Prof. BARBONETTI Arcangelo
Prof. BARBONETTI Arcangelo

Email: abarbonetti@unite.it

Telefono: -

Facoltà di appartenenza: BIOSCIENZE E TECNOLOGIE AGRO-ALIMENTARI E AMBIENTALI


 
 
 
 

Curriculum accademico

 

Informazioni personali

 

Nome / Cognome

Arcangelo Barbonetti

 

e-mail

arcangelo.barbonetti@univaq.it

Cittadinanza: Italiana

Luogo e Data di nascita

L’Aquila, 31/05/1978

 

 

Settori di competenza

Endocrinologia, Andrologia, Metabolismo

 

Esperienze professionali

Dal 21/12/2018 a oggi

Ricercatore a tempo determinato tipo b Settore Concorsuale 06D2 – Endocrinologia, Nefrologia e Scienze dell’Alimentazione e del Benessere, SSD MED/13 – ENDOCRINOLOGIA (art. 24, comma 3, lett. b) della Legge 30.12.2010 n. 240).

 

Dipartimento di Medicina Clinica, Sanità Pubblica, Scienze della Vita e dell’Ambiente, Università degli Studi di L’Aquila.

Piazzale Salvatore Tommasi 1, 67100 Coppito (AQ).

 

Dal 21/12/2015 al 20/12/2018

Assistente medico di fascia A e, già a partire dal 2012, consulente endocrinologo e andrologo presso la Casa di Cura privata San Raffaele Sulmona (AQ).

 

San Raffaele S.p.A.

Via di Val Cannuta n. 247, 00166 Roma.

 

Dal 10/12/2013 al 09/12/2014

Titolare di contratto di prestazione d’opera professionale per progetto di ricerca:

“individuazione di fattori prognostici clinici, ecografici e seminali sull’efficacia del trattamento del varicocele nel migliorare il potenziale di fertilità maschile”, presso l’U.O.C. di Andrologia Medica dell’ospedale San Salvatore/Università degli Studi di L’Aquila.

 

Dipartimento di Medicina Clinica, Sanità Pubblica, Scienze della Vita e dell’Ambiente, Università degli Studi di L’Aquila.

 

Dal 29/05/2012 al 29/05/2013

Titolare di contratto di prestazione d’opera professionale per progetto di ricerca:

“Valutazione degli effetti della scleroembolizzazione della vena spermatica in soggetti con varicocele sui parametri dell'ecocolor-doppler scrotale e sui parametri seminali”, presso l’U.O.C. di Andrologia Medica dell’ospedale San Salvatore/Università degli Studi di L’Aquila.

 

ASL 1, Avezzano-Sulmona-L’Aquila, ospedale San Salvatore di L’Aquila.

Via Lorenzo Natali 1, 67100 Coppito (AQ).

 

Dal 2010 al 20/12/2018

Attività medica specialistica libero-professionale nel campo dell’endocrinologia ed andrologia

 

 

Attività didattica

Anno Accademico 2019-2020

Insegnamento di Andrologia (SSD: MED/13), modulo del corso integrato di Medicina della Sessualità, Scuola di Specializzazione di Endocrinologia e malattie del metabolismo presso L’Università degli Studi di L’Aquila.

 

Anno Accademico 2019-2020

Insegnamenti di Malattie del Metabolismo (SSD: MED/13) e di Andrologia (SSD: MED/13), CdS in Medicina e chirurgia, Università degli Studi di L’Aquila.

 

Dall’AA 2018-2019 a oggi

Insegnamento di Endocrinologia (SSD: MED/13), CdS in Odontoiatria e protesi dentaria, Università degli Studi di L’Aquila.

 

Anno Accademico

2018-2019

Insegnamento di Endocrinologia (SSD: MED/13), CdS in Dietistica, Università degli Studi di L’Aquila.

 

Anno Accademico

2018-2019

Insegnamenti di Diabetologia e di Ricambio lipidico (SSD: MED/13) per la Scuola di Specializzazione di Endocrinologia e malattie del metabolismo presso L’Università degli Studi di L’Aquila.

 

Anno Accademico

2017-2018

Insegnamento di Clinica del Comportamento Sessuale (SSD: MED/13), Corso di Laurea Magistrale in Psicologia Applicata, Clinica e della Salute, Presso la Facoltà di Psicologia dell’Università degli Studi di L’Aquila.

 

Dall’AA 2017-2018 a oggi

Insegnamento di Andrology II (SSD: MED/04), Corso di Laurea Magistrale in Reproductive Biotechnologies, Facoltà di Bioscienze, Università degli Studi di Teramo.

 

Anno Accademico

2016-2017

Insegnamento di Principi di Endocrinologia e Patologia del Comportamento Sessuale (SSD: MED/13), Corso di Laurea Magistrale in Psicologia Applicata, Clinica e della Salute, Presso la Facoltà di Psicologia dell’Università degli Studi di L’Aquila.

 

Anno Accademico

2016-2017 (dal 9/1 al 30/9/2017)

Insegnamento di Andrology II (SSD: MED/04), Corso di Laurea Magistrale in Reproductive Biotechnologies, Facoltà di Medicina Veterinaria, Università degli Studi di Teramo.

 

Anno Accademico

2011-2012 (dal 22/3 al 12/6/2012)

Insegnamento di Adattamenti e Alterazioni Psico-endocrine (SSD: MED/13) presso la Facoltà di Scienze Motorie dell’Università degli Studi di L’Aquila.

 

Anni Accademici:  

2009-2010 (dal 14/4 al 30/9/2010), 2010-2011 (dal 7/3 al 30/9/2011) e 2011-2012 (dal 10/1 al 30/09/2012)

Insegnamento di Andrologia II, modulo Tecniche Applicate (SSD: MED/13), Corso di Laurea in Biotecnologie della Riproduzione presso la Facoltà di Medicine Veterinaria dell’Università degli Studi di Teramo.

 

 

Istruzione e formazione

 

2008-2012 – Dottorato di Ricerca in Medicina Interna ed Immunologia Applicata, XXIV ciclo con progetto in ambito andrologico, conseguito in data 06/04/2012 con discussione di una tesi dal titolo: “Metabolismo energetico dello spermatozoo umano: dal modello biochimico del sistema endocannabinoide al modello clinico del paziente mieloleso”.

 

2003-2008 – Specializzazione in Endocrinologia e Malattie del Ricambio conseguita in data 02/12/2008 con votazione di 50/50 e Lode.

 

22/01/2004 - Abilitazione all'esercizio della professione di medico chirurgo.

 

1997-2003 – Corso di Laurea in Medicina e Chirurgia (Diploma di Laurea conseguito in data 21/10/2003 con votazione di 110/110 e Lode).

 

 

Università degli Studi di L’Aquila

Livello di classificazione

nazionale o internazionale

ISCED8

 

 

05/04/2017

Conseguimento dell’Abilitazione Scientifica Nazionale alle funzioni di Professore Universitario di Seconda fascia, settore concorsuale 06/D2 (Endocrinologia, Nefrologia e Scienze della Alimentazione e del Benessere): https://asn16.cineca.it/pubblico/miur/esito-abilitato/06%252FD2/2/1

 

29/09/2010

Conseguimento del titolo di Clinical Andrologist rilasciato dalla European Academy of Andrology (EAA) a conclusione dei previsti 7 anni di training presso l’EAA center di L’Aquila (U.O.C. di Andrologia Medica dell’ospedale San Salvatore/Università degli Studi di L’Aquila).

 

Attività di ricerca clinica e di base:

Dal 2003 svolge attività di ricerca nell’ambito della fisiopatologia della riproduzione e dal 2009 si occupa di ricerca in campo andrologico ed endocrinologico nel paziente con lesione midollare. l principali campi di interesse sono rappresentati da: meccanismi molecolari dell’acquisizione nemaspermica della capacità fecondante, infertilità immunologica maschile, ruolo del sistema endocannabinoide nelle funzioni/disfunzioni nemaspermiche, metabolismo energetico dello spermatozoo umano, fisiopatologia delle anomalie seminali del mieloleso ed in corso di flogosi/infezioni delle vie seminali, disordini sessuologici e connessi alla carenza androgenica nel paziente con mielolesione, studio dei mediatori del rischio cardiovascolare in soggetti con disfunzione erettile, ruolo della diagnostica ecografica andrologica nel work-up dell’infertilità maschile.

 

Premi:

·  Best Oral Presentation al 12th Congresso Nazionale della Società Italiana di Andrologia e Medicina della Sessualità (SIAMS), tenuto a Roma, dal 1 al 3 Dicembre 2016, per lo studio: ‘In vitro exposure of human spermatozoa to bisphenol A induces a pro-oxidative and apoptotic mitochondrial dysfunction’.

·  Best Poster Presentation al 7th European Congress of Andrology (ECA), tenuto a Berlino, dal 28 Novembre al 1 Dicembre 2012, per lo studio: ‘Asthenozoospermia in spinal cord-injured men: a model for shedding light upon the contribution of glycolysis and mitochondrion in supporting sperm motility’.

·  Best Poster Presentation al 10th Congresso Nazionale della Società Italiana di Andrologia e Medicina della Sessualità (SIAMS), tenuto a Lecce, dal 15 al 17 Novembre 2012, per lo studio: ‘Protective effect of probiotic lactobacilli against sperm damage exerted by soluble factors from Escherichia coli: focus on lipopolysaccharide’.

·  Migliore studio clinico al Convegno nazionale CNOPUS, tenuto ad Assisi, dal 12 al 14 Novembre 2015 per lo studio: ‘Low testosterone leves are independently associated with non-alcoholic fatty liver disease in men with chronic spinal cord injury’.

 

Partecipazione a Collegio dei Docenti di corso di Dottorato:

Partecipazione al Collegio dei Docenti del corso di Dottorato in BIOTECNOLOGIE CELLULARI E MOLECOLARI (DOT13A8025) presso l’Università degli Studi di Teramo dall’AA 2020-2021. Coordinatore: Prof. Barbara Barboni.

 

Membro delle seguenti Società:

·       Società Italiana di Endocrinologia (SIE) dal 2006. Eletto nel 2015 componente del Comitato di Coordinamento Regionale SIE Abruzzo con ruolo di segretario – tesoriere.

·       Società Italiana di Andrologia e Medicina della Sessualità (SIAMS) dal 2009, con ruolo di Coordinatore del Comitato Newsletter per i bienni 2013-2014 e 2015-2016, Segretario Regionale per l’Abruzzo per il biennio 2017-2018 e 2019-2020, Coordinatore della Commissione Aggiornamento Clinico-Scientifico per il biennio 2017-2018 e Membro della Commissione Scientifica per il biennio 2015-2016 e per il biennio 2019-2020. Attualmente Responsabile del progetto Klinefelter ItaliaN Group (KING) del centro SIAMS di L’Aquila.

·       Società Italiana Midollo Spinale (SIMS), dal 2012.

·       European Academy of Andrology (EAA): affiliated member dal 2015.

 

Partecipazione a progetti di ricerca nazionali (nel gruppo dell’U.O.C. di Andrologia Medica dell’Università di L’Aquila):

·  PRIN 2004: ‘Effetto di modulatori farmacologici della motilità nemaspermica sulla capacità fecondante dello spermatozoo umano”- “Molecular mechanisms of sperm motility’.

·  PRIN 2005: ‘Meccanismi molecolari di regolazione della funzione spermatica e loro alterazioni’.

·  PRIN 2006: ‘Sistema endocannabinoide nell’acquisizione della capacità fecondante dello spermatozoo umano e nella sub-fertilità maschile’.

·  PRIN 2009: ‘Meccanismi di danno al DNA nemaspermico: aspetti molecolari e nuove prospettive cliniche’.

·  Studio clinico “Prevalenza della adiposità intRa-addOMInale e della SindromE metabolica nel DIAbete mellito di tipo 2 – PROMISE DIA”; Prot. n° RIMON_L_00019 (1/1/2006 - 30/6/2006).

 

Referee delle riviste:

The Journal of Clinical Endocrinology and Metabolism; Frontiers in Endocrinology; Andrology; The Journal of Sexual Medicine; Sexual Medicine; Journal of Clinical Medicine; Reproduction; Journal of Neurotrauma; Archives of Physical Medicine and Rehabilitation; The Journal of Spinal Cord Medicine; European Journal of Applied Physiology; Chemico-Biological Interactions; International Journal of Molecular Sciences; Nutrients; Cannabis and Cannabinoid Research; Health & Social Care in the Community; Therapeutic Advances in Reproductive Health; The Journal of Functional Foods; Environmental Pollution.

 

Attività editoriali:

·        Dal 12/09/2016 al 01/01/2018 membro dell’Editorial Board della rivista Elsevier: ‘New Horizons in Clinical Case Reports’ (NHCCR, ISSN: 2352-9482), giornale ufficiale della European Society for Translational Medicine (EUSTM).

·       Attualmente Guest Associate Editor di Frontiers in Endocrinology (IF 3.675) per il research topic: “Bisphenols and Male Reproductive Health” (https://www.frontiersin.org/research-topics/11230/bisphenols-and-male-reproductive-health#overview).

·       Attualmente Guest Associate Editor di Journal of Clinical Medicine (IF 5.688) per lo special issue: ‘Erectile Dysfunction in Men with Chronic Diseases: from Pathophysiology to Clinical Management’ (https://www.mdpi.com/journal/jcm/special_issues/Erectile_Dysfunction).

 

Pubblicazioni internazionali peer-reviewed

 

1.       Barbonetti A, Zugaro A, Sciarretta F, Santucci R, Necozione S, Ruvolo G, Francavilla S, Francavilla F. The inhibition of the human sperm phosphatidylinosytol 3-kinase by LY294002 does not interfere with sperm/oocyte interaction. Int J Androl 2006;29(4):468-74.

2.       Francavilla F, Barbonetti A, Necozione S, Santucci R, Cordeschi G, Macerola B, Francavilla S. Within-subject variation of seminal parameters in men with infertile marriages. Int J Androl 2007;30(3):174-81.

3.       Francavilla F, Santucci R, Barbonetti A, Francavilla S. Naturally-occurring antisperm antibodies in men: interference with fertility and clinical implications. An update. Front Biosci 2007;12:2890-911.

4.       Zugaro A, Pandolfi C, Barbonetti A, Vassallo MR, D'Angeli A, Necozione S, Colangeli MS, Francavilla S, Francavilla F. Retinol binding protein 4, low birth weight-related insulin resistance and hormonal contraception. Endocrine 2007;32(2):166-9.

5.       Barbonetti A, Vassallo MRC, Antonangelo C, Nuccetelli V, D’Angeli A, Pelliccione F, Giorgi M, Francavilla F, Francavilla S. RANTES (Regulated on Activation Normal T Expressed and Secreted chemokine) and human sperm fertilizing ability: effect on acrosome reaction and sperm/oocyte fusion. Mol Hum Reprod 2008;14(7):387-91.

6.       Pandolfi C, Zugaro A, Lattanzio F, Necozione S, Barbonetti A, Colangeli MS, Francavilla S, Francavilla F. Low birth weight and later development of insulin resistance and biochemical/clinical features of polycystic ovary syndrome. Metabolism 2008;57(7):999-1004.

7.       Barbonetti A, Vassallo MRC, Cinque B, Antonangelo C, Sciarretta F, Santucci R, D’Angeli A, Francavilla S, Francavilla F. Dynamics of the global tyrosine phosphorylation during capacitation and acquisition of the ability to fuse with oocytes in human spermatozoa. Biol Reprod 2008;79(4):649-56.

8.       Francavilla F, Sciarretta F, Sorgentone S, Necozione S, Santucci R, Barbonetti A, Francavilla S. Intrauterine insemination with or without mild ovarian stimulation in couples with male subfertility due to oligo/astheno- and/or teratozoospermia or antisperm antibodies: a prospective cross-over trial. Fertil Steril 2009;92(3):1009-11.

9.       Francavilla F, Battista N, Barbonetti A, Vassallo MR, Rapino C, Antonangelo C, Pasquariello N, Catanzaro G, Barboni B, Maccarrone M. Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability. Endocrinology 2009;150(10):4692-700.

10.     Barbonetti A, Vassallo MR, Pelliccione F, D'Angeli A, Santucci R, Muciaccia B, Stefanini M, Francavilla F, Francavilla S. Beta-chemokine receptor CCR5 in human spermatozoa and its relationship with seminal parameters. Hum Reprod 2009;24(12):2979-87.

11.    Barbonetti A, Vassallo MRC, Cordeschi G, Venetis D, Carboni A, Sperandio A, Felzani G, Francavilla S, Francavilla F. Protein tyrosine phosphorylation of the human sperm head during capacitation: immunolocalization and relationship with acquisition of sperm-fertilizing ability. Asian J Androl 2010;12(6):853-61.

12.    Barbonetti A, Vassallo MRC, Fortunato D, Francavilla S, Maccarrone M, Francavilla F. Energetic metabolism and human sperm motility: impact of CB1 receptor activation. Endocrinology 2010; 151(12):5882-92.

13.    Barbonetti A, Cinque B, Vassallo MRC, Mineo S, Francavilla S, Cifone MG, Francavilla F. Effect of vaginal probiotic lactobacilli on in vitro induced sperm lipid peroxidation and its impact on sperm motility and viability. Fertil Steril 2011;95(8):2485-8.

14.    Barbonetti A, Cavallo F, Felzani G, Francavilla S, Francavilla F. Erectile dysfunction is the main determinant of psychological distress in men with spinal cord injury. J Sex Med 2012;9(3):830-6.

15.    Pelliccione F, D’Angeli A, Filipponi S, Falone S, Necozione S, Barbonetti A, Francavilla F, Francavilla S. Serum from patients with erectile dysfunction inhibits circulating angiogenic cells from healthy men: relationship with cardiovascular risk, endothelial damage and circulating angiogenic modulators. Int J Androl 2012;35(5):645-52. 

 

16.    Pezzella A, Barbonetti A, Micillo A, D’Andrea S, Necozione S, Gandini L, Lenzi A, Francavilla F, Francavilla S. Ultrasonoghraphic determination of caput epididymidis diameter is strongly predictive of obstruction in the genital tract in azoospermic men with normal serum FSH. Andrology 2013;1(1):133-8.

17.    Barbonetti A, Vassallo MRC, Di Rosa A, Leombruni Y, Felzani G, Gandini L, Lenzi A, Necozione S, Francavilla S, Francavilla F. Involvement of mitochondrial dysfunction in the adverse effect exerted by seminal plasma from men with spinal cord injury on sperm motility. Andrology 2013; 1(3):456-63.

18.    Barbonetti A, Vassallo MRC, Cinque B, Filipponi S, Mastromarino P, Cifone MG, Francavilla S, Francavilla F.  Soluble products of Escherichia coli induce mitochondrial dysfunction-related sperm membrane lipid peroxidation which is prevented by lactobacilli. PLoS ONE 2013;8(12):e83136.

19.    Pelliccione F, D’Angeli A, D’Andrea S, Barbonetti A, Pezzella A, Necozione S, Falone S, Amicarelli F, Francavilla F, Francavilla S. Tadalafil treatment had a modest effect on endothelial cell damage and repair ability markers in men with erectile dysfunction and vascular risk. Asian J Androl 2014;16(2):290-4.

20.    Barbonetti A, Vassallo MR, Costanzo M, Battista N, Maccarrone M, Francavilla S, Francavilla F. Involvement of cannabinoid receptor-1 activation in mitochondrial depolarizing effect of lipopolysaccharide in human spermatozoa. Andrology 2014;2(4):502-9.

21.    Pezzella A, Barbonetti A, D'Andrea S, Necozione S, Micillo A, Di Gregorio A, Francavilla F, Francavilla S. Ultrasonographic caput epididymis diameter is reduced in non-obstructive azoospermia compared with normozoospermia but is not predictive for successful sperm retrieval after TESE. Hum Reprod 2014;29(7):1368-74.

22.    Barbonetti A, Vassallo MRC, Pacca F, Cavallo F, Costanzo M, Felzani G, Francavilla S, Francavilla F. Correlates of low testosterone in men with chronic spinal cord injury. Andrology 2014;2(5):721-8.

23.    Mastromarino P, Hemalatha R, Barbonetti A, Cinque B, Cifone MG, Tammaro F, Francavilla F. Biological control of vaginosis to improve reproductive health. Indian J Med Res 2014;140 Suppl:S91-7.

24.    Francavilla F, Barbonetti A. Letter to the Editor: Comment on Gaspar AP, Brandão CM, Lazaretti-Castro M. Bone mass and hormone analysis in spinal cord injury patients: evidences for a gonadal axis disruption. J Clin Endocrinol Metab 2015;100(2):L20.

25.    D'Andrea S, Giordano AV, Carducci S, Sacchetti L, Necozione S, Costanzo M, De Gregorio A, Micillo A, Francavilla F, Francavilla S, Barbonetti A. Embolization of left spermatic vein in non-obstructive azoospermic men with varicocele: role of FSH to predict the appearance of ejaculated spermatozoa after treatment. J Endocrinol Invest 2015;38(7):785-90.

26.    Barbonetti A, Vassallo MR, Felzani G, Francavilla S, Francavilla F. Association between 25(OH)-vitamin D and testosterone levels: evidence from men with chronic spinal cord injury. J Spinal Cord Med 2016;39(3):246-52.

27.    Barbonetti A, Caterina Vassallo MR, Cotugno M, Felzani G, Francavilla S, Francavilla F. Low testosterone and non-alcoholic fatty liver disease: Evidence for their independent association in men with chronic spinal cord injury. J Spinal Cord Med 2016;39(4):443-9.

28.    Barbonetti A, Sperandio A, Micillo A, D'Andrea S, Pacca F, Felzani G, Francavilla S, Francavilla F. Independent Association of Vitamin D With Physical Function in People With Chronic Spinal Cord Injury. Arch Phys Med Rehabil 2016;97(5):726-32.

29.    Micillo A, Vassallo MR, Cordeschi G, D'Andrea S, Necozione S, Francavilla F, Francavilla S, Barbonetti A. Semen leukocytes and oxidative-dependent DNA damage of spermatozoa in male partners of subfertile couples with no symptoms of genital tract infection. Andrology 2016;4(5):808-15.

30.    D’Andrea S, Micillo A, Francavilla F, Di Emidio G, Tatone C, Francavilla S, Barbonetti A. Serum from patients with erectile dysfunction and vascular risk factors triggered an oxidative stress-dependent mitochondrial apoptotic pathway in ex vivo expanded circulating angiogenic cells of healthy men. J Sex Med 2016;13(7):1063-70.   

31.    Barbonetti A, Castellini C, Di Giammarco N, Santilli G, Francavilla S, Francavilla F. In vitro exposure of human spermatozoa to bisphenol A induces pro-oxidative/apoptotic mitochondrial dysfunction. Reprod Toxicol 2016;66:61-7. 

32.    Barbonetti A, Bisogno T, Battista N, Piscitelli F, Micillo A, Francavilla S, Maccarrone M, Francavilla F. 2-arachidonoylglycerol levels are increased in leukocytospermia and correlate with seminal macrophages. Andrology 2017;5(1):87-94.

33.    Barbonetti A, Cavallo F, D'Andrea S, Muselli M, Felzani G, Francavilla S, Francavilla F. Lower Vitamin D Levels Are Associated With Depression in People With Chronic Spinal Cord Injury. Arch Phys Med Rehabil 2017;98(5):940-6.

34.    D'Andrea S, Micillo A, Barbonetti A, Giordano AV, Carducci S, Mancini A, Necozione S, Francavilla F, Francavilla S. Determination of spermatic vein reflux after varicocele repair helps to define the efficacy of treatment in improving sperm parameters of subfertile men. J Endocrinol Invest 2017;40(10):1145-53.

35.    Barbonetti A, D'Andrea S, Martorella A, Felzani G, Francavilla S, Francavilla F. Low vitamin D levels are independent predictors of 1-year worsening in physical function in people with chronic spinal cord injury: a longitudinal study. Spinal Cord 2018;56(5):494-501.

36.    Barbonetti A, Calogero AE, Balercia G, Garolla A, Krausz C, La Vignera S, Lombardo F, Jannini EA, Maggi M, Lenzi A, Foresta C, Ferlin A. The use of follicle stimulating hormone (FSH) for the treatment of the infertile man: position statement from the Italian Society of Andrology and Sexual Medicine (SIAMS). J Endocrinol Invest 2018;41(9):1107-1122.

37.    Tatone C, Di Emidio G, Barbonetti A, Carta G, Luciano AM, Falone S, Amicarelli F. Sirtuins in gamete biology and reproductive physiology: emerging roles and therapeutic potential in female and male infertility. Hum Reprod Update 2018;24(3):267-89.

38.    Barbonetti A, D'Andrea S, Samavat J, Martorella A, Felzani G, Francavilla S, Luconi M, Francavilla F. Can the positive association of osteocalcin with testosterone be unmasked when the preeminent hypothalamic-pituitary regulation of testosterone production is impaired? The model of spinal cord injury. J Endocrinol Invest 2019;42(2):167-173.

39.    Vezzani S, Giannetta E, Altieri B, Barbonetti A, Bellastella G, Certo R, Cignarelli A, Cinti F, D'Andrea S, Di Dalmazi G, Frara S, Garelli S, Giuffrida G, Maiorino MI, Mele C, Mezza T, Pani MG, Samà MT, Satta C, Santi D. An italian survey of compliance with major guidelines for L-thyroxine of primary hypothyroidism. Endocr Pract 2018;24(5):419-28.

40.    Barbonetti A, D'Andrea S, Martorella A, Felzani G, Francavilla S, Francavilla F. Risk of prostate cancer in men with spinal cord injury: A systematic review and meta-analysis. Asian J Androl 2018;20(6):555-560.

41.    D'Andrea S, Barbonetti A, Castellini C, Martorella A, Minaldi E, Viktor Giordano A, Carducci S, Necozione S, Francavilla F, Francavilla S. Reproductive hormones and sperm parameters after varicocele repair: An observational study. Andrologia 2018;50(10):e13118.

42.    D'Andrea S, Barbonetti A, Martorella A, Necozione S, Francavilla F, Francavilla S. Effect of prolonged treatment with phosphodiesterase-5-inhibitors on endothelial dysfunction in vascular diseases and vascular risk conditions: A systematic review analysis and meta-analysis of randomized double-blind placebo-controlled trials. Int J Clin Pract 2019;73(2):e13296.

43.    Guadagni V, Sarà M, Conson M, Carolei A, Sacco S, Vadini S, Pistarini C, Barbonetti A, Iaria G, Pistoia F. Cognitive and Emotional Empathy in Individuals with Spinal Cord Injury. Behav Neurol 2019;2019:1312934.

44.    Barbonetti A, D'Andrea S, Cavallo F, Martorella A, Francavilla S, Francavilla F. Erectile Dysfunction and Premature Ejaculation in Homosexual and Heterosexual Men: A Systematic Review and Meta-Analysis of Comparative Studies. J Sex Med 2019;16(5):624-632.

45.    Barbonetti A, Castellini C, D'Andrea S, Cordeschi G, Santucci R, Francavilla S, Francavilla F. Prevalence of anti-sperm antibodies and relationship of degree of sperm auto-immunization to semen parameters and post-coital test outcome: a retrospective analysis of over 10 000 men. Hum Reprod 2019;34(5):834-841.     

46.    Barbonetti A, Martorella A, Minaldi E, D'Andrea S, Bardhi D, Castellini C,Francavilla F, Francavilla S. Testicular Cancer in Infertile Men With and Without Testicular Microlithiasis: A Systematic Review and Meta-Analysis of Case-Control Studies. Front Endocrinol (Lausanne) 2019;10:164. doi:10.3389/fendo.2019.00164. eCollection 2019.

47.    D'Andrea S, Barbonetti A, Castellini C, Nolletti L, Martorella A, Minaldi E,Giordano AV, Carducci S, Necozione S, Francavilla F, Francavilla S. Left spermatic vein reflux after varicocele repair predicts pregnancies and live births in subfertile couples. J Endocrinol Invest 2019;42(10):1215-1221.

48.    Castellini C, D’Andrea S, Martorella A, Minaldi E, Necozione S, Francavilla F, Francavilla S, Barbonetti A. Relationship between leukocytospermia, reproductive potential after assisted reproductive technology, and sperm parameters: a systematic review and meta-analysis of case-control studies. Andrology 2020;;8(1):125-135.

49.    Minaldi E, D'Andrea S, Castellini C, Martorella A, Francavilla F, Francavilla S, Barbonetti A. Thyroid autoimmunity and risk of post-partum depression: a systematic review and meta-analysis of longitudinal studies. J Endocrinol Invest 2020;43(3):271-277.

50.    D'Andrea S, Pallotti F, Senofonte G, Castellini C, Paoli D, Lombardo F, Lenzi A, Francavilla S, Francavilla F, Barbonetti A. Polymorphic Cytosine-Adenine-Guanine Repeat Length of Androgen Receptor Gene and Gender Incongruence in Trans Women: A Systematic Review and Meta-Analysis of Case-Control Studies. J Sex Med 2020;17(3):543-550.

51.    D'Andrea S, Castellini C, Paladino V, Totaro M, Felzani G, Francavilla S, Francavilla F, Barbonetti A. Metabolic syndrome is the key determinant of impaired vaginal lubrication in women with chronic spinal cord injury. J Endocrinol Invest 2020 Jan 25. doi: 10.1007/s40618-020-01185-w.

52.    Barbonetti A, D'Andrea S, Francavilla S. Testosterone replacement therapy. Andrology 2020 Feb 18. doi: 10.1111/andr.12774.

53.    D'Andrea S, Minaldi E, Castellini C, Cavallo F, Felzani G, Francavilla S, Francavilla F, Barbonetti A. Independent Association of Erectile Dysfunction and Low Testosterone Levels With Life Dissatisfaction in Men With Chronic Spinal Cord Injury. J Sex Med 2020 Feb 20. doi: 10.1016/j.jsxm.2020.01.018.

54.    D'Andrea S, Castellini C, Minaldi E, Totaro M, Felzani G, Francavilla S, Francavilla F, Barbonetti A. Testosterone, level of the lesion and age are independently associated with prostate volume in men with chronic spinal cord injury. J Endocrinol Invest 2020 Apr 4. doi: 10.1007/s40618-020-01243-3.

55.    D'Andrea S, Spaggiari G, Barbonetti A, Santi D. Endogenous transient doping: physical exercise acutely increases testosterone levels-results from a meta-analysis. J Endocrinol Invest 2020 Apr 15. doi: 10.1007/s40618-020-01251-3.

56.    Lotti F, Frizza F, Balercia G, Barbonetti A, Behre HM, Calogero AE, Cremers JF, Francavilla F, Isidori AM, Kliesch S, La Vignera S, Lenzi A, Marcou M, Pilatz A, Poolamets O, Punab M, Peraza Godoy MF, Rajmil O, Salvio G, Shaeer O, Weidner W, Maseroli E, Cipriani S, Baldi E, Degl'Innocenti S, Danza G, Caldini AL, Terreni A, Boni L, Krausz C, Maggi M. The European Academy of Andrology (EAA) ultrasound study on healthy, fertile men: clinical, seminal and biochemical characteristics. Andrology 2020 Apr 30. doi: 10.1111/andr.12808.

57.    Barbonetti A, Castellini C, D'Andrea S, Minaldi E, Totaro M, Francavilla S, Francavilla F. Relationship between natural and intrauterine insemination-assisted live births and the degree of sperm autoimmunisation. Hum Reprod 2020 May 2. pii: deaa070. doi: 10.1093/humrep/deaa070. 

 

Altre pubblicazioni

 

1.        Santucci R, Barbonetti A, Necozione S, Francavilla F. Valutazione dei trattamenti dell’ipofertilità idiopatica maschile: quale end-point? Foresta C. (ed). La riproduzione umana e le influenze ambientali, Libraria Editrice Università di Padova, 2006: pp. 61-68.

2.        Barbonetti A, Sciarretta F, Francavilla F. Fisiopatologia iatrogena. Lenzi A., Jannini E.A., Maggi M. (eds). Trattato di sessuologia medica, Elsevier Masson, 2007; Cap. 59 (impotenza): pp. 291-298.

3.        Francavilla F, Barbonetti A. Male Autoimmune Infertility. In: WKH Krause and RK Naz (eds.), Immune Infertility, ©Springer Verlag Berlin Heidelberg, 2009: pp. 145-153.

4.        Francavilla F, Barbonetti A. Infertilità. Attanasio R., Castello R., Dorizzi R., Ferone D., Giagulli V., Lenzi A., Martinelli M., Toscano V., Valentini F., Valota M. (eds.), Diagnostica in Endocrinologia Clinica – Manuale per valutazione e inquadramento delle patologie gonadiche, Scripta s.c. press., Verona, 2009: pp. 143-155; 311-313.

5.        Barbonetti A, Cordeschi G, Francavilla F. Indicazione e metodi di crioconservazione degli spermatozoi. Foresta C., Ferlin A., Lenzi A., Garolla A. (eds), La medicina della riproduzione dalla sperimentazione alla clinica, CLEUPS S.c. Libraria Editrice Università di Padova, 2011: pp. 315-319.

6.        Barbonetti A, Francavilla F. Biochimica del liquido seminale. Lenzi A., Foresta C., Jannini E.A., Maggi M. (eds), Guida allo studio dell’andrologia, Società Editrice Universo, 2012; Cap. 9: pp. 65-70.

7.        Francavilla F, Barbonetti A. Infertility: Immunological Aspects. 2012; In: eLS. John Wiley & Sons, Ltd: Chichester. DOI: 10.1002/978047001 5902.a0000967. pub2. www.els.net.

8.        Francavilla F, Barbonetti A. Male Autoimmune Infertility. In: WKH Krause & RK Naz (eds.): Immune infertility: Impact of Immune Reactions on Human Fertility. Second Edition. ©Springer Verlag Berlin Heidelberg, 2017: pp. 187-196.

9.        Barbonetti A, Sciarretta F, Francavilla F. Fisiopatologia iatrogena. EA Jannini, A Lenzi, M Maggi (eds). Sessuologia medica. Trattato di psicosessuologia, medicina della sessualità e salute della coppia, Seconda edizione. Edra S.p.A., Milano, 2017; Cap. 61 (Patologia dell’erezione): pp. 308-316.

10.     Ciocca G, Zauri S, Limoncin E, Mollaioli D, Niolu C, Bianciardi E, Siracusano A, D'Andrea S, Barbonetti A, Jannini EA. Psicoendocrinologia e psicopatologia delle transizioni di genere. Noos 2018;24(3):135-141. DOI: 10.1722/3152.31323.

11.     Francavilla F, Barbonetti A, D’Andrea S, Francavilla S. Diagnostica e approccio terapeutico della induratio penis plastica. L'Endocrinologo 2019;20:33. https://doi.org/10.1007/s40619-019-00518-z.

        

Relazioni su invito e moderazioni in convegni e congressi nazionali

 

·  Corso di aggiornamento nazionale: “La sindrome di Klinefelter: la forma classica e le sue varianti” (Convegno KING 2.0). Discussant nella sessione: “Complicanze cliniche II”, Napoli, 25-26 Ottobre 2019.

·  XXXIV Convegno di Medicina della Riproduzione. Denatalità e ipofertilità: quale ruolo per l’ambiente. Discussant nella sessione: “Terapia delle Insufficienze gonadiche”, Abano (PD), 01-02 Marzo 2019.

·  Identità sessuali: il senso di Sé oltre il pregiudizio e la sofferenza. Presentazione di una relazione dal titolo: “Neuroendocrinobiologia dell’identità transessuale”, L’Aquila, 9 Novembre 2018.

·  XIII Congresso Nazionale della Società Italiana Andrologia e Medicina della Sessualità (SIAMS). Presentazione dal titolo: “Il trattamento con FSH nel maschio con infertilità idiopatica”, Catania, 25-27 Ottobre 2018.

·  Personalizzazione dei percorsi diagnostici e terapeutici: una visione d’insieme. Presentazione di una relazione dal titolo: “Infertilità immunologica maschile e trattamento farmacologico”, Sora (FR), 26 maggio 2018. 

·  IIEM (Incontri Italiani di Endocrinologia e Metabolismo) della Società Italiana di Endocrinologia (SIE)’, Presentazione di una relazione dal titolo: “Nuove linee guida nella diagnosi di ipogonadismo: revisione critica”, Bari, 10-11 maggio 2018.

·  XXXIII Convegno di Medicina della Riproduzione. Denatalità e riproduzione: traiettorie convergenti. Presentazione di una relazione dal titolo: “Ipogonadismo ipogonadotropo e terapia con FSH nel maschio”, Abano (PD), 23-24 Febbraio 2018.

·  I Congresso Nazionale Androyoung, Società Italiana Andrologia e Medicina della Sessualità (SIAMS). Moderatore della presentazione dal titolo: “La terapia con FSH nell’infertilità maschile”. Rimini, 17-18 Novembre 2017. 

·  Responsabile scientifico del corso di aggiornamento: La sessualità nell’uomo fragile. Sulmona (AQ), 21 Ottobre 2017, con presentazione di una relazione dal titolo: “disfuzioni sessuali nell’uomo fragile”.

·  II Convegno Nazionale Città di Sulmona. Presentazione di una relazione dal titolo: “Bisfenoli e fertilità maschile”, Sulmona (AQ), 10-11 Aprile 2015.

·  Endo Games 2015. Presentazione di un caso clinico interattivo sull’ipogonadismo dell’adulto, Chieti, 19-21 Febbraio 2015.

·  XI Congresso Nazionale della Società Italiana Andrologia e Medicina della Sessualità (SIAMS). Presentazione di una relazione dal titolo: “Sessualità e ipogonadismo nell’uomo fragile: paziente con lesione midollare”, Cagliari, 13-15 Novembre 2014.

·  XXX Congresso Nazionale ANASMES (Associazione Nazionale Specialisti in Medicina dello Sport). Presentazione di una relazione dal titolo: “Performance e carenza androgenica: il modello del paziente mieloleso”, Chieti, 29-31 Maggio – 01 Giugno 2014.

·  Il dolore nel paziente con lesione del midollo spinale. Corso ECM organizzato dal San Raffaele Sulmona. Presentazione di una relazione dal titolo: “Terapia farmacologica”. Sulmona (AQ), 30 Dicembre 2013

·  Giornate Endocrinologiche Abruzzesi (GEA) 2013. Presentazione di una relazione dal titolo: “Terapia sostitutiva nel maschio”. Teramo, 17-18 Maggio 2013.

·  Problematiche sessuali e riproduttive nella disabilità neuromotoria. Corso ECM organizzato dal San Raffaele Sulmona. Presentazione di una relazione dal titolo: “Distress psicologico nei mielolesi con o senza disfunzione erettile: dati dal San Raffaele Sulmona”. Sulmona (AQ), 14 Novembre 2012.

·  La disreflessia autonomica nel paziente con lesione midollare. Corso ECM organizzato dal San Raffaele Sulmona. Presentazione di una relazione sul sistema riproduttivo. Sulmona (AQ), 26 Settembre 2012.

·  Giornate Endocrinologiche Abruzzesi (GEA) 2012. Presentazione di una relazione dal titolo: “Ipogonadismo nel paziente internistico: condizione da trattare?”. Lanciano (CH), 8-9 Giugno 2012.

·  La fertilità tra biologia e cultura. Presentazione di una relazione dal titolo: “Possibilità terapeutiche per l’uomo infertile”. Teramo, 18 Maggio, 2012.

·  Problematiche endocrinologiche dal concepimento all’età adulta. Presentazione di una relazione dal titolo: “Ipogonadismo nell’età adulta”. Giulianova (TE), 15-17 Settembre 2011.

·  Giornate Endocrinologiche Abruzzesi (GEA) 2010 “G. Flajani”. Presentazione di un caso clinico interattivo. L’Aquila, 8-9 Ottobre 2010.

·  Impotenza “che fortuna”! corso di aggiornamento organizzato dalla Sezione Puglia-Abruzzo della Società Italiana di Andrologia e Medicina della Sessualità (SIAMS). Presentazione di un caso clinico interattivo. Foggia, 5 luglio 2008.

·  Ipogonadismo, frequente disordine endocrino nell’anziano: quali implicazioni cliniche? corso di aggiornamento organizzato dalla Sezione Abruzzese della Società Italiana di Andrologia e Medicina della Sessualità (SIAMS). Presentazione di un caso clinico interattivo. L’Aquila, 17 Novembre 2007.

   

Relazioni su invito e comunicazioni orali in eventi internazionali:

 

·  22nd Congress of the European Society for Sexual Medicine (ESSM). Lecture (invited): ‘Male sexual health after spinal cord injury: impact on erection, sensation’. Prague, Czech Republic 23-25 January 2020.

·  10th European Congress of Andrology (ECA). Oral Presentation: ‘Antisperm-antibodies Prevalence and Relationship of Autoimunisation Degree with Semen Parameters And Post-coital Test Outcome. a Retrospective Analysis On Over 10,000 Men‘, Budapest, Hungary, 11-13 October 2018.

·  9th European Congress of Andrology (ECA). Lecture (invited): ‘Sexual function in men with spinal cord injury’, Rotterdam The Netherlands, 21-23 September 2016.

·  9th European Congress of Andrology (ECA). Oral Presentation: ‘2-Arachidonoylglycerol levels are increased in leukocytospermic ejaculates and correlate with semen concentration of macrophages and activated macrophages’, Rotterdam The Netherlands, 21-23 September 2016.

·  European Academy of Andrology Workshop on Management of Male Infertility. Unit of Andrology (Centre for clinical Andrology of the European Academy of Andrology), University of L’Aquila, S. Salvatore General Hospital, L’Aquila, Italy, 21-22 February 2013.

·  7th European Congress of Andrology (ECA). Oral Presentation: ‘Protective effect of probiotic lactobacilli against sperm damage exerted by soluble factors from Escherichia coli: focus on lipopolysaccharide’, Berlin, Germany, 28 November – 1 December 2012.

·  6th European Congress of Andrology (ECA). Oral Presentation: ‘Energetic metabolism and human sperm motiltiy: impact of CB1 receptor activation’, Athens, Greece, 29 September – 1 October 2010.

Curriculum english version

 

Personal information

Name

Arcangelo Barbonetti

 

E-mail

arcangelo.barbonetti@univaq.it

arcangelobarbonetti@virgilio.it

Nationality

Italian

Date of birth

31 May 1978

 

   

Work experience:

21/12/2018 - present

Assistant Professor/Lecturer in Endocrinology (SSD MED/13).

 

Department of Life, Health and Environment Sciences, University of L’Aquila.

Piazzale Salvatore Tommasi 1, 67100 Coppito (AQ), Italy.

 

01/11/2011 – 20/12/2018

Spinal Unit Physician (M.D.) and Consultant in Endocrinology/Andrology at the San Raffaele Rehabilitation Institute of Sulmona (Italy).

 

San Raffaele S.p.A.

Via di Val Cannuta 247, 00166 Rome, Italy.

 

 

10/12/2013 - 09/12/2014

Research Fellowship in Endocrinology/Andrology for the implementation of a research project entitled: ‘Identification of clinical, ultrasonographic and seminal prognostic factors on the effectiveness of varicocele repair in improving male fertility potential’ at the Medical Andrology Unit of the San Salvatore Hospital of L’Aquila.

Department of Life, Health and Environment Sciences, University of L’Aquila.

Piazzale Salvatore Tommasi 1, 67100 Coppito (AQ), Italy.

 

 

29/05/2012 - 29/05/2013

Research Fellowship in Endocrinology/Andrology for the implementation of a research project entitled: ‘Evaluation of the effects of internal spermatic vein scleroembolisation on scrotal colour Doppler ultrasound and semen parameters of patients with varicocele’ at the Medical Andrology Unit of the San Salvatore Hospital of L’Aquila.

ASL 1, Avezzano-Sulmona-L’Aquila, San Salvatore Hospital of L’Aquila.

Via Lorenzo Natali 1, 67100 Coppito (AQ), Italy.

 

 

2010 – 20/12/2018

Independent professional activity in the field of Endocrinology and Andrology

 

Teaching experience

Academic year

2019-2020

Teacher of ‘Andrology’ (SSD: MED/13) at the post-graduate school in Endocrinology, University of L’Aquila, Italy.

 

Academic year

2019-2020

Teacher of ‘Endocrinology (SSD: MED/13)’ and ‘Andrology (SSD: MED/13)’, degree course in Medicine, University of L’Aquila, Italy.

 

From the Academic year 2018-2019

Teacher of ‘Endocrinology (SSD: MED/13)’, degree course in Dentistry, University of L’Aquila, Italy.

 

Academic year

2018-2019

Teacher of ‘Endocrinology (SSD: MED/13)’, degree course in Dietetics, University of L’Aquila, Italy.

Academic year

 

2018-2019

Teacher of ‘Diabetology’ and ‘Lipid metabolism’ (SSD: MED/13) at the post-graduate school in Endocrinology, University of L’Aquila, Italy.

 

Academic year:

2016-2017

Teacher of ‘Principles of Endocrinology and Pathology of Sexual Behaviour’ (MED/13), degree course in Applied, Clinical and Health Psychology, University of L’Aquila, Italy.

 

From the Academic year 2016-2017

Teacher of ‘Andrology II’ (MED/04), degree course in Reproductive Biotechnologies, University of Teramo, Italy.

 

Academic year:

2011-2012 (22/3-12/6/2012)

Teacher of ‘Psycho-Endocrinological Changes’ (MED/13), degree course in Physical Education, University of L’Aquila, Italy.

 

From the Academic year: 2009-2010 to 2011-2012

Teacher of ‘Andrology II, Applied Technics’ (MED/13), degree course in Reproductive Biotechnologies, University of Teramo, Italy.

 

 

 

Education and training

2008-2012 – PhD Training in Internal Medicine and Applied Immunology with project in Andrology field; Thesis title: ‘Metabolismo energetico dello spermatozoo umano: dal modello biochimico del sistema endocannabinoide al modello clinico del paziente mieloleso’ (06/04/2012).

2003-2008 – Post Graduate Training (Residency) in Endocrinology (02/12/2008).

1997-2003 – Medical School (21/10/2003).

Title of qualification awarded

MD, PhD, Endocrinologist

 

University of L’Aquila

 

Level in national or international classification

ISCED8 (the highest educational degree in Italy)

 

05/04/2017

National Scientific Qualification for the functions of Second Tier Professor of Endocrinology (06/D2 - MED13) (https://asn16.cineca.it/pubblico/miur/esito-abilitato/06%252FD2/2/1).

 

29/09/2010

Qualification of Clinical Andrologist provided by the European Academy of Andrology (EAA) after training in the EAA center of L’Aquila, Italy (Medical Andrology Unit of the San Salvatore Hospital/University of L’Aquila).

 

Clinical and experimental research activities:

He is involved in research activities in the field of reproductive physiopathology since 2003 and during the last 10 years he dealt with research in the field of andrology and endocrinology of patients with spinal cord injury. The main fields of interest are the following: molecular mechanisms of the acquisition of sperm fertilizing ability, male immune infertility, the role of endocannabinoid system in the sperm functions and dysfunctions, energetic metabolism of human spermatozoa, pathophysiology of semen abnormalities in men with spinal cord injury and in patients with inflammation/infections of reproductive tract, sexual disorders and correlates of androgen deficiency in men with spinal cord injury, role of ultrasonography in the work-up of male infertility.

 

Awards:

·  Best Oral Presentation at the 12th National Congress of the Italian Society of Andrology and Sexual Medicine (SIAMS) in Rome, Italy, 1-3 December 2016, for the study: ‘In vitro exposure of human spermatozoa to bisphenol A induces a pro-oxidative and apoptotic mitochondrial dysfunction’.

·  Best Poster Presentation at the 7th European Congress of Andrology (ECA) in Berlin, Germany, 28 November – 1 December 2012, for the study: ‘Asthenozoospermia in spinal cord-injured men: a model for shedding light upon the contribution of glycolysis and mitochondrion in supporting sperm motility’.

·  Best Poster Presentation at the 10th National Congress of the Italian Society of Andrology and Sexual Medicine (SIAMS) in Lecce, Italy, 15-17 November 2012, for the study: ‘Protective effect of probiotic lactobacilli against sperm damage exerted by soluble factors from Escherichia coli: focus on lipopolysaccharide’.

·  Best clinical study at the National Conference of CNOPUS in Assisi, Italy, 12-14 November 2015 for the study: ‘Low testosterone leves are independently associated with non-alcoholic fatty liver disease in men with chronic spinal cord injury’.

 

Scientific Societies Affiliation:

·  Since 2006 Member of the Italian Society of Endocrinology (SIE). In 2015 elected Member of the Regional Coordination Committee for the Abruzzo with Secretary-Treasurer task.

·  Since 2009 Member of the Italian Society of Andrology and Sexual Medicine (SIAMS). From 2013 to 2016 Coordinator of the Newsletter Committee; From 2017 to 2018 coordinator of the Clinical-Scientific Update Commission; from 2015 to 2016 and since 2019 Member of the Scientific Commission; since 2017 regional Secretary for the Abruzzo. In charge of the Klinefelter ItaliaN Group (KING) project at the SIAMS Center of L’Aquila.

·  Since 2012 Member of the Italian Society of Spinal Cord (SIMS).

·  Since 2015 Affiliated member of the European Academy of Andrology (EAA).

 

 

Participation in national research projects:

·   PRIN 2004: ‘Effetto di modulatori farmacologici della motilità nemaspermica sulla capacità fecondante dello spermatozoo umano”- “Molecular mechanisms of sperm motility’.

·   PRIN 2005: ‘Meccanismi molecolari di regolazione della funzione spermatica e loro alterazioni’.

·   PRIN 2006: ‘Sistema endocannabinoide nell’acquisizione della capacità fecondante dello spermatozoo umano e nella sub-fertilità maschile’.

·   PRIN 2009: ‘Meccanismi di danno al DNA nemaspermico: aspetti molecolari e nuove prospettive cliniche’.

·   Clinical Study “Prevalenza della adiposità intRa-addOMInale e della SindromE metabolica nel DIAbete mellito di tipo 2 – PROMISE DIA”; Prot. n° RIMON_L_00019 (1/1/2006 - 30/6/2006).

 

PhD Academic Board Participation:

Since 2020, Arcangelo Barbonetti is part of the Academic Board of the PhD in Cellular and Molecular Biotechnologies (DOT13A8025) at the University of Teramo (Italy). Coordinator: Prof. Barbara Barboni.

 

Reviewer for the following journals:

The Journal of Clinical Endocrinology and Metabolism; Frontiers in Endocrinology; Andrology; The Journal of Sexual Medicine; Sexual Medicine; Journal of Clinical Medicine; Reproduction; Journal of Neurotrauma; Archives of Physical Medicine and Rehabilitation; The Journal of Spinal Cord Medicine; European Journal of Applied Physiology; Chemico-Biological Interactions; International Journal of Molecular Sciences; Nutrients; Cannabis and Cannabinoid Research; Health & Social Care in the Community; Therapeutic Advances in Reproductive Health; The Journal of Functional Foods; Environmental Pollution.

 

Editorial activities:

·  From 12/09/2016 to 01/01/2018 Member of the Editorial Board of ‘New Horizons in Clinical Case Reports’ (NHCCR, ISSN: 2352-9482), the official Elsevier publication of the European Society for Translational Medicine (EUSTM).

·  Guest Associate Editor of Frontiers in Endocrinology (IF 3.675) for the research topic: ‘Bisphenols and Male Reproductive Health’ (https://www.frontiersin.org/research-topics/11230/bisphenols-and-male-reproductive-health#overview).

·  Guest Associate Editor of Journal of Clinical Medicine (IF 5.688) for the special issue: ‘Erectile Dysfunction in Men with Chronic Diseases: from Pathophysiology to Clinical Management’ (https://www.mdpi.com/journal/jcm/special_issues/Erectile_Dysfunction).

 

 

 

International Peer-Reviewed Publications:

 

1.       Barbonetti A, Zugaro A, Sciarretta F, Santucci R, Necozione S, Ruvolo G, Francavilla S, Francavilla F. The inhibition of the human sperm phosphatidylinosytol 3-kinase by LY294002 does not interfere with sperm/oocyte interaction. Int J Androl 2006;29(4):468-74.

2.       Francavilla F, Barbonetti A, Necozione S, Santucci R, Cordeschi G, Macerola B, Francavilla S. Within-subject variation of seminal parameters in men with infertile marriages. Int J Androl 2007;30(3):174-81.

3.       Francavilla F, Santucci R, Barbonetti A, Francavilla S. Naturally-occurring antisperm antibodies in men: interference with fertility and clinical implications. An update. Front Biosci 2007;12:2890-911.

4.       Zugaro A, Pandolfi C, Barbonetti A, Vassallo MR, D'Angeli A, Necozione S, Colangeli MS, Francavilla S, Francavilla F. Retinol binding protein 4, low birth weight-related insulin resistance and hormonal contraception. Endocrine 2007;32(2):166-9.

5.       Barbonetti A, Vassallo MRC, Antonangelo C, Nuccetelli V, D’Angeli A, Pelliccione F, Giorgi M, Francavilla F, Francavilla S. RANTES (Regulated on Activation Normal T Expressed and Secreted chemokine) and human sperm fertilizing ability: effect on acrosome reaction and sperm/oocyte fusion. Mol Hum Reprod 2008;14(7):387-91.

6.       Pandolfi C, Zugaro A, Lattanzio F, Necozione S, Barbonetti A, Colangeli MS, Francavilla S, Francavilla F. Low birth weight and later development of insulin resistance and biochemical/clinical features of polycystic ovary syndrome. Metabolism 2008;57(7):999-1004.

7.       Barbonetti A, Vassallo MRC, Cinque B, Antonangelo C, Sciarretta F, Santucci R, D’Angeli A, Francavilla S, Francavilla F. Dynamics of the global tyrosine phosphorylation during capacitation and acquisition of the ability to fuse with oocytes in human spermatozoa. Biol Reprod 2008;79(4):649-56.

8.       Francavilla F, Sciarretta F, Sorgentone S, Necozione S, Santucci R, Barbonetti A, Francavilla S. Intrauterine insemination with or without mild ovarian stimulation in couples with male subfertility due to oligo/astheno- and/or teratozoospermia or antisperm antibodies: a prospective cross-over trial. Fertil Steril 2009;92(3):1009-11.

9.       Francavilla F, Battista N, Barbonetti A, Vassallo MR, Rapino C, Antonangelo C, Pasquariello N, Catanzaro G, Barboni B, Maccarrone M. Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability. Endocrinology 2009;150(10):4692-700.

10.    Barbonetti A, Vassallo MR, Pelliccione F, D'Angeli A, Santucci R, Muciaccia B, Stefanini M, Francavilla F, Francavilla S. Beta-chemokine receptor CCR5 in human spermatozoa and its relationship with seminal parameters. Hum Reprod 2009;24(12):2979-87.

11.    Barbonetti A, Vassallo MRC, Cordeschi G, Venetis D, Carboni A, Sperandio A, Felzani G, Francavilla S, Francavilla F. Protein tyrosine phosphorylation of the human sperm head during capacitation: immunolocalization and relationship with acquisition of sperm-fertilizing ability. Asian J Androl 2010;12(6):853-61.

12.    Barbonetti A, Vassallo MRC, Fortunato D, Francavilla S, Maccarrone M, Francavilla F. Energetic metabolism and human sperm motility: impact of CB1 receptor activation. Endocrinology 2010; 151(12):5882-92.

13.    Barbonetti A, Cinque B, Vassallo MRC, Mineo S, Francavilla S, Cifone MG, Francavilla F. Effect of vaginal probiotic lactobacilli on in vitro induced sperm lipid peroxidation and its impact on sperm motility and viability. Fertil Steril 2011;95(8):2485-8.

14.    Barbonetti A, Cavallo F, Felzani G, Francavilla S, Francavilla F. Erectile dysfunction is the main determinant of psychological distress in men with spinal cord injury. J Sex Med 2012;9(3):830-6.

15.    Pelliccione F, D’Angeli A, Filipponi S, Falone S, Necozione S, Barbonetti A, Francavilla F, Francavilla S. Serum from patients with erectile dysfunction inhibits circulating angiogenic cells from healthy men: relationship with cardiovascular risk, endothelial damage and circulating angiogenic modulators. Int J Androl 2012;35(5):645-52.

16.    Pezzella A, Barbonetti A, Micillo A, D’Andrea S, Necozione S, Gandini L, Lenzi A, Francavilla F, Francavilla S. Ultrasonoghraphic determination of caput epididymidis diameter is strongly predictive of obstruction in the genital tract in azoospermic men with normal serum FSH. Andrology 2013;1(1):133-8.

17.    Barbonetti A, Vassallo MRC, Di Rosa A, Leombruni Y, Felzani G, Gandini L, Lenzi A, Necozione S, Francavilla S, Francavilla F. Involvement of mitochondrial dysfunction in the adverse effect exerted by seminal plasma from men with spinal cord injury on sperm motility. Andrology 2013; 1(3):456-63.

18.    Barbonetti A, Vassallo MRC, Cinque B, Filipponi S, Mastromarino P, Cifone MG, Francavilla S, Francavilla F.  Soluble products of Escherichia coli induce mitochondrial dysfunction-related sperm membrane lipid peroxidation which is prevented by lactobacilli. PLoS ONE 2013;8(12):e83136.

19.    Pelliccione F, D’Angeli A, D’Andrea S, Barbonetti A, Pezzella A, Necozione S, Falone S, Amicarelli F, Francavilla F, Francavilla S. Tadalafil treatment had a modest effect on endothelial cell damage and repair ability markers in men with erectile dysfunction and vascular risk. Asian J Androl 2014;16(2):290-4.

20.    Barbonetti A, Vassallo MR, Costanzo M, Battista N, Maccarrone M, Francavilla S, Francavilla F. Involvement of cannabinoid receptor-1 activation in mitochondrial depolarizing effect of lipopolysaccharide in human spermatozoa. Andrology 2014;2(4):502-9.

21.    Pezzella A, Barbonetti A, D'Andrea S, Necozione S, Micillo A, Di Gregorio A, Francavilla F, Francavilla S. Ultrasonographic caput epididymis diameter is reduced in non-obstructive azoospermia compared with normozoospermia but is not predictive for successful sperm retrieval after TESE. Hum Reprod 2014;29(7):1368-74.

22.    Barbonetti A, Vassallo MRC, Pacca F, Cavallo F, Costanzo M, Felzani G, Francavilla S, Francavilla F. Correlates of low testosterone in men with chronic spinal cord injury. Andrology 2014;2(5):721-8.

23.    Mastromarino P, Hemalatha R, Barbonetti A, Cinque B, Cifone MG, Tammaro F, Francavilla F. Biological control of vaginosis to improve reproductive health. Indian J Med Res 2014;140 Suppl:S91-7.

24.    Francavilla F, Barbonetti A. Letter to the Editor: Comment on Gaspar AP, Brandão CM, Lazaretti-Castro M. Bone mass and hormone analysis in spinal cord injury patients: evidences for a gonadal axis disruption. J Clin Endocrinol Metab 2015;100(2):L20.

25.    D'Andrea S, Giordano AV, Carducci S, Sacchetti L, Necozione S, Costanzo M, De Gregorio A, Micillo A, Francavilla F, Francavilla S, Barbonetti A. Embolization of left spermatic vein in non-obstructive azoospermic men with varicocele: role of FSH to predict the appearance of ejaculated spermatozoa after treatment. J Endocrinol Invest 2015;38(7):785-90.

26.    Barbonetti A, Vassallo MR, Felzani G, Francavilla S, Francavilla F. Association between 25(OH)-vitamin D and testosterone levels: evidence from men with chronic spinal cord injury. J Spinal Cord Med 2016;39(3):246-52.

27.    Barbonetti A, Caterina Vassallo MR, Cotugno M, Felzani G, Francavilla S, Francavilla F. Low testosterone and non-alcoholic fatty liver disease: Evidence for their independent association in men with chronic spinal cord injury. J Spinal Cord Med 2016;39(4):443-9.

28.    Barbonetti A, Sperandio A, Micillo A, D'Andrea S, Pacca F, Felzani G, Francavilla S, Francavilla F. Independent Association of Vitamin D With Physical Function in People With Chronic Spinal Cord Injury. Arch Phys Med Rehabil 2016;97(5):726-32. 

29.    Micillo A, Vassallo MR, Cordeschi G, D'Andrea S, Necozione S, Francavilla F, Francavilla S, Barbonetti A. Semen leukocytes and oxidative-dependent DNA damage of spermatozoa in male partners of subfertile couples with no symptoms of genital tract infection. Andrology 2016;4(5):808-15.

30.    D’Andrea S, Micillo A, Francavilla F, Di Emidio G, Tatone C, Francavilla S, Barbonetti A. Serum from patients with erectile dysfunction and vascular risk factors triggered an oxidative stress-dependent mitochondrial apoptotic pathway in ex vivo expanded circulating angiogenic cells of healthy men. J Sex Med 2016;13(7):1063-70.

31.    Barbonetti A, Castellini C, Di Giammarco N, Santilli G, Francavilla S, Francavilla F. In vitro exposure of human spermatozoa to bisphenol A induces pro-oxidative/apoptotic mitochondrial dysfunction. Reprod Toxicol 2016;66:61-7. 

32.    Barbonetti A, Bisogno T, Battista N, Piscitelli F, Micillo A, Francavilla S, Maccarrone M, Francavilla F. 2-arachidonoylglycerol levels are increased in leukocytospermia and correlate with seminal macrophages. Andrology 2017;5(1):87-94.

33.    Barbonetti A, Cavallo F, D'Andrea S, Muselli M, Felzani G, Francavilla S, Francavilla F. Lower Vitamin D Levels Are Associated With Depression in People With Chronic Spinal Cord Injury. Arch Phys Med Rehabil 2017;98(5):940-6.

34.    D'Andrea S, Micillo A, Barbonetti A, Giordano AV, Carducci S, Mancini A, Necozione S, Francavilla F, Francavilla S. Determination of spermatic vein reflux after varicocele repair helps to define the efficacy of treatment in improving sperm parameters of subfertile men. J Endocrinol Invest 2017;40(10):1145-53.

35.    Barbonetti A, D'Andrea S, Martorella A, Felzani G, Francavilla S, Francavilla F. Low vitamin D levels are independent predictors of 1-year worsening in physical function in people with chronic spinal cord injury: a longitudinal study. Spinal Cord 2018;56(5):494-501.

36.    Barbonetti A, Calogero AE, Balercia G, Garolla A, Krausz C, La Vignera S, Lombardo F, Jannini EA, Maggi M, Lenzi A, Foresta C, Ferlin A. The use of follicle stimulating hormone (FSH) for the treatment of the infertile man: position statement from the Italian Society of Andrology and Sexual Medicine (SIAMS). J Endocrinol Invest 2018;41(9):1107-1122.

37.    Tatone C, Di Emidio G, Barbonetti A, Carta G, Luciano AM, Falone S, Amicarelli F. Sirtuins in gamete biology and reproductive physiology: emerging roles and therapeutic potential in female and male infertility. Hum Reprod Update 2018;24(3):267-89.

38.    Barbonetti A, D'Andrea S, Samavat J, Martorella A, Felzani G, Francavilla S, Luconi M, Francavilla F. Can the positive association of osteocalcin with testosterone be unmasked when the preeminent hypothalamic-pituitary regulation of testosterone production is impaired? The model of spinal cord injury. J Endocrinol Invest 2019;42(2):167-173.

39. Vezzani S, Giannetta E, Altieri B, Barbonetti A, Bellastella G, Certo R, Cignarelli A, Cinti F, D'Andrea S, Di Dalmazi G, Frara S, Garelli S, Giuffrida G, Maiorino MI, Mele C, Mezza T, Pani MG, Samà MT, Satta C, Santi D. An italian survey of compliance with major guidelines for L-thyroxine of primary hypothyroidism. Endocr Pract 2018;24(5):419-28.

40. Barbonetti A, D'Andrea S, Martorella A, Felzani G, Francavilla S, Francavilla F. Risk of prostate cancer in men with spinal cord injury: A systematic review and meta-analysis. Asian J Androl 2018;20(6):555-560.

41. D'Andrea S, Barbonetti A, Castellini C, Martorella A, Minaldi E, Viktor Giordano A, Carducci S, Necozione S, Francavilla F, Francavilla S. Reproductive hormones and sperm parameters after varicocele repair: An observational study. Andrologia. 2018;50(10):e13118.

42.    D'Andrea S, Barbonetti A, Martorella A, Necozione S, Francavilla F, Francavilla S. Effect of prolonged treatment with phosphodiesterase-5-inhibitors on endothelial dysfunction in vascular diseases and vascular risk conditions: A systematic review analysis and meta-analysis of randomized double-blind placebo-controlled trials. Int J Clin Pract 2019;73(2):e13296.

43.    Guadagni V, Sarà M, Conson M, Carolei A, Sacco S, Vadini S, Pistarini C, Barbonetti A, Iaria G, Pistoia F. Cognitive and Emotional Empathy in Individuals with Spinal Cord Injury. Behav Neurol 2019;2019:1312934. 44.    Barbonetti A, D'Andrea S, Cavallo F, Martorella A, Francavilla S, Francavilla F. Erectile Dysfunction and Premature Ejaculation in Homosexual and Heterosexual Men: A Systematic Review and Meta-Analysis of Comparative Studies. J Sex Med 2019;16(5):624-632. 

45.    Barbonetti A, Castellini C, D'Andrea S, Cordeschi G, Santucci R, Francavilla S, Francavilla F. Prevalence of anti-sperm antibodies and relationship of degree of sperm auto-immunization to semen parameters and post-coital test outcome: a retrospective analysis of over 10 000 men. Hum Reprod 2019;34(5):834-841.

46.    Barbonetti A, Martorella A, Minaldi E, D'Andrea S, Bardhi D, Castellini C,Francavilla F, Francavilla S. Testicular Cancer in Infertile Men With and Without Testicular Microlithiasis: A Systematic Review and Meta-Analysis of Case-Control Studies. Front Endocrinol (Lausanne) 2019;10:164. doi:10.3389/fendo.2019.00164. eCollection 2019.

47.    D'Andrea S, Barbonetti A, Castellini C, Nolletti L, Martorella A, Minaldi E,Giordano AV, Carducci S, Necozione S, Francavilla F, Francavilla S. Left spermatic vein reflux after varicocele repair predicts pregnancies and live births in subfertile couples. J Endocrinol Invest 2019;42(10):1215-1221.

48.    Castellini C, D’Andrea S, Martorella A, Minaldi E, Necozione S, Francavilla F, Francavilla S, Barbonetti A. Relationship between leukocytospermia, reproductive potential after assisted reproductive technology, and sperm parameters: a systematic review and meta-analysis of case-control studies. Andrology 2020;;8(1):125-135.

49.    Minaldi E, D'Andrea S, Castellini C, Martorella A, Francavilla F, Francavilla S, Barbonetti A. Thyroid autoimmunity and risk of post-partum depression: a systematic review and meta-analysis of longitudinal studies. J Endocrinol Invest 2020;43(3):271-277.

50.    D'Andrea S, Pallotti F, Senofonte G, Castellini C, Paoli D, Lombardo F, Lenzi A, Francavilla S, Francavilla F, Barbonetti A. Polymorphic Cytosine-Adenine-Guanine Repeat Length of Androgen Receptor Gene and Gender Incongruence in Trans Women: A Systematic Review and Meta-Analysis of Case-Control Studies. J Sex Med 2020;17(3):543-550.

51.    D'Andrea S, Castellini C, Paladino V, Totaro M, Felzani G, Francavilla S, Francavilla F, Barbonetti A. Metabolic syndrome is the key determinant of impaired vaginal lubrication in women with chronic spinal cord injury. J Endocrinol Invest 2020 Jan 25. doi: 10.1007/s40618-020-01185-w.

52.    Barbonetti A, D'Andrea S, Francavilla S. Testosterone replacement therapy. Andrology 2020 Feb 18. doi: 10.1111/andr.12774.

53.    D'Andrea S, Minaldi E, Castellini C, Cavallo F, Felzani G, Francavilla S, Francavilla F, Barbonetti A. Independent Association of Erectile Dysfunction and Low Testosterone Levels With Life Dissatisfaction in Men With Chronic Spinal Cord Injury. J Sex Med 2020 Feb 20. doi: 10.1016/j.jsxm.2020.01.018.

54.    D'Andrea S, Castellini C, Minaldi E, Totaro M, Felzani G, Francavilla S, Francavilla F, Barbonetti A. Testosterone, level of the lesion and age are independently associated with prostate volume in men with chronic spinal cord injury. J Endocrinol Invest 2020 Apr 4. doi: 10.1007/s40618-020-01243-3.

55.    D'Andrea S, Spaggiari G, Barbonetti A, Santi D. Endogenous transient doping: physical exercise acutely increases testosterone levels-results from a meta-analysis. J Endocrinol Invest 2020 Apr 15. doi: 10.1007/s40618-020-01251-3.

56.    Lotti F, Frizza F, Balercia G, Barbonetti A, Behre HM, Calogero AE, Cremers JF, Francavilla F, Isidori AM, Kliesch S, La Vignera S, Lenzi A, Marcou M, Pilatz A, Poolamets O, Punab M, Peraza Godoy MF, Rajmil O, Salvio G, Shaeer O, Weidner W, Maseroli E, Cipriani S, Baldi E, Degl'Innocenti S, Danza G, Caldini AL, Terreni A, Boni L, Krausz C, Maggi M. The European Academy of Andrology (EAA) ultrasound study on healthy, fertile men: clinical, seminal and biochemical characteristics. Andrology 2020 Apr 30. doi: 10.1111/andr.12808.

57.    Barbonetti A, Castellini C, D'Andrea S, Minaldi E, Totaro M, Francavilla S, Francavilla F. Relationship between natural and intrauterine insemination-assisted live births and the degree of sperm autoimmunisation. Hum Reprod 2020 May 2. pii: deaa070. doi: 10.1093/humrep/deaa070.            

   

Other publications: 

1.        Santucci R, Barbonetti A, Necozione S, Francavilla F. Valutazione dei trattamenti dell’ipofertilità idiopatica maschile: quale end-point? Foresta C. (ed). La riproduzione umana e le influenze ambientali, Libraria Editrice Università di Padova, 2006: pp. 61-68.

2.        Barbonetti A, Sciarretta F, Francavilla F. Fisiopatologia iatrogena. Lenzi A., Jannini E.A., Maggi M. (eds). Trattato di  sessuologia medica, Elsevier Masson, 2007; Cap. 59 (impotenza): pp. 291-298.

3.        Francavilla F, Barbonetti A. Male Autoimmune Infertility. Krause W.K.H. and Naz R.K. (eds.), Immune Infertility, ©Springer Verlag Berlin Heidelberg, 2009: pp. 145-153.

4.        Francavilla F, Barbonetti A. Infertilità. Attanasio R., Castello R., Dorizzi R., Ferone D., Giagulli V., Lenzi A., Martinelli M., Toscano V., Valentini F., Valota M. (eds.), Diagnostica in Endocrinologia Clinica – Manuale per valutazione e inquadramento delle patologie gonadiche, Scripta s.c. press., Verona, 2009: pp. 143-155; 311-313.

5.        Barbonetti A, Cordeschi G, Francavilla F. Indicazione e metodi di crioconservazione degli spermatozoi. Foresta C., Ferlin A., Lenzi A., Garolla A. (eds), La medicina della riproduzione dalla sperimentazione alla clinica, CLEUPS S.c. Libraria Editrice Università di Padova, 2011: pp. 315-319.

6.        Barbonetti A, Francavilla F. Biochimica del liquido seminale. Lenzi A., Foresta C., Jannini E.A., Maggi M. (eds), Guida allo studio dell’andrologia, Società Editrice Universo, 2012; Cap. 9: pp. 65-70.

7.        Francavilla F, Barbonetti A. Infertility: Immunological Aspects. 2012; In: eLS. John Wiley & Sons, Ltd: Chichester. DOI: 10.1002/978047001 5902.a0000967. pub2. www.els.net.

8.        Francavilla F, Barbonetti A. Male Autoimmune Infertility. In: WKH Krause & RK Naz (eds.): Immune infertility: Impact of Immune Reactions on Human Fertility. Second Edition. ©Springer Verlag Berlin Heidelberg, 2017: pp. 187-196.

9.        Barbonetti A, Sciarretta F, Francavilla F. Fisiopatologia iatrogena. EA Jannini, A Lenzi, M Maggi (eds). Sessuologia medica. Trattato di psicosessuologia, medicina della sessualità e salute della coppia, Seconda edizione. Edra S.p.A., Milano, 2017; Cap. 61 (Patologia dell’erezione): pp. 308-316.

10.     Ciocca G, Zauri S, Limoncin E, Mollaioli D, Niolu C, Bianciardi E, Siracusano A, D'Andrea S, Barbonetti A, Jannini EA. Psicoendocrinologia e psicopatologia delle transizioni di genere. Noos 2018;24(3):135-141. DOI: 10.1722/3152.31323.

11.     Francavilla F, Barbonetti A, D’Andrea S, Francavilla S. Diagnostica e approccio terapeutico della induratio penis plastica. L'Endocrinologo 2019;20:33. https://doi.org/10.1007/s40619-019-00518-z. 

 

Invitations to National Events:

 ·  KING 2.0 Conference: “La sindrome di Klinefelter: la forma classica e le sue varianti”. Discussant of the session: “Complicanze cliniche II”, Naples, 25-26 October 2019.

·  34rd Conference of Reproductive Medicine. Denatalità e ipofertilità: quale ruolo per l’ambiente. Discussant of the session: “Terapia delle Insufficienze gonadiche”, Abano (PD), Italy, 01-02 March 2019.

·  Conference: ‘Identità sessuali: il senso di Sé oltre il pregiudizio e la sofferenza‘. Lecture: “Neuroendocrinobiologia dell’identità transessuale”, L’Aquila, Italy, 9 November 2018.

·  XIII National Congress of the Italian Society of Andrology and Sexual Medicine (SIAMS), Lecture: ‘Il trattamento con FSH nel maschio con infertilità idiopatica’, Catania, Italy, 25-27 October 2018.

·  Conference: ‘Personalizzazione dei percorsi diagnostici e terapeutici: una visione d’insieme’, lecture: ‘Infertilità immunologica maschile e trattamento farmacologico’, Sora (FR), Italy, 26 May 2018. 

·  Conference: ‘IIEM (Incontri Italiani di Endocrinologia e Metabolismo) of the Italian Society of Endocrinology (SIE)’, lecture: ‘Nuove linee guida nella diagnosi di ipogonadismo: revisione critica’, Bari, Italy, 10-11 May 2018.

·  33rd Conference of Reproductive Medicine, lecture: ‘Ipogonadismo ipogonadotropo e terapia con FSH nel maschio’. Abano (PD), Italy, 23-24 February 2018.

·  I Androyoung National Congress, Italian Society of Andrology and Sexual Medicine (SIAMS). Chairman for the lecture: “La terapia con FSH nell’infertilità maschile”. Rimini, Italy, 17-18 November 2017. 

·  Scientific Manager of the course entitled: ‘La sessualità nell’uomo fragile’ with the lecture: ‘disfunzioni sessuali nell’uomo fragile’. Sulmona (AQ), Italy, 21 October 2017.

·  2nd National Conference of Sulmona, lecture: ‘Bisfenoli e fertilità maschile’. Sulmona (AQ), Italy, 10-11 April 2015.

·  Conference: ‘Endo Games 2015’, presentation of an interactive case report on adulthood onset hypogonadism. Chieti, Italy, 19-21 February 2015.

·  11th National Congress of the Italian Society of Andrology and Sexual Medicine (SIAMS), lecture: ‘Sessualità e ipogonadismo nell’uomo fragile: paziente con lesione midollare’. Cagliari, Italy, 13-15 November 2014.

·  30th National Congress of ANASMES (Associazione Nazionale Specialisti in Medicina dello Sport), lecture: ‘Performance e carenza androgenica: il modello del paziente mieloleso’. Chieti, Italy, 29-31 May – 1 June 2014.

·  San Raffaele conference entitled: ‘Il dolore nel paziente con lesione del midollo spinale’, lecture: ‘Terapia farmacologica’. Sulmona (AQ), Italy, 30 December 2013.

·  Giornate Endocrinologiche Abruzzesi (GEA) 2013, lecture: ‘Terapia sostitutiva nel maschio’. Teramo, Italy, 17-18 May 2013.

·  San Raffaele conference entitled: ‘Problematiche sessuali e riproduttive nella disabilità neuromotoria’, lecture: ‘Distress psicologico nei mielolesi con o senza disfunzione erettile: dati dal San Raffaele Sulmona’.  Sulmona (AQ), Italy, 14 November 2012.

·  San Raffaele conference entitled: ‘La disreflessia autonomica nel paziente con lesione midollare’, lecture on the Reproductive System. Sulmona (AQ), Italy, 26 September 2012.

·  Giornate Endocrinologiche Abruzzesi (GEA) 2012, lecture: ‘Ipogonadismo nel paziente internistico: condizione da trattare?’. Lanciano (CH), Italy 8-9 June 2012.

·  Conference entitled: ‘La fertilità tra biologia e cultura’, lecture: ‘Possibilità terapeutiche per l’uomo infertile’. Teramo, Italy, 18 May 2012.

·  Conference entitled: ‘Problematiche endocrinologiche dal concepimento all’età adulta’, lecture: ‘Ipogonadismo nell’età adulta’. Giulianova (TE), Italy, 15-17 September 2011.

·  Giornate Endocrinologiche Abruzzesi (GEA) 2010, presentation the interactive case report: ‘Osteoporosi in un uomo adulto’. L’Aquila, Italy, 8-9 October 2010.

·  Conference of the Puglia-Abruzzo’s section of the Italian Society of Andrology and Sexual Medicine (SIAMS) entitled ‘Impotenza “che fortuna”!’, presentation of an interactive case report. Foggia, Italy, 5 July 2008.

·  Conference of the Abruzzo’s section of the Italian Society of Andrology and Sexual Medicine (SIAMS) entitled: ‘Ipogonadismo, frequente disordine endocrino nell’anziano: quali implicazioni cliniche?’, presentation of an interactive case report. L’Aquila, Italy, 17 November 2007.

 

Invited Lectures and Oral Presentations to International Events:

·  22nd Congress of the European Society for Sexual Medicine (ESSM). Lecture (invited): ‘Male sexual health after spinal cord injury: impact on erection, sensation’. Prague, Czech Republic 23-25 January 2020.

·  10th European Congress of Andrology (ECA). Oral Presentation: ‘Antisperm-antibodies Prevalence and Relationship of Autoimunisation Degree with Semen Parameters And Post-coital Test Outcome. a Retrospective Analysis On Over 10,000 Men‘, Budapest, Hungary, 11-13 October 2018.

·  9th European Congress of Andrology (ECA). Lecture (invited): ‘Sexual function in men with spinal cord injury’, Rotterdam The Netherlands, 21-23 September 2016.

·  9th European Congress of Andrology (ECA). Oral Presentation: ‘2-Arachidonoylglycerol levels are increased in leukocytospermic ejaculates and correlate with semen concentration of macrophages and activated macrophages’, Rotterdam The Netherlands, 21-23 September 2016.

·  European Academy of Andrology Workshop on Management of Male Infertility. Unit of Andrology (Centre for clinical Andrology of the European Academy of Andrology), University of L’Aquila, S. Salvatore General Hospital, L’Aquila, Italy, 21-22 February, 2013.

·  7th European Congress of Andrology (ECA). Oral Presentation: ‘Protective effect of probiotic lactobacilli against sperm damage exerted by soluble factors from Escherichia coli: focus on lipopolysaccharide’, Berlin, Germany, 28 November – 1 December 2012.

·  6th European Congress of Andrology (ECA). Oral Presentation: ‘Energetic metabolism and human sperm motiltiy: impact of CB1 receptor activation’, Athens, Greece, 29 September – 1 October 2010.

Pubblicazioni

 

Articoli in extenso in periodici internazionali indicizzati su PubMed:

 

1: Barbonetti A, Castellini C, D'Andrea S, Minaldi E, Totaro M, Francavilla S, Francavilla F. Relationship between natural and intrauterine insemination-assisted live births and the degree of sperm autoimmunisation. Hum Reprod. 2020 May 2. pii: deaa070. doi: 10.1093/humrep/deaa070. [Epub ahead of print] PubMed PMID: 32358600.

 

2: Lotti F, Frizza F, Balercia G, Barbonetti A, Behre HM, Calogero AE, Cremers JF, Francavilla F, Isidori AM, Kliesch S, La Vignera S, Lenzi A, Marcou M, Pilatz A, Poolamets O, Punab M, Peraza Godoy MF, Rajmil O, Salvio G, Shaeer O, Weidner W, Maseroli E, Cipriani S, Baldi E, Degl'Innocenti S, Danza G, Caldini AL, Terreni A, Boni L, Krausz C, Maggi M. The European Academy of Andrology (EAA) ultrasound study on healthy, fertile men: clinical, seminal and biochemical characteristics. Andrology. 2020 Apr 30. doi: 10.1111/andr.12808. [Epub ahead of print] PubMed PMID: 32353207.

 

3: D'Andrea S, Spaggiari G, Barbonetti A, Santi D. Endogenous transient doping: physical exercise acutely increases testosterone levels-results from a meta-analysis. J Endocrinol Invest. 2020 Apr 15. doi: 10.1007/s40618-020-01251-3. [Epub ahead of print] Review. PubMed PMID: 32297287.

 

4: D'Andrea S, Castellini C, Minaldi E, Totaro M, Felzani G, Francavilla S, Francavilla F, Barbonetti A. Testosterone, level of the lesion and age are independently associated with prostate volume in men with chronic spinal cord injury. J Endocrinol Invest. 2020 Apr 4. doi: 10.1007/s40618-020-01243-3. [Epub ahead of print] PubMed PMID: 32248510.

 

5: D'Andrea S, Minaldi E, Castellini C, Cavallo F, Felzani G, Francavilla S, Francavilla F, Barbonetti A. Independent Association of Erectile Dysfunction and Low Testosterone Levels With Life Dissatisfaction in Men With Chronic Spinal Cord Injury. J Sex Med. 2020 May;17(5):911-918. doi: 10.1016/j.jsxm.2020.01.018. Epub 2020 Feb 20. PubMed PMID: 32089485.

 

6: Barbonetti A, D'Andrea S, Francavilla S. Testosterone replacement therapy. Andrology. 2020 Feb 18. doi: 10.1111/andr.12774. [Epub ahead of print] Review. PubMed PMID: 32068334.

 

7: D'Andrea S, Castellini C, Paladino V, Totaro M, Felzani G, Francavilla S, Francavilla F, Barbonetti A. Metabolic syndrome is the key determinant of impaired vaginal lubrication in women with chronic spinal cord injury. J Endocrinol Invest. 2020 Jan 25. doi: 10.1007/s40618-020-01185-w. [Epub ahead of print] PubMed PMID: 31983040.

 

8: D'Andrea S, Pallotti F, Senofonte G, Castellini C, Paoli D, Lombardo F, Lenzi A, Francavilla S, Francavilla F, Barbonetti A. Polymorphic Cytosine-Adenine-Guanine Repeat Length of Androgen Receptor Gene and Gender Incongruence in Trans Women: A Systematic Review and Meta-Analysis of Case-Control Studies. J Sex Med. 2020 Mar;17(3):543-550. doi: 10.1016/j.jsxm.2019.12.010. Epub 2020 Jan 8. PubMed PMID: 31926901.

 

9: Minaldi E, D'Andrea S, Castellini C, Martorella A, Francavilla F, Francavilla S, Barbonetti A. Thyroid autoimmunity and risk of post-partum depression: a systematic review and meta-analysis of longitudinal studies. J Endocrinol Invest. 2020 Mar;43(3):271-277. doi: 10.1007/s40618-019-01120-8. Epub 2019 Sep 24. Review. PubMed PMID: 31552596.

 

10: Castellini C, D'Andrea S, Martorella A, Minaldi E, Necozione S, Francavilla F, Francavilla S, Barbonetti A. Relationship between leukocytospermia, reproductive potential after assisted reproductive technology, and sperm parameters: a systematic review and meta-analysis of case-control studies. Andrology. 2020 Jan;8(1):125-135. doi: 10.1111/andr.12662. Epub 2019 Jun 28. PubMed PMID: 31250986.

 

11: D'Andrea S, Barbonetti A, Castellini C, Nolletti L, Martorella A, Minaldi E, Giordano AV, Carducci S, Necozione S, Francavilla F, Francavilla S. Left spermatic vein reflux after varicocele repair predicts pregnancies and live births in subfertile couples. J Endocrinol Invest. 2019 Oct;42(10):1215-1221. doi: 10.1007/s40618-019-01042-5. Epub 2019 Apr 6. PubMed PMID: 30955179.

 

12: Barbonetti A, Martorella A, Minaldi E, D'Andrea S, Bardhi D, Castellini C, Francavilla F, Francavilla S. Testicular Cancer in Infertile Men With and Without Testicular Microlithiasis: A Systematic Review and Meta-Analysis of Case-Control Studies. Front Endocrinol (Lausanne). 2019 Mar 21;10:164. doi: 10.3389/fendo.2019.00164. eCollection 2019. PubMed PMID: 30949131; PubMed Central PMCID: PMC6437042.

 

13: Barbonetti A, Castellini C, D'Andrea S, Cordeschi G, Santucci R, Francavilla S, Francavilla F. Prevalence of anti-sperm antibodies and relationship of degree of sperm auto-immunization to semen parameters and post-coital test outcome: a retrospective analysis of over 10 000 men. Hum Reprod. 2019 May 1;34(5):834-841. doi: 10.1093/humrep/dez030. PubMed PMID: 30927424.

 

14: Barbonetti A, D'Andrea S, Cavallo F, Martorella A, Francavilla S, Francavilla F. Erectile Dysfunction and Premature Ejaculation in Homosexual and Heterosexual Men: A Systematic Review and Meta-Analysis of Comparative Studies. J Sex Med. 2019 May;16(5):624-632. doi: 10.1016/j.jsxm.2019.02.014. Epub 2019 Mar 26. Review. PubMed PMID: 30926517.

 

15: Guadagni V, Sarà M, Conson M, Carolei A, Sacco S, Vadini S, Pistarini C, Barbonetti A, Iaria G, Pistoia F. Cognitive and Emotional Empathy in Individuals with Spinal Cord Injury. Behav Neurol. 2019 Feb 10;2019:1312934. doi: 10.1155/2019/1312934. eCollection 2019. PubMed PMID: 30881519; PubMed Central PMCID: PMC6387693.

 

16: D'Andrea S, Barbonetti A, Martorella A, Necozione S, Francavilla F, Francavilla S. Effect of prolonged treatment with phosphodiesterase-5-inhibitors on endothelial dysfunction in vascular diseases and vascular risk conditions: A systematic review analysis and meta-analysis of randomized double-blind placebo-controlled trials. Int J Clin Pract. 2019 Feb;73(2):e13296. doi: 10.1111/ijcp.13296. Epub 2018 Dec 18. PubMed PMID: 30471172.

 

17: D'Andrea S, Barbonetti A, Castellini C, Martorella A, Minaldi E, Viktor Giordano A, Carducci S, Necozione S, Francavilla F, Francavilla S. Reproductive hormones and sperm parameters after varicocele repair: An observational study. Andrologia. 2018 Dec;50(10):e13118. doi: 10.1111/and.13118. Epub 2018 Jul 25. PubMed PMID: 30043529.

 

18: Barbonetti A, D'Andrea S, Martorella A, Felzani G, Francavilla S, Francavilla F. Risk of prostate cancer in men with spinal cord injury: A systematic review and meta-analysis. Asian J Androl. 2018 Nov-Dec;20(6):555-560. doi: 10.4103/aja.aja_31_18. PubMed PMID: 29956686; PubMed Central PMCID: PMC6219305.

 

19: Vezzani S, Giannetta E, Altieri B, Barbonetti A, Bellastella G, Certo R, Cignarelli A, Cinti F, D'Andrea S, Di Dalmazi G, Frara S, Garelli S, Giuffrida G, Maiorino MI, Mele C, Mezza T, Pani MG, Samà MT, Satta C, Santi D. AN ITALIAN SURVEY OF COMPLIANCE WITH MAJOR GUIDELINES FOR L-THYROXINE OF PRIMARY HYPOTHYROIDISM. Endocr Pract. 2018 May;24(5):419-428. doi: 10.4158/EP-2017-0159. PubMed PMID: 29847168.

 

20: Barbonetti A, D'Andrea S, Samavat J, Martorella A, Felzani G, Francavilla S, Luconi M, Francavilla F. Can the positive association of osteocalcin with testosterone be unmasked when the preeminent hypothalamic-pituitary regulation of testosterone production is impaired? The model of spinal cord injury. J Endocrinol Invest. 2019 Feb;42(2):167-173. doi: 10.1007/s40618-018-0897-x. Epub 2018 May 4. PubMed PMID: 29729005.

 

21: Tatone C, Di Emidio G, Barbonetti A, Carta G, Luciano AM, Falone S, Amicarelli F. Sirtuins in gamete biology and reproductive physiology: emerging roles and therapeutic potential in female and male infertility. Hum Reprod Update. 2018 May 1;24(3):267-289. doi: 10.1093/humupd/dmy003. Review. PubMed PMID: 29447380.

 

22: Barbonetti A, Calogero AE, Balercia G, Garolla A, Krausz C, La Vignera S, Lombardo F, Jannini EA, Maggi M, Lenzi A, Foresta C, Ferlin A. The use of follicle stimulating hormone (FSH) for the treatment of the infertile man: position statement from the Italian Society of Andrology and Sexual Medicine (SIAMS). J Endocrinol Invest. 2018 Sep;41(9):1107-1122. doi: 10.1007/s40618-018-0843-y. Epub 2018 Feb 1. PubMed PMID: 29392544.

 

23: Barbonetti A, D'Andrea S, Martorella A, Felzani G, Francavilla S, Francavilla F. Low vitamin D levels are independent predictors of 1-year worsening in physical function in people with chronic spinal cord injury: a longitudinal study. Spinal Cord. 2018 May;56(5):494-501. doi: 10.1038/s41393-017-0058-7. Epub 2018 Jan 16. PubMed PMID: 29335474.

 

24: D'Andrea S, Micillo A, Barbonetti A, Giordano AV, Carducci S, Mancini A, Necozione S, Francavilla F, Francavilla S. Determination of spermatic vein reflux after varicocele repair helps to define the efficacy of treatment in improving sperm parameters of subfertile men. J Endocrinol Invest. 2017 Oct;40(10):1145-1153. doi: 10.1007/s40618-017-0695-x. Epub 2017 May 25. PubMed PMID: 28547739.

 

25: Barbonetti A, Cavallo F, D'Andrea S, Muselli M, Felzani G, Francavilla S, Francavilla F. Lower Vitamin D Levels Are Associated With Depression in People With Chronic Spinal Cord Injury. Arch Phys Med Rehabil. 2017 May;98(5):940-946. doi: 10.1016/j.apmr.2016.11.006. Epub 2016 Dec 14. PubMed PMID: 27986521.

 

26: Barbonetti A, Bisogno T, Battista N, Piscitelli F, Micillo A, Francavilla S, Maccarrone M, Francavilla F. 2-arachidonoylglycerol levels are increased in leukocytospermia and correlate with seminal macrophages. Andrology. 2017 Jan;5(1):87-94. doi: 10.1111/andr.12283. Epub 2016 Nov 11. PubMed PMID: 27863106.

 

27: Barbonetti A, Castellini C, Di Giammarco N, Santilli G, Francavilla S, Francavilla F. In vitro exposure of human spermatozoa to bisphenol A induces pro-oxidative/apoptotic mitochondrial dysfunction. Reprod Toxicol. 2016 Dec;66:61-67. doi: 10.1016/j.reprotox.2016.09.014. Epub 2016 Sep 26. PubMed PMID: 27686954.

 

28: D'Andrea S, Micillo A, Francavilla F, Di Emidio G, Tatone C, Francavilla S, Barbonetti A. Serum From Patients With Erectile Dysfunction and Vascular Risk Factors Triggered an Oxidative Stress-Dependent Mitochondrial Apoptotic Pathway in Ex Vivo Expanded Circulating Angiogenic Cells of Healthy Men. J Sex Med. 2016 Jul;13(7):1063-70. doi: 10.1016/j.jsxm.2016.04.067. Epub 2016 May 13. PubMed PMID: 27184187.

 

29: Micillo A, Vassallo MR, Cordeschi G, D'Andrea S, Necozione S, Francavilla F, Francavilla S, Barbonetti A. Semen leukocytes and oxidative-dependent DNA damage of spermatozoa in male partners of subfertile couples with no symptoms of genital tract infection. Andrology. 2016 Sep;4(5):808-15. doi: 10.1111/andr.12188. Epub 2016 May 6. PubMed PMID: 27153514.

 

30: Barbonetti A, Sperandio A, Micillo A, D'Andrea S, Pacca F, Felzani G, Francavilla S, Francavilla F. Independent Association of Vitamin D With Physical Function in People With Chronic Spinal Cord Injury. Arch Phys Med Rehabil. 2016 May;97(5):726-32. doi: 10.1016/j.apmr.2016.01.002. Epub 2016 Jan 22. PubMed PMID: 26805770.

 

31: Barbonetti A, Vassallo MR, Felzani G, Francavilla S, Francavilla F. Association between 25(OH)-vitamin D and testosterone levels: Evidence from men with chronic spinal cord injury. J Spinal Cord Med. 2016 May;39(3):246-52. doi: 10.1179/2045772315Y.0000000050. Epub 2015 Aug 27. PubMed PMID: 26312544; PubMed Central PMCID: PMC5073757.

 

32: D'Andrea S, Giordano AV, Carducci S, Sacchetti L, Necozione S, Costanzo M, De Gregorio A, Micillo A, Francavilla F, Francavilla S, Barbonetti A. Embolization of left spermatic vein in non-obstructive azoospermic men with varicocele: role of FSH to predict the appearance of ejaculated spermatozoa after treatment. J Endocrinol Invest. 2015 Jul;38(7):785-90. doi: 10.1007/s40618-015-0259-x. Epub 2015 Mar 5. PubMed PMID: 25740066.

 

33: Mastromarino P, Hemalatha R, Barbonetti A, Cinque B, Cifone MG, Tammaro F, Francavilla F. Biological control of vaginosis to improve reproductive health. Indian J Med Res. 2014 Nov;140 Suppl:S91-7. Review. PubMed PMID: 25673551; PubMed Central PMCID: PMC4345761.

 

34: Francavilla F, Barbonetti A. Letter to the editor: comment on Gaspar AP, Brandão CM, Lazaretti-Castro M. Bone mass and hormone analysis in spinal cord injury patients: evidences for a gonadal axis disruption. J Clin Endocrinol Metab. 2015 Feb;100(2):L20. doi: 10.1210/jc.2014-4164. PubMed PMID: 25658158.

 

35: Barbonetti A, Caterina Vassallo MR, Cotugno M, Felzani G, Francavilla S, Francavilla F. Low testosterone and non-alcoholic fatty liver disease: Evidence for their independent association in men with chronic spinal cord injury. J Spinal Cord Med. 2016 Jul;39(4):443-9. doi: 10.1179/2045772314Y.0000000288. Epub 2016 Feb 25. PubMed PMID: 25614040; PubMed Central PMCID: PMC5102293.

 

36: Barbonetti A, Vassallo MR, Pacca F, Cavallo F, Costanzo M, Felzani G, Francavilla S, Francavilla F. Correlates of low testosterone in men with chronic spinal cord injury. Andrology. 2014 Sep;2(5):721-8. doi: 10.1111/j.2047-2927.2014.00235.x. Epub 2014 Jun 13. PubMed PMID: 24925765.

 

37: Pezzella A, Barbonetti A, D'Andrea S, Necozione S, Micillo A, Di Gregorio A, Francavilla F, Francavilla S. Ultrasonographic caput epididymis diameter is reduced in non-obstructive azoospermia compared with normozoospermia but is not predictive for successful sperm retrieval after TESE. Hum Reprod. 2014 Jul;29(7):1368-74. Epub 2014 May 7. PubMed PMID: 24812316.

 

38: Barbonetti A, Vassallo MR, Costanzo M, Battista N, Maccarrone M, Francavilla S, Francavilla F. Involvement of cannabinoid receptor-1 activation in mitochondrial depolarizing effect of lipopolysaccharide in human spermatozoa. Andrology. 2014 Jul;2(4):502-9. doi: 10.1111/j.2047-2927.2014.00210.x. Epub 2014 Apr 1. PubMed PMID: 24692267.

 

39: Pelliccione F, D'Angeli A, D'Andrea S, Barbonetti A, Pezzella A, Necozione S, Falone S, Amicarelli F, Francavilla F, Francavilla S. Tadalafil treatment had a modest effect on endothelial cell damage and repair ability markers in men with erectile dysfunction and vascular risk. Asian J Androl. 2014 Mar-Apr;16(2):290-4. doi: 10.4103/1008-682X.122347. PubMed PMID: 24407182; PubMed Central PMCID: PMC3955343.

 

40: Barbonetti A, Vassallo MR, Cinque B, Filipponi S, Mastromarino P, Cifone MG, Francavilla S, Francavilla F. Soluble products of Escherichia coli induce mitochondrial dysfunction-related sperm membrane lipid peroxidation which is prevented by lactobacilli. PLoS One. 2013 Dec 16;8(12):e83136. doi: 10.1371/journal.pone.0083136. eCollection 2013. PubMed PMID: 24358256; PubMed Central PMCID: PMC3865092.

 

41: Barbonetti A, Vassallo MR, Di Rosa A, Leombruni Y, Felzani G, Gandini L, Lenzi A, Necozione S, Francavilla S, Francavilla F. Involvement of mitochondrial dysfunction in the adverse effect exerted by seminal plasma from men with spinal cord injury on sperm motility. Andrology. 2013 May;1(3):456-63. doi: 10.1111/j.2047-2927.2013.00077.x. Epub 2013 Mar 15. PubMed PMID: 23494980.

 

42: Pezzella A, Barbonetti A, Micillo A, D'Andrea S, Necozione S, Gandini L, Lenzi A, Francavilla F, Francavilla S. Ultrasonographic determination of caput epididymis diameter is strongly predictive of obstruction in the genital tract in azoospermic men with normal serum FSH. Andrology. 2013 Jan;1(1):133-8. doi: 10.1111/j.2047-2927.2012.00010.x. Epub 2012 Oct 9. PubMed PMID: 23258642.

 

43: Pelliccione F, D'Angeli A, Filipponi S, Falone S, Necozione S, Barbonetti A, Francavilla F, Francavilla S. Serum from patients with erectile dysfunction inhibits circulating angiogenic cells from healthy men: relationship with cardiovascular risk, endothelial damage and circulating angiogenic modulators. Int J Androl. 2012 Oct;35(5):645-52. doi: 10.1111/j.1365-2605.2012.01253.x. Epub 2012 Mar 6. PubMed PMID: 22394130.

 

44: Barbonetti A, Cavallo F, Felzani G, Francavilla S, Francavilla F. Erectile dysfunction is the main determinant of psychological distress in men with spinal cord injury. J Sex Med. 2012 Mar;9(3):830-6. doi: 10.1111/j.1743-6109.2011.02599.x. Epub 2011 Dec 21. PubMed PMID: 22188659.

 

45: Barbonetti A, Cinque B, Vassallo MR, Mineo S, Francavilla S, Cifone MG, Francavilla F. Effect of vaginal probiotic lactobacilli on in vitro-induced sperm lipid peroxidation and its impact on sperm motility and viability. Fertil Steril. 2011 Jun 30;95(8):2485-8. doi: 10.1016/j.fertnstert.2011.03.066. Epub 2011 Apr 17. PubMed PMID: 21497805.

 

46: Barbonetti A, Vassallo MR, Fortunato D, Francavilla S, Maccarrone M, Francavilla F. Energetic metabolism and human sperm motility: impact of CB₁ receptor activation. Endocrinology. 2010 Dec;151(12):5882-92. doi: 10.1210/en.2010-0484. Epub 2010 Oct 20. PubMed PMID: 20962050; PubMed Central PMCID: PMC2999496.

 

47: Barbonetti A, Vassallo MR, Cordeschi G, Venetis D, Carboni A, Sperandio A, Felzani G, Francavilla S, Francavilla F. Protein tyrosine phosphorylation of the human sperm head during capacitation: immunolocalization and relationship with acquisition of sperm-fertilizing ability. Asian J Androl. 2010 Nov;12(6):853-61. doi: 10.1038/aja.2010.52. Epub 2010 Aug 9. PubMed PMID: 20694019; PubMed Central PMCID: PMC3739072.

 

48: Barbonetti A, Vassallo MR, Pelliccione F, D'Angeli A, Santucci R, Muciaccia B, Stefanini M, Francavilla F, Francavilla S. Beta-chemokine receptor CCR5 in human spermatozoa and its relationship with seminal parameters. Hum Reprod. 2009 Dec;24(12):2979-87. doi: 10.1093/humrep/dep304. Epub 2009 Sep 3. PubMed PMID: 19729379.

 

49: Francavilla F, Battista N, Barbonetti A, Vassallo MR, Rapino C, Antonangelo C, Pasquariello N, Catanzaro G, Barboni B, Maccarrone M. Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability. Endocrinology. 2009 Oct;150(10):4692-700. doi: 10.1210/en.2009-0057. Epub 2009 Jul 16. PubMed PMID: 19608651.

 

50: Francavilla F, Sciarretta F, Sorgentone S, Necozione S, Santucci R, Barbonetti A, Francavilla S. Intrauterine insemination with or without mild ovarian stimulation in couples with male subfertility due to oligo/astheno- and/or teratozoospermia or antisperm antibodies: a prospective cross-over trial. Fertil Steril. 2009 Sep;92(3):1009-11. doi: 10.1016/j.fertnstert.2009.01.112. Epub 2009 Mar 3. PubMed PMID: 19261275.

 

51: Barbonetti A, Vassallo MR, Cinque B, Antonangelo C, Sciarretta F, Santucci R, D'Angeli A, Francavilla S, Francavilla F. Dynamics of the global tyrosine phosphorylation during capacitation and acquisition of the ability to fuse with oocytes in human spermatozoa. Biol Reprod. 2008 Oct;79(4):649-56. doi: 10.1095/biolreprod.108.068254. Epub 2008 Jun 18. PubMed PMID: 18562705.

 

52: Pandolfi C, Zugaro A, Lattanzio F, Necozione S, Barbonetti A, Colangeli MS, Francavilla S, Francavilla F. Low birth weight and later development of insulin resistance and biochemical/clinical features of polycystic ovary syndrome. Metabolism. 2008 Jul;57(7):999-1004. doi: 10.1016/j.metabol.2008.02.018. PubMed PMID: 18555843.

 

53: Barbonetti A, Vassallo MR, Antonangelo C, Nuccetelli V, D'Angeli A, Pelliccione F, Giorgi M, Francavilla F, Francavilla S. RANTES and human sperm fertilizing ability: effect on acrosome reaction and sperm/oocyte fusion. Mol Hum Reprod. 2008 Jul;14(7):387-91. doi: 10.1093/molehr/gan031. Epub 2008 May 18. PubMed PMID: 18490356.

 

54: Zugaro A, Pandolfi C, Barbonetti A, Vassallo MR, D'Angeli A, Necozione S, Colangeli MS, Francavilla S, Francavilla F. Retinol binding protein 4, low birth weight-related insulin resistance and hormonal contraception. Endocrine. 2007 Oct;32(2):166-9. Epub 2007 Dec 5. PubMed PMID: 18058259.

 

55: Francavilla F, Santucci R, Barbonetti A, Francavilla S. Naturally-occurring antisperm antibodies in men: interference with fertility and clinical implications. An update. Front Biosci. 2007 May 1;12:2890-911. Review. PubMed PMID: 17485267.

 

56: Francavilla F, Barbonetti A, Necozione S, Santucci R, Cordeschi G, Macerola B, Francavilla S. Within-subject variation of seminal parameters in men with infertile marriages. Int J Androl. 2007 Jun;30(3):174-81. Epub 2007 Jan 19. PubMed PMID: 17239086.

 

57: Barbonetti A, Zugaro A, Sciarretta F, Santucci R, Necozione S, Ruvolo G, Francavilla S, Francavilla F. The inhibition of the human sperm phosphatidylinosytol 3-kinase by LY294002 does not interfere with sperm/oocyte interaction. Int J Androl. 2006 Aug;29(4):468-74. Epub 2006 Feb 15. PubMed PMID: 16480410.


Altre pubblicazioni (inclusi contributi in capitoli di libri):

 

1. Santucci R, Barbonetti A, Necozione S, Francavilla F. Valutazione dei trattamenti dell’ipofertilità idiopatica maschile: quale end-point? Foresta C. (ed). La riproduzione umana e le influenze ambientali, Libraria Editrice Università di Padova, 2006: pp. 61-68.


2. Barbonetti A, Sciarretta F, Francavilla F. Fisiopatologia iatrogena. Lenzi A., Jannini E.A., Maggi M. (eds). Trattato di sessuologia medica, Elsevier Masson, 2007; Cap. 59 (impotenza): pp. 291-298.

 

3. Francavilla F, Barbonetti A. Male Autoimmune Infertility. In: WKH Krause and RK Naz (eds.), Immune Infertility, ©Springer Verlag Berlin Heidelberg, 2009: pp. 145-153.

 

4. Francavilla F, Barbonetti A. Infertilità. Attanasio R., Castello R., Dorizzi R., Ferone D., Giagulli V., Lenzi A., Martinelli M., Toscano V., Valentini F., Valota M. (eds.), Diagnostica in Endocrinologia Clinica – Manuale per valutazione e inquadramento delle patologie gonadiche, Scripta s.c. press., Verona, 2009: pp. 143-155; 311-313.

 

5. Barbonetti A, Cordeschi G, Francavilla F. Indicazione e metodi di crioconservazione degli spermatozoi. Foresta C., Ferlin A., Lenzi A., Garolla A. (eds), La medicina della riproduzione dalla sperimentazione alla clinica, CLEUPS S.c. Libraria Editrice Università di Padova, 2011: pp. 315-319.

 

6. Barbonetti A, Francavilla F. Biochimica del liquido seminale. Lenzi A., Foresta C., Jannini E.A., Maggi M. (eds), Guida allo studio dell’andrologia, Società Editrice Universo, 2012; Cap. 9: pp. 65-70.

 

7. Francavilla F, Barbonetti A. Infertility: Immunological Aspects. 2012; In: eLS. John Wiley & Sons, Ltd: Chichester. DOI: 10.1002/978047001 5902.a0000967. pub2. www.els.net.

 

8. Francavilla F, Barbonetti A. Male Autoimmune Infertility. In: WKH Krause & RK Naz (eds.): Immune infertility: Impact of Immune Reactions on Human Fertility. Second Edition. ©Springer Verlag Berlin Heidelberg, 2017: pp. 187-196.

 

9. Barbonetti A, Sciarretta F, Francavilla F. Fisiopatologia iatrogena. EA Jannini, A Lenzi, M Maggi (eds). Sessuologia medica. Trattato di psicosessuologia, medicina della sessualità e salute della coppia, Seconda edizione. Edra S.p.A., Milano, 2017; Cap. 61 (Patologia dell’erezione): pp. 308-316.

 

10. Ciocca G, Zauri S, Limoncin E, Mollaioli D, Niolu C, Bianciardi E, Siracusano A, D'Andrea S, Barbonetti A, Jannini EA. Psicoendocrinologia e psicopatologia delle transizioni di genere. Noos 2018;24(3):135-141. DOI: 10.1722/3152.31323.

 

11. Francavilla F, Barbonetti A, D’Andrea S, Francavilla S. Diagnostica e approccio terapeutico della induratio penis plastica. L'Endocrinologo 2019;20:33. https://doi.org/10.1007/s40619-019-00518-z.

Prodotti della ricerca

 

1: Barbonetti A, Castellini C, D'Andrea S, Minaldi E, Totaro M, Francavilla S, Francavilla F. Relationship between natural and intrauterine insemination-assisted live births and the degree of sperm autoimmunisation. Hum Reprod. 2020 May 2. pii: deaa070. doi: 10.1093/humrep/deaa070. [Epub ahead of print] PubMed PMID: 32358600.

 

2: Lotti F, Frizza F, Balercia G, Barbonetti A, Behre HM, Calogero AE, Cremers JF, Francavilla F, Isidori AM, Kliesch S, La Vignera S, Lenzi A, Marcou M, Pilatz A, Poolamets O, Punab M, Peraza Godoy MF, Rajmil O, Salvio G, Shaeer O, Weidner W, Maseroli E, Cipriani S, Baldi E, Degl'Innocenti S, Danza G, Caldini AL, Terreni A, Boni L, Krausz C, Maggi M. The European Academy of Andrology (EAA) ultrasound study on healthy, fertile men: clinical, seminal and biochemical characteristics. Andrology. 2020 Apr 30. doi: 10.1111/andr.12808. [Epub ahead of print] PubMed PMID: 32353207.

 

3: D'Andrea S, Spaggiari G, Barbonetti A, Santi D. Endogenous transient doping: physical exercise acutely increases testosterone levels-results from a meta-analysis. J Endocrinol Invest. 2020 Apr 15. doi: 10.1007/s40618-020-01251-3. [Epub ahead of print] Review. PubMed PMID: 32297287.

 

4: D'Andrea S, Castellini C, Minaldi E, Totaro M, Felzani G, Francavilla S, Francavilla F, Barbonetti A. Testosterone, level of the lesion and age are independently associated with prostate volume in men with chronic spinal cord injury. J Endocrinol Invest. 2020 Apr 4. doi: 10.1007/s40618-020-01243-3. [Epub ahead of print] PubMed PMID: 32248510.

 

5: D'Andrea S, Minaldi E, Castellini C, Cavallo F, Felzani G, Francavilla S, Francavilla F, Barbonetti A. Independent Association of Erectile Dysfunction and Low Testosterone Levels With Life Dissatisfaction in Men With Chronic Spinal Cord Injury. J Sex Med. 2020 May;17(5):911-918. doi: 10.1016/j.jsxm.2020.01.018. Epub 2020 Feb 20. PubMed PMID: 32089485.

 

6: Barbonetti A, D'Andrea S, Francavilla S. Testosterone replacement therapy. Andrology. 2020 Feb 18. doi: 10.1111/andr.12774. [Epub ahead of print] Review. PubMed PMID: 32068334.

 

7: D'Andrea S, Castellini C, Paladino V, Totaro M, Felzani G, Francavilla S, Francavilla F, Barbonetti A. Metabolic syndrome is the key determinant of impaired vaginal lubrication in women with chronic spinal cord injury. J Endocrinol Invest. 2020 Jan 25. doi: 10.1007/s40618-020-01185-w. [Epub ahead of print] PubMed PMID: 31983040.

 

8: D'Andrea S, Pallotti F, Senofonte G, Castellini C, Paoli D, Lombardo F, Lenzi A, Francavilla S, Francavilla F, Barbonetti A. Polymorphic Cytosine-Adenine-Guanine Repeat Length of Androgen Receptor Gene and Gender Incongruence in Trans Women: A Systematic Review and Meta-Analysis of Case-Control Studies. J Sex Med. 2020 Mar;17(3):543-550. doi: 10.1016/j.jsxm.2019.12.010. Epub 2020 Jan 8. PubMed PMID: 31926901.

 

9: Minaldi E, D'Andrea S, Castellini C, Martorella A, Francavilla F, Francavilla S, Barbonetti A. Thyroid autoimmunity and risk of post-partum depression: a systematic review and meta-analysis of longitudinal studies. J Endocrinol Invest. 2020 Mar;43(3):271-277. doi: 10.1007/s40618-019-01120-8. Epub 2019 Sep 24. Review. PubMed PMID: 31552596.

 

10: Castellini C, D'Andrea S, Martorella A, Minaldi E, Necozione S, Francavilla F, Francavilla S, Barbonetti A. Relationship between leukocytospermia, reproductive potential after assisted reproductive technology, and sperm parameters: a systematic review and meta-analysis of case-control studies. Andrology. 2020 Jan;8(1):125-135. doi: 10.1111/andr.12662. Epub 2019 Jun 28. PubMed PMID: 31250986.

 

11: D'Andrea S, Barbonetti A, Castellini C, Nolletti L, Martorella A, Minaldi E, Giordano AV, Carducci S, Necozione S, Francavilla F, Francavilla S. Left spermatic vein reflux after varicocele repair predicts pregnancies and live births in subfertile couples. J Endocrinol Invest. 2019 Oct;42(10):1215-1221. doi: 10.1007/s40618-019-01042-5. Epub 2019 Apr 6. PubMed PMID: 30955179.

 

12: Barbonetti A, Martorella A, Minaldi E, D'Andrea S, Bardhi D, Castellini C, Francavilla F, Francavilla S. Testicular Cancer in Infertile Men With and Without Testicular Microlithiasis: A Systematic Review and Meta-Analysis of Case-Control Studies. Front Endocrinol (Lausanne). 2019 Mar 21;10:164. doi: 10.3389/fendo.2019.00164. eCollection 2019. PubMed PMID: 30949131; PubMed Central PMCID: PMC6437042.

 

13: Barbonetti A, Castellini C, D'Andrea S, Cordeschi G, Santucci R, Francavilla S, Francavilla F. Prevalence of anti-sperm antibodies and relationship of degree of sperm auto-immunization to semen parameters and post-coital test outcome: a retrospective analysis of over 10 000 men. Hum Reprod. 2019 May 1;34(5):834-841. doi: 10.1093/humrep/dez030. PubMed PMID: 30927424.

 

14: Barbonetti A, D'Andrea S, Cavallo F, Martorella A, Francavilla S, Francavilla F. Erectile Dysfunction and Premature Ejaculation in Homosexual and Heterosexual Men: A Systematic Review and Meta-Analysis of Comparative Studies. J Sex Med. 2019 May;16(5):624-632. doi: 10.1016/j.jsxm.2019.02.014. Epub 2019 Mar 26. Review. PubMed PMID: 30926517.

 

15: Guadagni V, Sarà M, Conson M, Carolei A, Sacco S, Vadini S, Pistarini C, Barbonetti A, Iaria G, Pistoia F. Cognitive and Emotional Empathy in Individuals with Spinal Cord Injury. Behav Neurol. 2019 Feb 10;2019:1312934. doi: 10.1155/2019/1312934. eCollection 2019. PubMed PMID: 30881519; PubMed Central PMCID: PMC6387693.

 

16: D'Andrea S, Barbonetti A, Martorella A, Necozione S, Francavilla F, Francavilla S. Effect of prolonged treatment with phosphodiesterase-5-inhibitors on endothelial dysfunction in vascular diseases and vascular risk conditions: A systematic review analysis and meta-analysis of randomized double-blind placebo-controlled trials. Int J Clin Pract. 2019 Feb;73(2):e13296. doi: 10.1111/ijcp.13296. Epub 2018 Dec 18. PubMed PMID: 30471172.

 

17: D'Andrea S, Barbonetti A, Castellini C, Martorella A, Minaldi E, Viktor Giordano A, Carducci S, Necozione S, Francavilla F, Francavilla S. Reproductive hormones and sperm parameters after varicocele repair: An observational study. Andrologia. 2018 Dec;50(10):e13118. doi: 10.1111/and.13118. Epub 2018 Jul 25. PubMed PMID: 30043529.

 

18: Barbonetti A, D'Andrea S, Martorella A, Felzani G, Francavilla S, Francavilla F. Risk of prostate cancer in men with spinal cord injury: A systematic review and meta-analysis. Asian J Androl. 2018 Nov-Dec;20(6):555-560. doi: 10.4103/aja.aja_31_18. PubMed PMID: 29956686; PubMed Central PMCID: PMC6219305.

 

19: Vezzani S, Giannetta E, Altieri B, Barbonetti A, Bellastella G, Certo R, Cignarelli A, Cinti F, D'Andrea S, Di Dalmazi G, Frara S, Garelli S, Giuffrida G, Maiorino MI, Mele C, Mezza T, Pani MG, Samà MT, Satta C, Santi D. AN ITALIAN SURVEY OF COMPLIANCE WITH MAJOR GUIDELINES FOR L-THYROXINE OF PRIMARY HYPOTHYROIDISM. Endocr Pract. 2018 May;24(5):419-428. doi: 10.4158/EP-2017-0159. PubMed PMID: 29847168.

 

20: Barbonetti A, D'Andrea S, Samavat J, Martorella A, Felzani G, Francavilla S, Luconi M, Francavilla F. Can the positive association of osteocalcin with testosterone be unmasked when the preeminent hypothalamic-pituitary regulation of testosterone production is impaired? The model of spinal cord injury. J Endocrinol Invest. 2019 Feb;42(2):167-173. doi: 10.1007/s40618-018-0897-x. Epub 2018 May 4. PubMed PMID: 29729005.

 

21: Tatone C, Di Emidio G, Barbonetti A, Carta G, Luciano AM, Falone S, Amicarelli F. Sirtuins in gamete biology and reproductive physiology: emerging roles and therapeutic potential in female and male infertility. Hum Reprod Update. 2018 May 1;24(3):267-289. doi: 10.1093/humupd/dmy003. Review. PubMed PMID: 29447380.

 

22: Barbonetti A, Calogero AE, Balercia G, Garolla A, Krausz C, La Vignera S, Lombardo F, Jannini EA, Maggi M, Lenzi A, Foresta C, Ferlin A. The use of follicle stimulating hormone (FSH) for the treatment of the infertile man: position statement from the Italian Society of Andrology and Sexual Medicine (SIAMS). J Endocrinol Invest. 2018 Sep;41(9):1107-1122. doi: 10.1007/s40618-018-0843-y. Epub 2018 Feb 1. PubMed PMID: 29392544.

 

23: Barbonetti A, D'Andrea S, Martorella A, Felzani G, Francavilla S, Francavilla F. Low vitamin D levels are independent predictors of 1-year worsening in physical function in people with chronic spinal cord injury: a longitudinal study. Spinal Cord. 2018 May;56(5):494-501. doi: 10.1038/s41393-017-0058-7. Epub 2018 Jan 16. PubMed PMID: 29335474.

 

24: D'Andrea S, Micillo A, Barbonetti A, Giordano AV, Carducci S, Mancini A, Necozione S, Francavilla F, Francavilla S. Determination of spermatic vein reflux after varicocele repair helps to define the efficacy of treatment in improving sperm parameters of subfertile men. J Endocrinol Invest. 2017 Oct;40(10):1145-1153. doi: 10.1007/s40618-017-0695-x. Epub 2017 May 25. PubMed PMID: 28547739.

 

25: Barbonetti A, Cavallo F, D'Andrea S, Muselli M, Felzani G, Francavilla S, Francavilla F. Lower Vitamin D Levels Are Associated With Depression in People With Chronic Spinal Cord Injury. Arch Phys Med Rehabil. 2017 May;98(5):940-946. doi: 10.1016/j.apmr.2016.11.006. Epub 2016 Dec 14. PubMed PMID: 27986521.

 

26: Barbonetti A, Bisogno T, Battista N, Piscitelli F, Micillo A, Francavilla S, Maccarrone M, Francavilla F. 2-arachidonoylglycerol levels are increased in leukocytospermia and correlate with seminal macrophages. Andrology. 2017 Jan;5(1):87-94. doi: 10.1111/andr.12283. Epub 2016 Nov 11. PubMed PMID: 27863106.

 

27: Barbonetti A, Castellini C, Di Giammarco N, Santilli G, Francavilla S, Francavilla F. In vitro exposure of human spermatozoa to bisphenol A induces pro-oxidative/apoptotic mitochondrial dysfunction. Reprod Toxicol. 2016 Dec;66:61-67. doi: 10.1016/j.reprotox.2016.09.014. Epub 2016 Sep 26. PubMed PMID: 27686954.

 

28: D'Andrea S, Micillo A, Francavilla F, Di Emidio G, Tatone C, Francavilla S, Barbonetti A. Serum From Patients With Erectile Dysfunction and Vascular Risk Factors Triggered an Oxidative Stress-Dependent Mitochondrial Apoptotic Pathway in Ex Vivo Expanded Circulating Angiogenic Cells of Healthy Men. J Sex Med. 2016 Jul;13(7):1063-70. doi: 10.1016/j.jsxm.2016.04.067. Epub 2016 May 13. PubMed PMID: 27184187.

 

29: Micillo A, Vassallo MR, Cordeschi G, D'Andrea S, Necozione S, Francavilla F, Francavilla S, Barbonetti A. Semen leukocytes and oxidative-dependent DNA damage of spermatozoa in male partners of subfertile couples with no symptoms of genital tract infection. Andrology. 2016 Sep;4(5):808-15. doi: 10.1111/andr.12188. Epub 2016 May 6. PubMed PMID: 27153514.

 

30: Barbonetti A, Sperandio A, Micillo A, D'Andrea S, Pacca F, Felzani G, Francavilla S, Francavilla F. Independent Association of Vitamin D With Physical Function in People With Chronic Spinal Cord Injury. Arch Phys Med Rehabil. 2016 May;97(5):726-32. doi: 10.1016/j.apmr.2016.01.002. Epub 2016 Jan 22. PubMed PMID: 26805770.

 

31: Barbonetti A, Vassallo MR, Felzani G, Francavilla S, Francavilla F. Association between 25(OH)-vitamin D and testosterone levels: Evidence from men with chronic spinal cord injury. J Spinal Cord Med. 2016 May;39(3):246-52. doi: 10.1179/2045772315Y.0000000050. Epub 2015 Aug 27. PubMed PMID: 26312544; PubMed Central PMCID: PMC5073757.

 

32: D'Andrea S, Giordano AV, Carducci S, Sacchetti L, Necozione S, Costanzo M, De Gregorio A, Micillo A, Francavilla F, Francavilla S, Barbonetti A. Embolization of left spermatic vein in non-obstructive azoospermic men with varicocele: role of FSH to predict the appearance of ejaculated spermatozoa after treatment. J Endocrinol Invest. 2015 Jul;38(7):785-90. doi: 10.1007/s40618-015-0259-x. Epub 2015 Mar 5. PubMed PMID: 25740066.

 

33: Mastromarino P, Hemalatha R, Barbonetti A, Cinque B, Cifone MG, Tammaro F, Francavilla F. Biological control of vaginosis to improve reproductive health. Indian J Med Res. 2014 Nov;140 Suppl:S91-7. Review. PubMed PMID: 25673551; PubMed Central PMCID: PMC4345761.

 

34: Francavilla F, Barbonetti A. Letter to the editor: comment on Gaspar AP, Brandão CM, Lazaretti-Castro M. Bone mass and hormone analysis in spinal cord injury patients: evidences for a gonadal axis disruption. J Clin Endocrinol Metab. 2015 Feb;100(2):L20. doi: 10.1210/jc.2014-4164. PubMed PMID: 25658158.

 

35: Barbonetti A, Caterina Vassallo MR, Cotugno M, Felzani G, Francavilla S, Francavilla F. Low testosterone and non-alcoholic fatty liver disease: Evidence for their independent association in men with chronic spinal cord injury. J Spinal Cord Med. 2016 Jul;39(4):443-9. doi: 10.1179/2045772314Y.0000000288. Epub 2016 Feb 25. PubMed PMID: 25614040; PubMed Central PMCID: PMC5102293.

 

36: Barbonetti A, Vassallo MR, Pacca F, Cavallo F, Costanzo M, Felzani G, Francavilla S, Francavilla F. Correlates of low testosterone in men with chronic spinal cord injury. Andrology. 2014 Sep;2(5):721-8. doi: 10.1111/j.2047-2927.2014.00235.x. Epub 2014 Jun 13. PubMed PMID: 24925765.

 

37: Pezzella A, Barbonetti A, D'Andrea S, Necozione S, Micillo A, Di Gregorio A, Francavilla F, Francavilla S. Ultrasonographic caput epididymis diameter is reduced in non-obstructive azoospermia compared with normozoospermia but is not predictive for successful sperm retrieval after TESE. Hum Reprod. 2014 Jul;29(7):1368-74. Epub 2014 May 7. PubMed PMID: 24812316.

 

38: Barbonetti A, Vassallo MR, Costanzo M, Battista N, Maccarrone M, Francavilla S, Francavilla F. Involvement of cannabinoid receptor-1 activation in mitochondrial depolarizing effect of lipopolysaccharide in human spermatozoa. Andrology. 2014 Jul;2(4):502-9. doi: 10.1111/j.2047-2927.2014.00210.x. Epub 2014 Apr 1. PubMed PMID: 24692267.

 

39: Pelliccione F, D'Angeli A, D'Andrea S, Barbonetti A, Pezzella A, Necozione S, Falone S, Amicarelli F, Francavilla F, Francavilla S. Tadalafil treatment had a modest effect on endothelial cell damage and repair ability markers in men with erectile dysfunction and vascular risk. Asian J Androl. 2014 Mar-Apr;16(2):290-4. doi: 10.4103/1008-682X.122347. PubMed PMID: 24407182; PubMed Central PMCID: PMC3955343.

 

40: Barbonetti A, Vassallo MR, Cinque B, Filipponi S, Mastromarino P, Cifone MG, Francavilla S, Francavilla F. Soluble products of Escherichia coli induce mitochondrial dysfunction-related sperm membrane lipid peroxidation which is prevented by lactobacilli. PLoS One. 2013 Dec 16;8(12):e83136. doi: 10.1371/journal.pone.0083136. eCollection 2013. PubMed PMID: 24358256; PubMed Central PMCID: PMC3865092.

 

41: Barbonetti A, Vassallo MR, Di Rosa A, Leombruni Y, Felzani G, Gandini L, Lenzi A, Necozione S, Francavilla S, Francavilla F. Involvement of mitochondrial dysfunction in the adverse effect exerted by seminal plasma from men with spinal cord injury on sperm motility. Andrology. 2013 May;1(3):456-63. doi: 10.1111/j.2047-2927.2013.00077.x. Epub 2013 Mar 15. PubMed PMID: 23494980.

 

42: Pezzella A, Barbonetti A, Micillo A, D'Andrea S, Necozione S, Gandini L, Lenzi A, Francavilla F, Francavilla S. Ultrasonographic determination of caput epididymis diameter is strongly predictive of obstruction in the genital tract in azoospermic men with normal serum FSH. Andrology. 2013 Jan;1(1):133-8. doi: 10.1111/j.2047-2927.2012.00010.x. Epub 2012 Oct 9. PubMed PMID: 23258642.

 

43: Pelliccione F, D'Angeli A, Filipponi S, Falone S, Necozione S, Barbonetti A, Francavilla F, Francavilla S. Serum from patients with erectile dysfunction inhibits circulating angiogenic cells from healthy men: relationship with cardiovascular risk, endothelial damage and circulating angiogenic modulators. Int J Androl. 2012 Oct;35(5):645-52. doi: 10.1111/j.1365-2605.2012.01253.x. Epub 2012 Mar 6. PubMed PMID: 22394130.

 

44: Barbonetti A, Cavallo F, Felzani G, Francavilla S, Francavilla F. Erectile dysfunction is the main determinant of psychological distress in men with spinal cord injury. J Sex Med. 2012 Mar;9(3):830-6. doi: 10.1111/j.1743-6109.2011.02599.x. Epub 2011 Dec 21. PubMed PMID: 22188659.

 

45: Barbonetti A, Cinque B, Vassallo MR, Mineo S, Francavilla S, Cifone MG, Francavilla F. Effect of vaginal probiotic lactobacilli on in vitro-induced sperm lipid peroxidation and its impact on sperm motility and viability. Fertil Steril. 2011 Jun 30;95(8):2485-8. doi: 10.1016/j.fertnstert.2011.03.066. Epub 2011 Apr 17. PubMed PMID: 21497805.

 

46: Barbonetti A, Vassallo MR, Fortunato D, Francavilla S, Maccarrone M, Francavilla F. Energetic metabolism and human sperm motility: impact of CB₁ receptor activation. Endocrinology. 2010 Dec;151(12):5882-92. doi: 10.1210/en.2010-0484. Epub 2010 Oct 20. PubMed PMID: 20962050; PubMed Central PMCID: PMC2999496.

 

47: Barbonetti A, Vassallo MR, Cordeschi G, Venetis D, Carboni A, Sperandio A, Felzani G, Francavilla S, Francavilla F. Protein tyrosine phosphorylation of the human sperm head during capacitation: immunolocalization and relationship with acquisition of sperm-fertilizing ability. Asian J Androl. 2010 Nov;12(6):853-61. doi: 10.1038/aja.2010.52. Epub 2010 Aug 9. PubMed PMID: 20694019; PubMed Central PMCID: PMC3739072.

 

48: Barbonetti A, Vassallo MR, Pelliccione F, D'Angeli A, Santucci R, Muciaccia B, Stefanini M, Francavilla F, Francavilla S. Beta-chemokine receptor CCR5 in human spermatozoa and its relationship with seminal parameters. Hum Reprod. 2009 Dec;24(12):2979-87. doi: 10.1093/humrep/dep304. Epub 2009 Sep 3. PubMed PMID: 19729379.

 

49: Francavilla F, Battista N, Barbonetti A, Vassallo MR, Rapino C, Antonangelo C, Pasquariello N, Catanzaro G, Barboni B, Maccarrone M. Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability. Endocrinology. 2009 Oct;150(10):4692-700. doi: 10.1210/en.2009-0057. Epub 2009 Jul 16. PubMed PMID: 19608651.

 

50: Francavilla F, Sciarretta F, Sorgentone S, Necozione S, Santucci R, Barbonetti A, Francavilla S. Intrauterine insemination with or without mild ovarian stimulation in couples with male subfertility due to oligo/astheno- and/or teratozoospermia or antisperm antibodies: a prospective cross-over trial. Fertil Steril. 2009 Sep;92(3):1009-11. doi: 10.1016/j.fertnstert.2009.01.112. Epub 2009 Mar 3. PubMed PMID: 19261275.

 

51: Barbonetti A, Vassallo MR, Cinque B, Antonangelo C, Sciarretta F, Santucci R, D'Angeli A, Francavilla S, Francavilla F. Dynamics of the global tyrosine phosphorylation during capacitation and acquisition of the ability to fuse with oocytes in human spermatozoa. Biol Reprod. 2008 Oct;79(4):649-56. doi: 10.1095/biolreprod.108.068254. Epub 2008 Jun 18. PubMed PMID: 18562705.

 

52: Pandolfi C, Zugaro A, Lattanzio F, Necozione S, Barbonetti A, Colangeli MS, Francavilla S, Francavilla F. Low birth weight and later development of insulin resistance and biochemical/clinical features of polycystic ovary syndrome. Metabolism. 2008 Jul;57(7):999-1004. doi: 10.1016/j.metabol.2008.02.018. PubMed PMID: 18555843.

 

53: Barbonetti A, Vassallo MR, Antonangelo C, Nuccetelli V, D'Angeli A, Pelliccione F, Giorgi M, Francavilla F, Francavilla S. RANTES and human sperm fertilizing ability: effect on acrosome reaction and sperm/oocyte fusion. Mol Hum Reprod. 2008 Jul;14(7):387-91. doi: 10.1093/molehr/gan031. Epub 2008 May 18. PubMed PMID: 18490356.

 

54: Zugaro A, Pandolfi C, Barbonetti A, Vassallo MR, D'Angeli A, Necozione S, Colangeli MS, Francavilla S, Francavilla F. Retinol binding protein 4, low birth weight-related insulin resistance and hormonal contraception. Endocrine. 2007 Oct;32(2):166-9. Epub 2007 Dec 5. PubMed PMID: 18058259.

 

55: Francavilla F, Santucci R, Barbonetti A, Francavilla S. Naturally-occurring antisperm antibodies in men: interference with fertility and clinical implications. An update. Front Biosci. 2007 May 1;12:2890-911. Review. PubMed PMID: 17485267.

 

56: Francavilla F, Barbonetti A, Necozione S, Santucci R, Cordeschi G, Macerola B, Francavilla S. Within-subject variation of seminal parameters in men with infertile marriages. Int J Androl. 2007 Jun;30(3):174-81. Epub 2007 Jan 19. PubMed PMID: 17239086.

 

57: Barbonetti A, Zugaro A, Sciarretta F, Santucci R, Necozione S, Ruvolo G, Francavilla S, Francavilla F. The inhibition of the human sperm phosphatidylinosytol 3-kinase by LY294002 does not interfere with sperm/oocyte interaction. Int J Androl. 2006 Aug;29(4):468-74. Epub 2006 Feb 15. PubMed PMID: 16480410.

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