italian patients with 21-hydroxylase deficiency

(2014) Hormone and Metabolic Research, 46 (7), pp. 515-520.

 

Dell'Osso, B., D'Addario, C., Carlotta Palazzo, M., Benatti, B., Camuri, G., Galimberti, D., Fenoglio, C., Scarpini, E., Di Francesco, A., MacCarrone, M., Carlo Altamura, A.

Epigenetic modulation of BDNF gene: Differences in DNA methylation between unipolar and bipolar patients

(2014) Journal of Affective Disorders, 166, pp. 330-333.

 

Rossi, S., Bozzali, M., Bari, M., Mori, F., Studer, V., Motta, C., Buttari, F., Cercignani, M., Gravina, P., Mastrangelo, N., Castelli, M., Mancino, R., Nucci, C., Sottile, F., Bernardini, S., Maccarrone, M., Centonze, D.

Association between a genetic variant of type-1 cannabinoid receptor and inflammatory neurodegeneration in multiple sclerosis

(2013) PLoS ONE, 8 (12), art. no. e82848, .

 

Maccarrone, M.

Endocannabinoids as markers of sperm quality: Hot spots

(2013) Frontiers in Endocrinology, 4 (NOV), art. no. Article 169, .

 

Bernabò, N., Barboni, B., Maccarrone, M.

Systems biology analysis of the endocannabinoid system reveals a scale-free network with distinct roles for anandamide and 2-arachidonoylglycerol

(2013) OMICS A Journal of Integrative Biology, 17 (12), pp. 646-654.

 

Galve-Roperh, I., Chiurchiù, V., Díaz-Alonso, J., Bari, M., Guzmán, M., Maccarrone, M.

Cannabinoid receptor signaling in progenitor/stem cell proliferation and differentiation

(2013) Progress in Lipid Research, 52 (4), pp. 633-650.

 

Pucci, M., Rapino, C., Di Francesco, A., Dainese, E., D'Addario, C., Maccarrone, M.

Epigenetic control of skin differentiation genes by phytocannabinoids

(2013) British Journal of Pharmacology, 170 (3), pp. 581-591.

 

Marco, E.M., Scattoni, M.L., Rapino, C., Ceci, C., Chaves, N., Macrì, S., Maccarrone, M., Laviola, G.

Emotional, endocrine and brain anandamide response to social challenge in infant male rats

(2013) Psychoneuroendocrinology, 38 (10), pp. 2152-2162.

 

Di Francesco, A., Arosio, B., Gussago, C., Dainese, E., Mari, D., D'Addario, C., MacCarrone, M.

Involvement of 5-lipoxygenase in Alzheimer's disease: A role for DNA methylation

(2013) Journal of Alzheimer's Disease, 37 (1), pp. 3-8.

 

Maccarrone, M.

Endocannabinoid signaling in cancer: A rather complex puzzle

(2013) Trends in Pharmacological Sciences, 34 (8), pp. 426-427

 

Maccarrone, M.

Endocannabinoid signaling in cancer: a rather complex puzzle

(2013) Trends in Pharmacological Sciences, . Article in Press.

 

Bari, M., Battista, N., Valenza, M., Mastrangelo, N., Malaponti, M., Catanzaro, G., Centonze, D., Finazzi-Agrò, A., Cattaneo, E., Maccarrone, M.

In vitro and in vivo models of Huntington's disease show alterations in the endocannabinoid system

(2013) FEBS Journal, 280 (14), pp. 3376-3388.

 

Bisicchia, E., Chiurchiù, V., Viscomi, M.T., Latini, L., Fezza, F., Battistini, L., Maccarrone, M., Molinari, M.

Activation of type-2 cannabinoid receptor inhibits neuroprotective and antiinflammatory actions of glucocorticoid receptor α: When one is better than two

(2013) Cellular and Molecular Life Sciences, 70 (12), pp. 2191-2204.

 

Galimberti, D., D'Addario, C., Dell'Osso, B., Fenoglio, C., Marcone, A., Cerami, C., Cappa, S.F., Palazzo, M.C., Arosio, B., Mari, D., MacCarrone, M., Bresolin, N., Altamura, A.C., Scarpini, E.

Progranulin gene (GRN) promoter methylation is increased in patients with sporadic frontotemporal lobar degeneration

(2013) Neurological Sciences, 34 (6), pp. 899-903.

 

Finazzi Agrò, A., MacCarrone, M.

Surfing the (endo)cannabinoids wave

(2013) FEBS Journal, 280 (9), p. 1873.

 

 

Bisogno, T., Maccarrone, M.

Latest advances in the discovery of fatty acid amide hydrolase inhibitors

(2013) Expert Opinion on Drug Discovery, 8 (5), pp. 509-522.

 

D'Addario, C., Di Francesco, A., Pucci, M., Finazzi Agrò, A., MacCarrone, M.

Epigenetic mechanisms and endocannabinoid signalling

(2013) FEBS Journal, 280 (9), pp. 1905-1917.

 

Chiurchiù, V., Cencioni, M.T., Bisicchia, E., De Bardi, M., Gasperini, C., Borsellino, G., Centonze, D., Battistini, L., Maccarrone, M.

Distinct modulation of human myeloid and plasmacytoid dendritic cells by anandamide in multiple sclerosis

(2013) Annals of Neurology, 73 (5), pp. 626-636.

 

Battista, N., Di Sabatino, A., Di Tommaso, M., Biancheri, P., Rapino, C., Giuffrida, P., Papadia, C., Montana, C., Pasini, A., Vanoli, A., Lanzarotto, F., Villanacci, V., Corazza, G.R., Maccarrone, M.

Altered Expression of Type-1 and Type-2 Cannabinoid Receptors in Celiac Disease

(2013) PLoS ONE, 8 (4), art. no. e62078, .

 

D'Addario, C., Di Francesco, A., Trabace, L., Finazzi Agrò, A., Cuomo, V., Maccarrone, M.

Endocannabinoid signaling in Alzheimer's disease: Current knowledge and future directions

(2013) Journal of Biological Regulators and Homeostatic Agents, 27 (2 SUPPL.), pp. 61-73

 

Gebeh, A.K., Willets, J.M., Bari, M., Hirst, R.A., Marczylo, T.H., Taylor, A.H., Maccarrone, M., Konje, J.C.

Elevated anandamide and related N-acylethanolamine levels occur in the peripheral blood of women with ectopic pregnancy and are mirrored by changes in peripheral fatty acid amide hydrolase activity

(2013) Journal of Clinical Endocrinology and Metabolism, 98 (3), pp. 1226-1234.

 

D'Addario, C., Caputi, F.F., Ekström, T.J., Di Benedetto, M., Maccarrone, M., Romualdi, P., Candeletti, S.

Ethanol induces epigenetic modulation of prodynorphin and pronociceptin gene expression in the rat amygdala complex

(2013) Journal of Molecular Neuroscience, 49 (2), pp. 312-319.

 

Compagnucci, C., Di Siena, S., Bustamante, M.B., Di Giacomo, D., Di Tommaso, M., Maccarrone, M., Grimaldi, P., Sette, C.

Type-1 (CB1) Cannabinoid Receptor Promotes Neuronal Differentiation and Maturation of Neural Stem Cells

(2013) PLoS ONE, 8 (1), art. no. e54271, .

 

D'Addario, C., Dell'Osso, B., Galimberti, D., Palazzo, M.C., Benatti, B., Di Francesco, A., Scarpini, E., Altamura, A.C., MacCarrone, M.

Epigenetic modulation of BDNF gene in patients with major depressive disorder

(2013) Biological Psychiatry, 73 (2), .

 

Butini, S., Gemma, S., Brindisi, M., Maramai, S., Minetti, P., Celona, D., Napolitano, R., Borsini, F., Cabri, W., Fezza, F., Merlini, L., Dallavalle, S., Campiani, G., MacCarrone, M.

Identification of a novel arylpiperazine scaffold for fatty acid amide hydrolase inhibition with improved drug disposition properties

(2013) Bioorganic and Medicinal Chemistry Letters, 23 (2), pp. 492-495.

 

Maccarrone, M.

Editorial: Regulation of GPCRs by the membrane environment

(2013) Current Medicinal Chemistry, 20 (1), pp. 2-3.

 

Gasperi, V., Dainese, E., Oddi, S., Sabatucci, A., Maccarrone, M.

GPR55 and its interaction with membrane lipids: Comparison with other endocannabinoid-binding receptors

(2013) Current Medicinal Chemistry, 20 (1), pp. 64-78.

 

Sergi, M., Battista, N., Montesano, C., Curini, R., MacCarrone, M., Compagnone, D.

Determination of the two major endocannabinoids in human plasma by μ-SPE followed by HPLC-MS/MS

(2013) Analytical and Bioanalytical Chemistry, 405 (2-3), pp. 785-793

 

Grimaldi, P., Pucci, M., Di Siena, S., Di Giacomo, D., Pirazzi, V., Geremia, R., MacCarrone, M.

The faah gene is the first direct target of estrogen in the testis: Role of histone demethylase LSD1

(2012) Cellular and Molecular Life Sciences, 69 (24), pp. 4177-4190.

 

Bambang, K.N., Lambert, D.G., Lam, P.M.W., Quenby, S., Maccarrone, M., Konje, J.C.

Immunity and early pregnancy events: Are endocannabinoids the missing link?

(2012) Journal of Reproductive Immunology, 96 (1-2), pp. 8-18.

 

Oddi, S., Bernabò, N., Di Tommaso, M., Angelucci, C.B., Bisicchia, E., Mattioli, M., Maccarrone, M.

DNA uptake in swine sperm: Effect of plasmid topology and methyl-beta-cyclodextrin-mediated cholesterol depletion

(2012) Molecular Reproduction and Development, 79 (12), pp. 853-860.

 

Di Venere, A., Dainese, E., Fezza, F., Angelucci, B.C., Rosato, N., Cravatt, B.F., Finazzi-Agrò, A., Mei, G., MacCarrone, M.

Rat and human fatty acid amide hydrolases: Overt similarities and hidden differences

(2012) Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1821 (11), pp. 1425-1433.

 

Lewis, S.E.M., Rapino, C., Di Tommaso, M., Pucci, M., Battista, N., Paro, R., Simon, L., Lutton, D., Maccarrone, M.

Differences in the Endocannabinoid System of Sperm from Fertile and Infertile Men

(2012) PLoS ONE, 7 (10), art. no. e47704, .

 

Rossi, S., Sacchetti, L., Napolitano, F., De Chiara, V., Motta, C., Studer, V., Musella, A., Barbieri, F., Bari, M., Bernardi, G., Maccarrone, M., Usiello, A., Centonze, D.

Interleukin-1β causes anxiety by Interacting with the endocannabinoid system

(2012) Journal of Neuroscience, 32 (40), pp. 13896-13905.

 

Giacominelli-Stuffler, R., Marruchella, G., Storelli, M.M., Sabatucci, A., Angelucci, C.B., Maccarrone, M.

5-Lipoxygenase and cyclooxygenase-2 in the lungs of pigs naturally affected by enzootic pneumonia and porcine pleuropneumonia

(2012) Research in Veterinary Science, 93 (2), pp. 898-903.

 

Lewis, S.E.M., Paro, R., Borriello, L., Simon, L., Robinson, L., Dincer, Z., Riedel, G., Battista, N., Maccarrone, M.

Long-term use of HU210 adversely affects spermatogenesis in rats by modulating the endocannabinoid system

(2012) International Journal of Andrology, 35 (5), pp. 731-740.

 

Perrotta, A., Arce-Leal, N., Tassorelli, C., Gasperi, V., Sances, G., Blandini, F., Serrao, M., Bolla, M., Pierelli, F., Nappi, G., MacCarrone, M., Sandrini, G.

Acute reduction of anandamide-hydrolase (FAAH) activity is coupled with a reduction of nociceptive pathways facilitation in medication-overuse headache subjects after withdrawal treatment

(2012) Headache, 52 (9), pp. 1350-1361.

 

Battista, N., Di Sabatino, A., Di Tommaso, M., Biancheri, P., Rapino, C., Vidali, F., Papadia, C., Montana, C., Pasini, A., Lanzini, A., Villanacci, V., Corazza, G.R., Maccarrone, M.

Abnormal anandamide metabolism in celiac disease

(2012) Journal of Nutritional Biochemistry, 23 (10), pp. 1245-1248.

 

Butini, S., Brindisi, M., Gemma, S., Minetti, P., Cabri, W., Gallo, G., Vincenti, S., Talamonti, E., Borsini, F., Caprioli, A., Stasi, M.A., Di Serio, S., Ros, S., Borrelli, G., Maramai, S., Fezza, F., Campiani, G., MacCarrone, M.

Discovery of potent inhibitors of human and mouse fatty acid amide hydrolases

(2012) Journal of Medicinal Chemistry, 55 (15), pp. 6898-6915.

 

Caprioli, A., Coccurello, R., Rapino, C., Di Serio, S., Di Tommaso, M., Vertechy, M., Vacca, V., Battista, N., Pavone, F., Maccarrone, M., Borsini, F.

The novel reversible fatty acid amide hydrolase inhibitor ST4070 increases endocannabinoid brain levels and counteracts neuropathic pain in different animal models

(2012) Journal of Pharmacology and Experimental Therapeutics, 342 (1), pp. 188-195.

 

D'Addario, C., Di Francesco, A., Arosio, B., Gussago, C., Dell'Osso, B., Bari, M., Galimberti, D., Scarpini, E., Altamura, A.C., Mari, D., Maccarrone, M.

Epigenetic regulation of Fatty acid amide Hydrolase in Alzheimer disease

(2012) PLoS ONE, 7 (6), art. no. e39186, .

 

D'Addario, C., Dell'Osso, B., Palazzo, M.C., Benatti, B., Lietti, L., Cattaneo, E., Galimberti, D., Fenoglio, C., Cortini, F., Scarpini, E., Arosio, B., Di Francesco, A., Di Benedetto, M., Romualdi, P., Candeletti, S., Mari, D., Bergamaschini, L., Bresolin, N., MacCarrone, M., Altamura, A.C.

Selective DNA methylation of BDNF promoter in bipolar disorder: Differences among patients with BDI and BDII

(2012) Neuropsychopharmacology, 37 (7), pp. 1647-1655.

 

Dainese, E., Sabatucci, A., Angelucci, C.B., Barsacchi, D., Chiarini, M., MacCarrone, M.

Impact of embedded endocannabinoids and their oxygenation by lipoxygenase on membrane properties

(2012) ACS Chemical Neuroscience, 3 (5), pp. 386-392.

 

Battista, N., Meccariello, R., Cobellis, G., Fasano, S., Di Tommaso, M., Pirazzi, V., Konje, J.C., Pierantoni, R., Maccarrone, M.

The role of endocannabinoids in gonadal function and fertility along the evolutionary axis

(2012) Molecular and Cellular Endocrinology, 355 (1), pp. 1-14.

 

Pucci, M., Pasquariello, N., Battista, N., Di Tommaso, M., Rapino, C., Fezza, F., Zuccolo, M., Jourdain, R., Agrò, A.F., Breton, L., Maccarrone, M.

Endocannabinoids stimulate human melanogenesis via type-1 cannabinoid receptor

(2012) Journal of Biological Chemistry, 287 (19), pp. 15466-15478.

 

Battista, N., Meloni, M.A., Bari, M., Mastrangelo, N., Galleri, G., Rapino, C., Dainese, E., Agro, A.F., Pippia, P., Maccarrone, M.

5-Lipoxygenase-dependent apoptosis of human lymphocytes in the International Space Station: Data from the ROALD experiment

(2012) FASEB Journal, 26 (5), pp. 1791-1798.

 

Battista, N., Di Tommaso, M., Bari, M., Maccarrone, M.

The endocannabinoid system: An overview

(2012) Frontiers in Behavioral Neuroscience, (MARCH 2012), pp. 1-7

 

Maccarrone, M., Alexander, S.P.H.

Cannabinoid research in the 2010s

(2012) British Journal of Pharmacology, 165 (8), pp. 2409-2410.

 

Oddi, S., Latini, L., Viscomi, M.T., Bisicchia, E., Molinari, M., Maccarrone, M.

Distinct regulation of nNOS and iNOS by CB 2 receptor in remote delayed neurodegeneration

(2012) Journal of Molecular Medicine, 90 (4), pp. 371-387.

 

Oddi, S., Dainese, E., Sandiford, S., Fezza, F., Lanuti, M., Chiurchiù, V., Totaro, A., Catanzaro, G., Barcaroli, D., De Laurenzi, V., Centonze, D., Mukhopadhyay, S., Selent, J., Howlett, A.C., Maccarrone, M.

Effects of palmitoylation of Cys 415 in helix 8 of the CB 1 cannabinoid receptor on membrane localization and signalling

(2012) British Journal of Pharmacology, 165 (8), pp. 2635-2651.

 

Arosio, B., Bulbarelli, A., Bastias Candia, S., Lonati, E., Mastronardi, L., Romualdi, P., Candeletti, S., Gussago, C., Galimberti, D., Scarpini, E., Dell'Osso, B., Altamura, C., MacCarrone, M., Bergamaschini, L., D'Addario, C., Mari, D.

Pin1 contribution to Alzheimer's disease: Transcriptional and epigenetic mechanisms in patients with late-onset Alzheimer's disease

(2012) Neurodegenerative Diseases, 10 (1-4), pp. 207-211.

 

Bátkai, S., Mukhopadhyay, P., Horváth, B., Rajesh, M., Gao, R.Y., Mahadevan, A., Amere, M., Battista, N., Lichtman, A.H., Gauson, L.A., Maccarrone, M., Pertwee, R.G., Pacher, P.

Δ 8-Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB 2 receptors

(2012) British Journal of Pharmacology, 165 (8), pp. 2450-2461.

 

Den Boon, F.S., Chameau, P., Schaafsma-Zhao, Q., Van Aken, W., Bari, M., Oddi, S., Kruse, C.G., Maccarrone, M., Wadman, W.J., Werkmana, T.R.

Excitability of prefrontal cortical pyramidal neurons is modulated by activation of intracellular type-2 cannabinoid receptors

(2012) Proceedings of the National Academy of Sciences of the United States of America, 109 (9), pp. 3534-3539.

 

Battista, N., Tommaso, M.D., Bari, M., Maccarrone, M.

The endocannabinoid system: An overview

(2012) Frontiers in Behavioral Neuroscience, (FEBRUARY 2012), .

 

Chiurchi, V., MacCarrone, M., Orlacchio, A.

Compositions and methods for treatment of Parkinson's disease: A patent evaluation of WO2011/102847A1

(2012) Expert Opinion on Therapeutic Patents, 22 (2), pp. 181-184.

 

 

Mori, F., Ribolsi, M., Kusayanagi, H., Monteleone, F., Mantovani, V., Buttari, F., Marasco, E., Bernardi, G., Maccarrone, M., Centonze, D.

TRPV1 channels regulate cortical excitability in humans

(2012) Journal of Neuroscience, 32 (3), pp. 873-879.

 

Bernabò, N., Palestini, P., Chiarini, M., Maccarrone, M., Mattioli, M., Barboni, B.

Endocannabinoid-binding CB1 and TRPV1 receptors as modulators of sperm capacitation

(2012) Communicative and Integrative Biology, 5 (1), pp. 68-70

 

Gironi, M., Pasquariello, N., Franchi, S., Pucci, M., Martinelli-Boneschi, F., Solaro, C., Centonze, D., Martino, G., Sacerdote, P., Maccarrone, M.

Comment on "Cannabinoid receptor and N-acyl phosphatidylethanolamine phospholipase D--evidence for altered expression in multiple sclerosis".

(2012) Brain pathology (Zurich, Switzerland), 22 (1), p. 79.

 

Gironi, M., Pasquariello, N., Franchi, S., Pucci, M., Martinelli-Boneschi, F., Solaro, C., Centonze, D., Martino, G., Sacerdote, P., MacCarrone, M.

Letter to the editor

(2012) Brain Pathology, 22 (1), p. 79.

 

Viscomi, M.T., D'Amelio, M., Cavallucci, V., Latini, L., Bisicchia, E., Nazio, F., Fanelli, F., Maccarrone, M., Moreno, S., Cecconi, F., Molinari, M.

Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage

(2012) Autophagy, 8 (2), .

 

Butti, E., Bacigaluppi, M., Rossi, S., Cambiaghi, M., Bari, M., Cebrian Silla, A., Brambilla, E., Musella, A., De Ceglia, R., Teneud, L., De Chiara, V., D'Adamo, P., Garcia-Verdugo, J.M., Comi, G., Muzio, L., Quattrini, A., Leocani, L., MacCarrone, M., Centonze, D., Martino, G.

Subventricular zone neural progenitors protect striatal neurons from glutamatergic excitotoxicity

(2012) Brain, 135 (11), pp. 3320-3335.

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