Prof. MATTIOLI Mauro
Prof. MATTIOLI Mauro

Email: mmattioli@unite.it

Telefono: 0861-266854

Facoltà di appartenenza: BIOSCIENZE E TECNOLOGIE AGRO-ALIMENTARI E AMBIENTALI


 
 
 
 

Curriculum accademico

 
PROF. MAURO MATTIOLI
Mauro Mattioli, nato a Castelfranco E. Modena, il 09.06.1953, sposato con tre figli.

Curriculum vitae 1977 Laurea in Medicina Veterinaria
1978 Ufficiale del Servizio Veterinario Militare dell'esercito italiano
1981 Ricercatore Universitario presso l'Istituto di Fisiologia Veterinaria di Bolonga
1987 Professore Associato In Endocrinologia degli Animali Domestici presso la facoltà di Medicina Veterinaria dell'Università di Bologna
1993 Ordinario di Fisiologia Veterinaria presso la Facoltà di Medicina Veterinaria dell'Università degli Studi di Teramo
1995 Preside della Facoltà di Medicina Veterinaria dell'Università degli Studi di Teramo
1998 Preside della Facoltà di Agraria dell'Università degli Studi di Teramo
1999 Pro-Rettore Vicario dell'Università degli Studi di Teramo

2000 Docente di Fisiologia Veterinaria presso la facoltà di Medicina Veterinaria dell'Università di Bologna

2002 Presidente del corso di laurea in Biotecnologie

2003 Pro-Rettore Vicario dell'Università degli Studi di Teramo

2005 Rettore dell'Università degli Studi di Teramo


Il Prof Mattioli ha sviluppato parte delle sue attività di ricerca presso le seguenti istituzioni Straniere:
· 1981 Ricercatore ospite presso l'Institute of Animal Physiology di Cambridge
· 1982 Ricercatore ospite presso il National Institute for Research in Dayring di Reding 1985 Ricercatore ospite presso l'Animal Research Station di Cambridge
· 1987 Professore associato presso il Dipartimento di Embriologia Molecolare di Cambridge
· 1989 Professore associato presso the Emory University School of Medicine, Atlanta, Georgia,
· 1992 Ricercatore ospite presso l'Istituto di Aquacultura di Stirling, Scozia
· 1994 Professore a contratto presso l'Istituto di Biologia Cellulare del National Research Council del Canada a Ottawa,

L'attività di ricerca del Prof Mattioli si è concentrata prevalentemente nelle seguenti aree di interesse:
· controllo endocrino dell'ovulazione
· meccanismi di trasduzione del segnale delle gonadotropine
· controllo dell'accrescimento follicolare
· oogensi e maturazione della cellula uovo in vitro e in vivo
· meccanismi di riconoscimento dei gameti
· crioconservazione dei gameti
· la maturazione del gamete maschile
· le modificazioni epigenetiche che caratterizzano la transizione da gamete ad embrione
· biologia delle cellule staminali adulte


Essenzialmente le ricerche del Prof Mattioli, concretizzatesi nella pubblicazione di oltre 200 lavori a stampa, si sono concentrate sulle basi fisiologiche della riproduzione con particolare attenzione alla biologia dei gameti.

Curriculum english version

 
PROF. MAURO MATTIOLI
Mauro Mattioli, born in Castelfranco E. Modena, on June 09.1953, married with three children.

Curriculum vitae 1977 Doctor in Veterinary Medicine
1978 Officer of Italian Army in the Veterinary Military Service
1979 Post- graduate fellowship for the study of reproductive physiology in the University of Bologna
1981 University Researcher of the Institute of Animal Physiology, University of Bologna
1987 Associate Professor In Endocrinology of Domestic Animals of the Veterinary School of Medicina University of Bologna
1993 Full Professor of Veterinary Physiology, University of Teramo
1995 Dean of the Veterinary School of Medicine, University of Teramo
1998 Dean of the School of Agriculture, University of Teramo
1999 Vice Rector of the University of Teramo
2000 Professor of Animal Physiology, University of Bologna
2002 President of the Course of Biotechnology, University of Teramo
2003 Vice Rector of the University of Teramo
2005 Rector of the University of Teramo

Research stages in foreign institutions
· 1981 Researcher at the Animal Research Station, Institute of Animal Physiology Cambridge for the study of Luteinizing Horemone receptors in corpora lutea
· 1982 Researcher at the National Institute for Research in Dayring, Reding for the study of PRL receptor in mammary tissues
· 1985 Researcher at the Animal Research Station, Cambridge for the development of in vitro fertilisation in the pig
· 1987 Invited scientist at the Department of Molecular Embryology, Cambridge
· 1989 Invited associate professor at the Emory University School of Medicine, Atlanta, Georgia, to investigate biophysical properties of oocyte membrane
· 1992 Invited associate professor at the Institute of Aquaculture of the University of Stirling, Scotland to investigate the regulation of ovarian activity in teleosts.
· Invited scientist at the Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario,


Prof. Mattioli is presently member of the following societies:
· Italian Society of Veterinary Sciences
· Society For the Study of Fertility
· Society of Developmental Biology
· Italian Society of Physiology

The research activity of Prof. Mattioli has been focussed on the following topics:
· Endocrine control of ovulation
· Signal transduction mechanism of gonadotropins
· Control of follicle growth
· Oogenesis and oocyte maturation in vivo and in vitro
· Mechanisms of sperm-egg recognition
· Gamete cryopreservation
· Sperm maturation, capacitation and function
· DNA epigenetic modifications and gene imprinting at fertilisation and in early embryo development.
· Stem cell biology

Pubblicazioni

 
Role of TRPV1 channels in boar spermatozoa acquisition of fertilizing ability.
Bernabò N, Pistilli MG, Mattioli M, Barboni B.
Mol Cell Endocrinol. 2010 Feb 26. [Epub ahead of print]

Characterization of the methylation status of five imprinted genes in sheep gametes.
Colosimo A, Di Rocco G, Curini V, Russo V, Capacchietti G, Berardinelli P, Mattioli M, Barboni B.
Anim Genet. 2009 Aug 20. [Epub ahead of print]

Fusion as the result of sperm-somatic cell interaction.
Mattioli M, Gloria A, Mauro A, Gioia L, Barboni B.
Reproduction. 2009 Oct;138(4):679-87. Epub 2009 Jul 7.

Three-dimensional microvasculature remodeling study of pig periovulatory follicles using vascular corrosion casts.
Martelli A, Russo V, Palmerini MG, Mauro A, Rinaldi C, Di Giacinto O, Nardinocchi D, Turriani M, Macchiarelli G, Berardinelli P, Mattioli M.
Vet Res Commun. 2009 Sep;33 Suppl 1:97-100. No abstract available.

Lipidic microdomain reorganization during the in vitro capacitation of boar spermatozoa.
Bernabò N, Palestini P, Botto L, Pistilli MG, Falasca G, Gloria A, Mattioli M, Barboni B.
Vet Res Commun. 2009 Sep;33 Suppl 1:81-3. No abstract available.

Factors affecting TRPV1 receptor immunolocalization in boar spermatozoa capacitated in vitro.
Bernabò N, Pistilli MG, Gloria A, Di Pancrazio C, Falasca G, Barboni B, Mattioli M.
Vet Res Commun. 2008 Sep;32 Suppl 1:S103-5. No abstract available.

Role of VEGF in pig preantral follicles.
Martelli A, Russo V, Mauro A, Nardinocchi D, Rinaldi C, Bernabò N, Berardinelli P, Mattioli M.
Vet Res Commun. 2008 Sep;32 Suppl 1:S155-7. No abstract available.

Effect of CB1 receptors on boar sperm plasma membrane.
Pistilli MG, Bernabò N, Gloria A, Mattioli M, Barboni B.
Vet Res Commun. 2007 Aug;31 Suppl 1:189-91. No abstract available.


Meiotic maturation of incompetent prepubertal sheep oocytes is induced by paracrine factor(s) released by gonadotropin-stimulated oocyte-cumulus cell complexes and involves mitogen-activated protein kinase activation.
Cecconi S, Mauro A, Capacchietti G, Berardinelli P, Bernabò N, Di Vincenzo AR, Mattioli M, Barboni B.
Endocrinology. 2008 Jan;149(1):100-7. Epub 2007 Sep 20.

Modifications in chromatin morphology and organization during sheep oogenesis.
Russo V, Martelli A, Berardinelli P, Di Giacinto O, Bernabò N, Fantasia D, Mattioli M, Barboni B.
Microsc Res Tech. 2007 Aug;70(8):733-44.

Effects of 50 Hz extremely low frequency magnetic field on the morphology and function of boar spermatozoa capacitated in vitro.
Bernabò N, Tettamanti E, Pistilli MG, Nardinocchi D, Berardinelli P, Mattioli M, Barboni B.
Theriogenology. 2007 Mar 1;67(4):801-15. Epub 2006 Dec 29.

DNase I activity in pig MII oocytes: implications in transgenesis.
Zannoni A, Spinaci M, Bernardini C, Bacci ML, Seren E, Mattioli M, Forni M.
Reproduction. 2006 Mar;131(3):461-8.

Spatio-temporal analysis of vascular endothelial growth factor expression and blood vessel remodelling in pig ovarian follicles during the periovulatory period.
Martelli A, Berardinelli P, Russo V, Mauro A, Bernabò N, Gioia L, Mattioli M, Barboni B.
J Mol Endocrinol. 2006 Feb;36(1):107-19.

P-type Ca channel activation by membrane depolarisation induces maturation in pig oocytes.
Gioia L, Barboni B, Turriani M, Capacchietti G, Ioannoni A, Lucidi P, Pistilli G, Mattioli M.
Vet Res Commun. 2005 Aug;29 Suppl 2:195-8. No abstract available.




Characterization of the endocannabinoid system in boar spermatozoa and implications for sperm capacitation and acrosome reaction.
Maccarrone M, Barboni B, Paradisi A, Bernabò N, Gasperi V, Pistilli MG, Fezza F, Lucidi P, Mattioli M.
J Cell Sci. 2005 Oct 1;118(Pt 19):4393-404. Epub 2005 Sep 6.

The capability of reprogramming the male chromatin after fertilization is dependent on the quality of oocyte maturation.
Gioia L, Barboni B, Turriani M, Capacchietti G, Pistilli MG, Berardinelli P, Mattioli M.
Reproduction. 2005 Jul;130(1):29-39.

Oocyte maturation is required for correct sperm chromatin rearrangement.
Mattioli M, Gioia L, Turriani M, Capacchietti G, Loi P, Ptak G.
Vet Res Commun. 2004 Aug;28 Suppl 1:205-8.

Maternal chromatin remodeling during maturation and after fertilization in mouse oocytes.
Spinaci M, Seren E, Mattioli M.
Mol Reprod Dev. 2004 Oct;69(2):215-21.

Ovarian follicle vascularization in fasted pig.
Barboni B, Martelli A, Berardinelli P, Russo V, Turriani M, Bernabò N, Lucidi P, Mattioli M.
Theriogenology. 2004 Sep 1;62(5):943-57.

Colocalization of DNA fragmentation and caspase-3 activation during atresia in pig antral follicles.
Berardinelli P, Russo V, Martelli A, Nardinocchi D, Di Giacinto O, Barboni B, Mattioli M.
Anat Histol Embryol. 2004 Feb;33(1):23-7.

In vitro growth of sheep preantral follicles: which perspectives?
Capacchietti G, Cecconi S, Colantoni E, Russo V, Berardinelli P, Barboni B, Mattioli M.
Vet Res Commun. 2003 Sep;27 Suppl 1:583-6. No abstract available.

Paternal chromatin remodelling in mouse oocytes following fertilization.
Spinaci M, Fantinati P, Nicoletti S, Cappannari C, Mattioli M.
Vet Res Commun. 2003 Sep;27 Suppl 1:241-3. No abstract available.

Apoptosis in cooled porcine oocytes: role of calcium (Ca2+) and Ca2+-dependent enzymes.
Barboni B, Mattioli M, Gioia L, Turriani M, Capacchietti G, Lucidi P.
Vet Res Commun. 2003 Sep;27 Suppl 1:203-6. No abstract available.

In vitro growth of preantral follicles isolated from cryopreserved ovine ovarian tissue.
Cecconi S, Capacchietti G, Russo V, Berardinelli P, Mattioli M, Barboni B.
Biol Reprod. 2004 Jan;70(1):12-7. Epub 2003 Sep 3.

Cumulus cells steroidogenesis is influenced by the degree of oocyte maturation.
Lucidi P, Bernabò N, Turriani M, Barboni B, Mattioli M.
Reprod Biol Endocrinol. 2003 May 28;1:45.

Cold-induced calcium elevation triggers DNA fragmentation in immature pig oocytes.
Mattioli M, Barboni B, Gioia L, Loi P.
Mol Reprod Dev. 2003 Jul;65(3):289-97. Erratum in: Mol Reprod Dev. 2003 Sep;66(1):104. Luisa Gioia.

Preovulatory rise of NGF in ovine follicular fluid: possible involvement in the control of oocyte maturation.
Barboni B, Mattioli M, Gioia L, Turriani M, Capacchietti G, Berardinelli P, Bernabò N.
Microsc Res Tech. 2002 Dec 15;59(6):516-21.

Improving delivery and offspring viability of in vitro-produced and cloned sheep embryos.
Ptak G, Clinton M, Tischner M, Barboni B, Mattioli M, Loi P.
Biol Reprod. 2002 Dec;67(6):1719-25.

Follicle activation involves vascular endothelial growth factor production and increased blood vessel extension.
Mattioli M, Barboni B, Turriani M, Galeati G, Zannoni A, Castellani G, Berardinelli P, Scapolo PA.
Biol Reprod. 2001 Oct;65(4):1014-9.

VLA-6 integrin distribution and calcium signalling in capacitated boar sperm.
Barboni B, Lucidi P, Mattioli M, Berardinelli P.
Mol Reprod Dev. 2001 Jul;59(3):322-9.

Ram-induced ovulation to improve artificial insemination efficiency with frozen semen in sheep.
Lucidi P, Barboni B, Mattioli M.
Theriogenology. 2001 Jun 1;55(9):1797-805.

Vascular endothelial growth factor production in growing pig antral follicles.
Barboni B, Turriani M, Galeati G, Spinaci M, Bacci ML, Forni M, Mattioli M.
Biol Reprod. 2000 Sep;63(3):858-64.

Signal transduction mechanism for LH in the cumulus-oocyte complex.
Mattioli M, Barboni B.
Mol Cell Endocrinol. 2000 Mar 30;161(1-2):19-23. Review.

Nerve growth factor production in sheep antral follicles.
Mattioli M, Barboni B, Gioia L, Lucidi P.
Domest Anim Endocrinol. 1999 Nov;17(4):361-71.

In vitro development of sheep preantral follicles.
Cecconi S, Barboni B, Coccia M, Mattioli M.
Biol Reprod. 1999 Mar;60(3):594-601.

Expanded cumuli induce acrosome reaction in boar sperm.
Mattioli M, Lucidi P, Barboni B.
Mol Reprod Dev. 1998 Dec;51(4):445-53.

Calcium elevation in sheep cumulus-oocyte complexes after luteinising hormone stimulation.
Mattioli M, Gioia L, Barboni B.
Mol Reprod Dev. 1998 Jul;50(3):361-9.

Activation of protein kinase A and protein kinase C mediates the depolarising effect of LH in ovine cumulus-corona cells.
Mattioli M, Barboni B, Gioia L.
J Endocrinol. 1996 Sep;150(3):445-56.

Identification of capacitation in boar spermatozoa by chlortetracycline staining.
Mattioli M, Barboni B, Lucidi P, Seren E.
Theriogenology. 1996 Jan 15;45(2):373-81.

Influence of progesterone on boar sperm capacitation.
Barboni B, Mattioli M, Seren E.
J Endocrinol. 1995 Jan;144(1):13-8.

Transduction mechanisms for gonadotrophin-induced oocyte maturation in mammals.
Mattioli M.
Zygote. 1994 Nov;2(4):347-9. Review. No abstract available.

Concentration of cyclic AMP during the maturation of pig oocytes in vivo and in vitro.
Mattioli M, Galeati G, Barboni B, Seren E.
J Reprod Fertil. 1994 Mar;100(2):403-9.

Osmotic and cytotoxic study of vitrification of immature bovine oocytes.
Arav A, Shehu D, Mattioli M.
J Reprod Fertil. 1993 Nov;99(2):353-8.

Actin polymerization in boar spermatozoa: fertilization is reduced with use of cytochalasin D.
Castellani-Ceresa L, Mattioli M, Radaelli G, Barboni B, Brivio MF.
Mol Reprod Dev. 1993 Oct;36(2):203-11.

Calcium and potassium currents in porcine granulosa cells maintained in follicular or monolayer tissue culture.
Mattioli M, Barboni B, DeFelice LJ.
J Membr Biol. 1993 May;134(1):75-83.

Inhibition of Ca2+ and K+ currents by "antifreeze" proteins.
Rubinsky B, Mattioli M, Arav A, Barboni B, Fletcher GL.
Am J Physiol. 1992 Mar;262(3 Pt 2):R542-5.


Luteinizing hormone inhibits potassium outward currents in swine granulosa cells by intracellular calcium mobilization.
Mattioli M, Barboni B, Seren E.
Endocrinology. 1991 Nov;129(5):2740-5.

Changes in maturation-promoting activity in the cytoplasm of pig oocytes throughout maturation.
Mattioli M, Galeati G, Bacci ML, Barboni B.
Mol Reprod Dev. 1991 Oct;30(2):119-25.

Effects of LH and FSH on the maturation of pig oocytes in vitro.
Mattioli M, Bacci ML, Galeati G, Seren E.
Theriogenology. 1991 Jul;36(1):95-105.

Follicle somatic cells influence pig oocyte penetrability and cortical granule distribution.
Galeati G, Modina S, Lauria A, Mattioli M.
Mol Reprod Dev. 1991 May;29(1):40-6.

Cell to cell communication in the cumulus-oocyte complex and cytoplasmic maturation in pig oocytes.
Mattioli M.
Bull Assoc Anat (Nancy). 1991 Mar;75(228):85-8. Review.

The effect of antifreeze glycopeptides on membrane potential changes at hypothermic temperatures.
Rubinsky B, Arav A, Mattioli M, Devries AL.
Biochem Biophys Res Commun. 1990 Dec 31;173(3):1369-74.

Maturation of pig oocytes: observations on membrane potential.
Mattioli M, Barboni B, Bacci ML, Seren E.
Biol Reprod. 1990 Aug;43(2):318-22.

Maturation of pig oocytes in vivo and in vitro.
Moor RM, Mattioli M, Ding J, Nagai T.
J Reprod Fertil Suppl. 1990;40:197-210. Review. No abstract available.

Developmental competence of pig oocytes matured and fertilized in vitro.
Mattioli M, Bacci ML, Galeati G, Seren E.
Theriogenology. 1989 Jun;31(6):1201-7.

Follicular factors influence oocyte fertilizability by modulating the intercellular cooperation between cumulus cells and oocyte.
Mattioli M, Galeati G, Bacci ML, Seren E.
Gamete Res. 1988 Nov;21(3):223-32.

Effect of follicle somatic cells during pig oocyte maturation on egg penetrability and male pronucleus formation.
Mattioli M, Galeati G, Seren E.
Gamete Res. 1988 Jun;20(2):177-83.

Effect of 5alpha-androst-16-en-3-one on oxytocin release in oestrous sows.
Mattioli M, Galeati G, Conte F, Seren E.
Theriogenology. 1986 Mar;25(3):399-403.

Effect of naloxone on plasma concentrations of prolactin and LH in lactating sows.
Mattioli M, Conte F, Galeati G, Seren E.
J Reprod Fertil. 1986 Jan;76(1):167-73.

Effect of PGF-2 alpha on progesterone production in swine luteal cells at different stages of the luteal phase.
Mattioli M, Galeati G, Prandi A, Seren E.
Prostaglandins Leukot Med. 1985 Jan;17(1):43-54.

Androstenedione and testosterone concentrations in plasma and milk of the cow throughout pregnancy.
Gaiani R, Chiesa F, Mattioli M, Nannetti G, Galeati G.
J Reprod Fertil. 1984 Jan;70(1):55-9.

Characteristics of receptors for prostaglandin F-2 alpha in bovine and equine corpora lutea.
Mattioli M, Galeati G, Seren E.
Prostaglandins Leukot Med. 1983 Jul;11(3):259-68.

Concentrations of oestrone sulphate, androgens and LH in the peripheral plasma of mating stallions.
Bono G, Minori D, Gaiani R, Mattioli M.
J Reprod Fertil. 1982 Sep;66(1):17-22. No abstract available.


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Ultimo aggiornamento: 10-06-2019
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